SCOPe 2.02: Protein: Ubiquitin conjugating enzyme, UBC

Lineage for Protein: Ubiquitin conjugating enzyme, UBC

Root: SCOPe 2.02
Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
Fold d.20: UBC-like [54494] (1 superfamily)
alpha-beta(4)-alpha(3); core: meander beta-sheet plus one helix 2
Superfamily d.20.1: UBC-like [54495] (5 families)
Family d.20.1.1: UBC-related [54496] (7 proteins)
Protein Ubiquitin conjugating enzyme, UBC [54497] (33 species)

Species:

African clawed frog (Xenopus laevis) [TaxId:8355] [160080] (1 PDB entry)
- Domain for 3eb6:
  - Domain d3eb6b1: 3eb6 B:1-147 [158081]
    automatically matched to d1ur6a_
    complexed with zn
Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [187672] (2 PDB entries)
1. Domains for 2eke:
  1. Domain d2ekea_: 2eke A: [161413]
    Other proteins in same PDB: d2ekec1, d2eked1
    automated match to d1a3sa_
  2. Domain d2ekeb_: 2eke B: [161414]
    Other proteins in same PDB: d2ekec1, d2eked1
    automated match to d1a3sa_
2. Domains for 2gjd:
  1. Domain d2gjda_: 2gjd A: [164730]
    automated match to d1a3sa_
  2. Domain d2gjdb_: 2gjd B: [164731]
    automated match to d1a3sa_
  3. Domain d2gjdc_: 2gjd C: [164732]
    automated match to d1a3sa_
  4. Domain d2gjdd_: 2gjd D: [164733]
    automated match to d1a3sa_
Baker's yeast (Saccharomyces cerevisiae), mms2 [TaxId:4932] [64241] (2 PDB entries)
1. Domain for 1jat:
  - Domain d1jatb_: 1jat B: [62819]
    complexed with ubc13
2. Domain for 2gmi:
  - Domain d2gmib_: 2gmi B: [135381]
    Other proteins in same PDB: d2gmic_
    automated match to d1jatb_
Baker's yeast (Saccharomyces cerevisiae), ubc1 [TaxId:4932] [69685] (3 PDB entries)
Uniprot P21734
1. Domain for 1fxt:
  - Domain d1fxta_: 1fxt A: [65055]
    Other proteins in same PDB: d1fxtb_
2. Domains for 1fzy:
  1. Domain d1fzya_: 1fzy A: [65072]
  2. Domain d1fzyb_: 1fzy B: [65073]
3. Domain for 1tte:
  - Domain d1ttea2: 1tte A:2-160 [107296]
    Other proteins in same PDB: d1ttea1
Baker's yeast (Saccharomyces cerevisiae), ubc13 [TaxId:4932] [64239] (4 PDB entries)
1. Domain for 1jat:
  - Domain d1jata_: 1jat A: [62818]
    complexed with Mms2
2. Domains for 1jbb:
  1. Domain d1jbba_: 1jbb A: [62842]
  2. Domain d1jbbb_: 1jbb B: [62843]
3. Domain for 2gmi:
  - Domain d2gmia1: 2gmi A:1-152 [145218]
    Other proteins in same PDB: d2gmic_
4. Domain for 4fh1:
  - Domain d4fh1a_: 4fh1 A: [193058]
    automated match to d2gmia1
    complexed with nhe
Baker's yeast (Saccharomyces cerevisiae), ubc2 (RAD6) [TaxId:4932] [54499] (1 PDB entry)
- Domains for 1ayz:
  1. Domain d1ayza_: 1ayz A: [38326]
  2. Domain d1ayzb_: 1ayz B: [38327]
  3. Domain d1ayzc_: 1ayz C: [38328]
Baker's yeast (Saccharomyces cerevisiae), ubc4 [TaxId:4932] [54500] (1 PDB entry)
- Domain for 1qcq:
  - Domain d1qcqa_: 1qcq A: [38329]
Baker's yeast (Saccharomyces cerevisiae), ubc7 [TaxId:4932] [54501] (1 PDB entry)
- Domain for 2ucz:
  - Domain d2ucza_: 2ucz A: [38330]
Caenorhabditis elegans, E2 2 [TaxId:6239] [143060] (1 PDB entry)
Uniprot P35129 1-147
- Domain for 1z2u:
  - Domain d1z2ua1: 1z2u A:1-147 [124389]
    complexed with bu3, cl, na, unx
Clam (Spisula solidissima), E-2C [TaxId:6584] [54504] (1 PDB entry)
- Domain for 2e2c:
  - Domain d2e2ca_: 2e2c A: [38336]
Human (Homo sapiens), E2 D3 [TaxId:9606] [143054] (3 PDB entries)
Uniprot P61077 1-147
1. Domain for 1x23:
  - Domain d1x23a1: 1x23 A:1-147 [121615]
    Other proteins in same PDB: d1x23b_, d1x23c_, d1x23d_
2. Domain for 2fuh:
  - Domain d2fuha1: 2fuh A:2-147 [134173]
    Other proteins in same PDB: d2fuhb1
    automatically matched to 1X23 A:1-147
3. Domain for 3ugb:
  - Domain d3ugba_: 3ugb A: [195361]
    automated match to d1x23a1
    complexed with gol
Human (Homo sapiens), E2 G1 [TaxId:9606] [143056] (1 PDB entry)
Uniprot P62253 7-131
- Domain for 2awf:
  - Domain d2awfa1: 2awf A:7-131 [127432]
Human (Homo sapiens), E2 H [TaxId:9606] [143055] (1 PDB entry)
Uniprot P62256 4-155
- Domains for 2z5d:
  1. Domain d2z5da1: 2z5d A:23-174 [171058]
    complexed with na
  2. Domain d2z5db1: 2z5d B:25-174 [171059]
    automatically matched to 1YH6 A:23-174
    complexed with na
Human (Homo sapiens), E2 J2 [TaxId:9606] [143050] (1 PDB entry)
Uniprot Q5T7L1 12-168
ubc6 homologue
- Domains for 2f4w:
  1. Domain d2f4wa1: 2f4w A:12-168 [132958]
  2. Domain d2f4wb_: 2f4w B: [132959]
    automated match to d2f4wa1
Human (Homo sapiens), E2 L6 [TaxId:9606] [143052] (1 PDB entry)
Uniprot O14933 2-151
- Domain for 1wzv:
  - Domain d1wzva1: 1wzv A:2-151 [121529]
    Other proteins in same PDB: d1wzvb_

Human (Homo sapiens), E2 M [TaxId:9606] [143058] (2 PDB entries)
Uniprot P61081 27-183
the extra N-terminal peptide, bound to the heterodimeric E1 enzyme for NEDD8, can be seen in the PDB entry 1tt5, chains E and F

Domain for 1y8x:
- Domain d1y8xa1: 1y8x A:27-183 [122769]
  Other proteins in same PDB: d1y8xb1
Domain for 2nvu:
- Domain d2nvuc1: 2nvu C:3-183 [145698]
  Other proteins in same PDB: d2nvua_, d2nvub1, d2nvub2, d2nvui_, d2nvuj_
  complexed with atp, mg, zn

Human (Homo sapiens), E2 S [TaxId:9606] [143048] (1 PDB entry)
Uniprot Q16763 6-156
- Domain for 1zdn:
  - Domain d1zdna1: 1zdn A:6-156 [124943]
    Other proteins in same PDB: d1zdnb_
    complexed with na
Human (Homo sapiens), E2 T [TaxId:9606] [143057] (1 PDB entry)
Uniprot Q9NPD8 1-154
Hspc150
- Domain for 1yh2:
  - Domain d1yh2a1: 1yh2 A:1-154 [123158]
Human (Homo sapiens), E2 U [TaxId:9606] [143053] (1 PDB entry)
Uniprot Q5VVX9 1-148
- Domain for 1yrv:
  - Domain d1yrva1: 1yrv A:1-148 [123941]
Human (Homo sapiens), E2 variant 1 [TaxId:9606] [143051] (2 PDB entries)
Uniprot Q13404 80-221! Uniprot Q13404 82-220
1. Domain for 2a4d:
  - Domain d2a4da1: 2a4d A:82-220 [126152]
2. Domain for 2c2v:
  - Domain d2c2vc1: 2c2v C:33-174 [129687]
    Other proteins in same PDB: d2c2vb_, d2c2ve_, d2c2vf_, d2c2vh_, d2c2vi_, d2c2vk_, d2c2vl_, d2c2vs1, d2c2vt_, d2c2vu_, d2c2vv_
Human (Homo sapiens), mms2 [TaxId:9606] [64242] (3 PDB entries)
1. Domain for 1j74:
  - Domain d1j74a_: 1j74 A: [62672]
2. Domain for 1j7d:
  - Domain d1j7da_: 1j7d A: [62680]
    complexed with ubc13
3. Domain for 1zgu:
  - Domain d1zgua1: 1zgu A:12-150 [125061]
    Other proteins in same PDB: d1zgub1
    automatically matched to d1j7da_
Human (Homo sapiens), ubc13 [TaxId:9606] [64240] (1 PDB entry)
- Domain for 1j7d:
  - Domain d1j7db_: 1j7d B: [62681]
    complexed with Mms2
Human (Homo sapiens), ubc2b [TaxId:9606] [102840] (3 PDB entries)
E2-17 kDa
1. Domain for 1jas:
  - Domain d1jasa_: 1jas A: [90882]
2. Domain for 2yb6:
  - Domain d2yb6a_: 2yb6 A: [170720]
    automated match to d1jasa_
    complexed with bme, cl
3. Domain for 2ybf:
  - Domain d2ybfa_: 2ybf A: [170723]
    automated match to d1jasa_
    complexed with bme, na, so4
Human (Homo sapiens), ubc9 [TaxId:9606] [54503] (20 PDB entries)
identical sequence in many other species
1. Domain for 1a3s:
  - Domain d1a3sa_: 1a3s A: [38335]
2. Domains for 1kps:
  1. Domain d1kpsa_: 1kps A: [68786]
    Other proteins in same PDB: d1kpsb_, d1kpsd_
    complexed with so4
  2. Domain d1kpsc_: 1kps C: [68788]
    Other proteins in same PDB: d1kpsb_, d1kpsd_
    complexed with so4
3. Domain for 1u9a:
  - Domain d1u9aa_: 1u9a A: [38333]
    CASP2
4. Domain for 1u9b:
  - Domain d1u9ba_: 1u9b A: [38334]
5. Domain for 1z5s:
  - Domain d1z5sa1: 1z5s A:2-157 [124491]
    Other proteins in same PDB: d1z5sb1, d1z5sc1
    automatically matched to d1u9aa_
6. Domain for 2grn:
  - Domain d2grna_: 2grn A: [135568]
    Other proteins in same PDB: d2grnb1
    automated match to d1u9b__
7. Domain for 2gro:
  - Domain d2groa_: 2gro A: [161438]
    Other proteins in same PDB: d2grob_
    automated match to d1u9ba_
8. Domain for 2grp:
  - Domain d2grpa_: 2grp A: [161439]
    Other proteins in same PDB: d2grpb_
    automated match to d1u9ba_
9. Domain for 2grq:
  - Domain d2grqa_: 2grq A: [161440]
    Other proteins in same PDB: d2grqb_
    automated match to d1u9ba_
10. Domain for 2grr:
  - Domain d2grra_: 2grr A: [161441]
    Other proteins in same PDB: d2grrb_
    automated match to d1u9aa_
11. Domains for 2o25:
  1. Domain d2o25c_: 2o25 C: [138890]
    Other proteins in same PDB: d2o25a1, d2o25a2, d2o25b1, d2o25b2
    automated match to d1kpsa_
  2. Domain d2o25d_: 2o25 D: [138891]
    Other proteins in same PDB: d2o25a1, d2o25a2, d2o25b1, d2o25b2
    automated match to d1kpsa_
12. Domain for 2pe6:
  - Domain d2pe6a_: 2pe6 A: [139667]
    Other proteins in same PDB: d2pe6b_
    automated match to d1u9b__
13. Domain for 2px9:
  - Domain d2px9b1: 2px9 B:1-158 [149906]
    automatically matched to d1u9aa_
14. Domain for 2uyz:
  - Domain d2uyza1: 2uyz A:3-158 [145768]
    Other proteins in same PDB: d2uyzb1
    annotated as mouse protein in PDB
    complexed with na
15. Domain for 2vrr:
  - Domain d2vrra_: 2vrr A: [153522]
    Other proteins in same PDB: d2vrrb1
    automated match to d1a3sa_
    complexed with fmt, na
16. Domain for 2xwu:
  - Domain d2xwua_: 2xwu A: [170451]
    automated match to d1a3sa_
17. Domains for 3a4s:
  1. Domain d3a4sa_: 3a4s A: [171724]
    Other proteins in same PDB: d3a4sc_, d3a4sd_
    automated match to d1kpsa_
    protein/RNA complex
  2. Domain d3a4sb_: 3a4s B: [171725]
    Other proteins in same PDB: d3a4sc_, d3a4sd_
    automated match to d1kpsa_
    protein/RNA complex
18. Domain for 3uin:
  - Domain d3uina_: 3uin A: [186327]
    Other proteins in same PDB: d3uinc_
    automated match to d1a3sa_
19. Domain for 3uio:
  - Domain d3uioa_: 3uio A: [186329]
    Other proteins in same PDB: d3uioc_
    automated match to d1a3sa_
20. Domain for 3uip:
  - Domain d3uipa_: 3uip A: [186331]
    Other proteins in same PDB: d3uipc_
    automated match to d1a3sa_
Human (Homo sapiens), ubch10 [TaxId:9606] [64243] (1 PDB entry)
- Domains for 1i7k:
  1. Domain d1i7ka_: 1i7k A: [61889]
  2. Domain d1i7kb_: 1i7k B: [61890]
Human (Homo sapiens), ubch5b [TaxId:9606] [102841] (10 PDB entries)
Uniprot P62837
E2-17 kDa 2
1. Domain for 1ur6:
  - Domain d1ur6a_: 1ur6 A: [99811]
    Other proteins in same PDB: d1ur6b_
    complexed with zn
2. Domain for 1w4u:
  - Domain d1w4ua_: 1w4u A: [114194]
3. Domain for 2esk:
  - Domain d2eska_: 2esk A: [132326]
    automated match to d1ur6a_
4. Domain for 2eso:
  - Domain d2esoa1: 2eso A:1-147 [132341]
    mutant
5. Domain for 2esp:
  - Domain d2espa1: 2esp A:1-147 [132342]
    complexed with cl, mpd; mutant
6. Domain for 2esq:
  - Domain d2esqa1: 2esq A:1-147 [132343]
    mutant
7. Domain for 3l1y:
  - Domain d3l1ya_: 3l1y A: [179862]
    automated match to d1ur6a_
8. Domain for 4a49:
  - Domain d4a49b_: 4a49 B: [186719]
    automated match to d1ur6a_
    complexed with k, zn
9. Domain for 4a4b:
  - Domain d4a4bc_: 4a4b C: [186720]
    automated match to d1ur6a_
    complexed with ca, zn
10. Domain for 4a4c:
  - Domain d4a4cc_: 4a4c C: [186721]
    automated match to d1ur6a_
    complexed with ca, zn
Human (Homo sapiens), ubch7 [TaxId:9606] [54502] (2 PDB entries)
1. Domain for 1c4z:
  - Domain d1c4zd_: 1c4z D: [38331]
    Other proteins in same PDB: d1c4za_, d1c4zb_, d1c4zc_
2. Domain for 1fbv:
  - Domain d1fbvc_: 1fbv C: [38332]
    Other proteins in same PDB: d1fbva1, d1fbva2, d1fbva3, d1fbva4
    complexed with so4, zn
Human (Homo sapiens), ubch8 [TaxId:9606] [117850] (1 PDB entry)
Uniprot Q96LR5 54-201
- Domains for 1y6l:
  1. Domain d1y6la_: 1y6l A: [116509]
  2. Domain d1y6lb_: 1y6l B: [116510]
  3. Domain d1y6lc_: 1y6l C: [116511]
Leishmania major [TaxId:5664] [143049] (1 PDB entry)
Uniprot Q4Q5L3 9-166
Ubiquitin carrier protein 4, putative
- Domain for 1yf9:
  - Domain d1yf9a1: 1yf9 A:13-170 [123054]
    Other proteins in same PDB: d1yf9b_, d1yf9c_
    complexed with cl
Nematode (Caenorhabditis elegans), E2-19 kDa [TaxId:6239] [89862] (1 PDB entry)
- Domain for 1pzv:
  - Domain d1pzva_: 1pzv A: [88342]
Nematode (Caenorhabditis elegans), E2-21.5 kDa [TaxId:6239] [102842] (1 PDB entry)
- Domains for 1q34:
  1. Domain d1q34a_: 1q34 A: [95658]
  2. Domain d1q34b_: 1q34 B: [95659]
  3. Domain d1q34c_: 1q34 C: [95660]
Thale cress (Arabidopsis thaliana) [TaxId:3702] [54498] (1 PDB entry)
- Domain for 2aak:
  - Domain d2aaka_: 2aak A: [38325]
Toxoplasma gondii [TaxId:5811] [143059] (1 PDB entry)
- Domain for 2ayv:
  - Domain d2ayva1: 2ayv A:1-146 [127572]
    complexed with unx

More info for Protein Ubiquitin conjugating enzyme, UBC from d.20.1.1: UBC-related

Timeline for Protein Ubiquitin conjugating enzyme, UBC from d.20.1.1: UBC-related:

Protein Ubiquitin conjugating enzyme, UBC from d.20.1.1: UBC-related first appeared (with stable ids) in SCOP 1.55, called Protein Ubiquitin conjugating enzyme from d.20.1.1: Ubiquitin conjugating enzyme
Protein Ubiquitin conjugating enzyme, UBC from d.20.1.1: UBC-related appears in SCOPe 2.01
Protein Ubiquitin conjugating enzyme, UBC from d.20.1.1: UBC-related appears in SCOPe 2.03
Protein Ubiquitin conjugating enzyme, UBC from d.20.1.1: UBC-related appears in the current release, SCOPe 2.08