Lineage for Family d.17.4.2: NTF2-like

  1. Root: SCOP 1.67
  2. 405194Class d: Alpha and beta proteins (a+b) [53931] (260 folds)
  3. 408884Fold d.17: Cystatin-like [54402] (7 superfamilies)
    Core: alpha-beta(4); helix packs against coiled antiparallel beta-sheet
  4. 409086Superfamily d.17.4: NTF2-like [54427] (10 families) (S)
    has a beta-alpha(2)-beta insertion after the main helix
  5. 409110Family d.17.4.2: NTF2-like [54431] (5 proteins)

Proteins:

  1. 409111mRNA transport regulator MTR2 [89849] (2 species)
    similar to p15; forms complex with MEX67 similar to the TAP-p15 complex
    1. 409112Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [89850] (1 PDB entry)
      Ykl186C
    2. 409114Species Yeast (Candida albicans) [TaxId:5476] [102809] (2 PDB entries)
  2. 409118NTF2-like domain of mRNA export factor MEX67 [89847] (2 species)
    similar to the TAP domain; forms complex with MTR2 similar to the TAP-p15 complex
    1. 409119Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [89848] (1 PDB entry)
      Ypl169C
    2. 409121Species Yeast (Candida albicans) [TaxId:5476] [102808] (1 PDB entry)
  3. 409124NTF2-like domain of Tip associating protein, TAP [69677] (1 species)
  4. 409128NTF2-related export protein 1 (p15) [69675] (1 species)
  5. 409132Nuclear transport factor-2 (NTF2) [54432] (3 species)
    1. 409133Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [75374] (2 PDB entries)
    2. 409142Species Human (Homo sapiens) [TaxId:9606] [75373] (1 PDB entry)
    3. 409145Species Rat (Rattus norvegicus) [TaxId:10116] [54433] (9 PDB entries)

More info for Family d.17.4.2: NTF2-like

Timeline for Family d.17.4.2: NTF2-like: