Lineage for Family d.20.1.1: UBC-related

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 857031Fold d.20: UBC-like [54494] (1 superfamily)
    alpha-beta(4)-alpha(3); core: meander beta-sheet plus one helix 2
  4. 857032Superfamily d.20.1: UBC-like [54495] (4 families) (S)
  5. 857033Family d.20.1.1: UBC-related [54496] (6 proteins)

Proteins:

  1. 857034Hypothetical protein Tgtwinscan_2721, E2 domain [143066] (1 species)
  2. 857038Putative ubiquitin-conjugating enzyme, E2 domain [143070] (1 species)
  3. 857041Ubiquitin conjugating enzyme, UBC [54497] (32 species)
    1. 857042Species Baker's yeast (Saccharomyces cerevisiae), mms2 [TaxId:4932] [64241] (2 PDB entries)
    2. 857045Species Baker's yeast (Saccharomyces cerevisiae), ubc1 [TaxId:4932] [69685] (3 PDB entries)
      Uniprot P21734
    3. 857050Species Baker's yeast (Saccharomyces cerevisiae), ubc13 [TaxId:4932] [64239] (3 PDB entries)
    4. 857055Species Baker's yeast (Saccharomyces cerevisiae), ubc2 (RAD6) [TaxId:4932] [54499] (1 PDB entry)
    5. 857059Species Baker's yeast (Saccharomyces cerevisiae), ubc4 [TaxId:4932] [54500] (1 PDB entry)
    6. 857061Species Baker's yeast (Saccharomyces cerevisiae), ubc7 [TaxId:4932] [54501] (1 PDB entry)
    7. 857063Species Caenorhabditis elegans, E2 2 [TaxId:6239] [143060] (1 PDB entry)
      Uniprot P35129 1-147
    8. 857065Species Clam (Spisula solidissima), E-2C [TaxId:6584] [54504] (1 PDB entry)
    9. 857067Species Human (Homo sapiens), E2 D3 [TaxId:9606] [143054] (2 PDB entries)
      Uniprot P61077 1-147
    10. 857073Species Human (Homo sapiens), E2 G1 [TaxId:9606] [143056] (1 PDB entry)
      Uniprot P62253 7-131
    11. 857075Species Human (Homo sapiens), E2 H [TaxId:9606] [143055] (1 PDB entry)
      Uniprot P62256 4-155
    12. 857078Species Human (Homo sapiens), E2 J2 [TaxId:9606] [143050] (1 PDB entry)
      Uniprot Q5T7L1 12-168
      ubc6 homologue
    13. 857081Species Human (Homo sapiens), E2 L6 [TaxId:9606] [143052] (2 PDB entries)
      Uniprot O14933 2-151
    14. 857085Species Human (Homo sapiens), E2 M [TaxId:9606] [143058] (2 PDB entries)
      Uniprot P61081 27-183
      the extra N-terminal peptide, bound to the heterodimeric E1 enzyme for NEDD8, can be seen in the PDB entry 1tt5, chains E and F
    15. 857088Species Human (Homo sapiens), E2 T [TaxId:9606] [143057] (1 PDB entry)
      Uniprot Q9NPD8 1-154
      Hspc150
    16. 857090Species Human (Homo sapiens), E2 U [TaxId:9606] [143053] (1 PDB entry)
      Uniprot Q5VVX9 1-148
    17. 857092Species Human (Homo sapiens), E2 variant 1 [TaxId:9606] [143051] (2 PDB entries)
      Uniprot Q13404 80-221! Uniprot Q13404 82-220
    18. 857098Species Human (Homo sapiens), mms2 [TaxId:9606] [64242] (3 PDB entries)
    19. 857102Species Human (Homo sapiens), ubc13 [TaxId:9606] [64240] (2 PDB entries)
    20. 857108Species Human (Homo sapiens), ubc2b [TaxId:9606] [102840] (1 PDB entry)
      E2-17 kDa
    21. 857110Species Human (Homo sapiens), ubc9 [TaxId:9606] [54503] (11 PDB entries)
      identical sequence in many other species
    22. 857124Species Human (Homo sapiens), ubch10 [TaxId:9606] [64243] (1 PDB entry)
    23. 857127Species Human (Homo sapiens), ubch5b [TaxId:9606] [102841] (8 PDB entries)
      Uniprot P62837
      E2-17 kDa 2
    24. 857142Species Human (Homo sapiens), ubch7 [TaxId:9606] [54502] (2 PDB entries)
    25. 857145Species Human (Homo sapiens), ubch8 [TaxId:9606] [117850] (1 PDB entry)
      Uniprot Q96LR5 54-201
    26. 857149Species Human(Homo sapiens), E2 S [TaxId:9606] [143048] (1 PDB entry)
      Uniprot Q16763 6-156
    27. 857152Species Leishmania major [TaxId:5664] [143049] (1 PDB entry)
      Uniprot Q4Q5L3 9-166
      Ubiquitin carrier protein 4, putative
    28. 857156Species Nematode (Caenorhabditis elegans), E2-19 kDa [TaxId:6239] [89862] (1 PDB entry)
    29. 857158Species Nematode (Caenorhabditis elegans), E2-21.5 kDa [TaxId:6239] [102842] (2 PDB entries)
    30. 857163Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [54498] (1 PDB entry)
    31. 857165Species Toxoplasma gondii [TaxId:5811] [143059] (1 PDB entry)
    32. 857167Species Xenopus laevis [TaxId:8355] [160080] (1 PDB entry)
  4. 857169Ubiquitin-conjugating enzyme E2 Q2, C-terminal domain [143068] (1 species)
    this proteins contains the N-terminal RWD domain
  5. 857172Ubiquitin-conjugating enzyme E2-25 kDa, E2 domain [143063] (2 species)
    ubc1 homologue; also contains the C-terminal UBA domain
    1. 857173Species Cow (Bos taurus) [TaxId:9913] [143065] (2 PDB entries)
      Uniprot P61085 1-154
    2. 857176Species Human (Homo sapiens) [TaxId:9606] [143064] (3 PDB entries)
      Uniprot P61086 1-156
  6. 857182Ubiquitin-protein ligase W (E2 W) [143061] (1 species)
    forms segment-swapped dimer

More info for Family d.20.1.1: UBC-related

Timeline for Family d.20.1.1: UBC-related: