Lineage for Family d.17.4.2: NTF2-like

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2161468Fold d.17: Cystatin-like [54402] (7 superfamilies)
    Core: alpha-beta(4); helix packs against coiled antiparallel beta-sheet
  4. 2161993Superfamily d.17.4: NTF2-like [54427] (31 families) (S)
    has a beta-alpha(2)-beta insertion after the main helix
  5. 2162017Family d.17.4.2: NTF2-like [54431] (6 protein domains)

Protein Domains:

  1. 2162018mRNA transport regulator MTR2 [89849] (2 species)
    similar to p15; forms complex with MEX67 similar to the TAP-p15 complex
    1. 2162019Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [89850] (1 PDB entry)
      Ykl186C
    2. 2162021Species Yeast (Candida albicans) [TaxId:5476] [102809] (2 PDB entries)
  2. 2162025NTF2-like domain of mRNA export factor MEX67 [89847] (2 species)
    similar to the TAP domain; forms complex with MTR2 similar to the TAP-p15 complex
    1. 2162026Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [89848] (1 PDB entry)
      Ypl169C
    2. 2162028Species Yeast (Candida albicans) [TaxId:5476] [102808] (1 PDB entry)
  3. 2162031NTF2-like domain of Tip associating protein, TAP [69677] (1 species)
  4. 2162035NTF2-related export protein 1 (p15) [69675] (1 species)
  5. 2162039Nuclear transport factor-2 (NTF2) [54432] (4 species)
    1. 2162040Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [75374] (2 PDB entries)
    2. 2162049Species Cryptosporidium parvum [TaxId:5807] [159958] (1 PDB entry)
      Uniprot Q5CQI4 4-127
    3. 2162051Species Human (Homo sapiens) [TaxId:9606] [75373] (1 PDB entry)
    4. 2162054Species Norway rat (Rattus norvegicus) [TaxId:10116] [54433] (11 PDB entries)
      Uniprot P61972
  6. 2162079UBP3-associated protein BRE5 [159959] (1 species)

More info for Family d.17.4.2: NTF2-like

Timeline for Family d.17.4.2: NTF2-like: