SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family d.15.1.4: First domain of FERM

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2158219Fold d.15: beta-Grasp (ubiquitin-like) [54235] (14 superfamilies)
    core: beta(2)-alpha-beta(2); mixed beta-sheet 2143
  4. 2158220Superfamily d.15.1: Ubiquitin-like [54236] (11 families) (S)
  5. 2159242Family d.15.1.4: First domain of FERM [54256] (6 protein domains)

Protein Domains:

  1. 2159243Erythroid membrane protein 4.1R [54261] (1 species)
  2. 2159248Ezrin [82581] (1 species)
  3. 2159252Focal adhesion kinase 1 [142960] (1 species)
  4. 2159258Merlin [69660] (2 species)
    the neurofibromatosis 2 tumor suppressor protein
    1. 2159259Species Human (Homo sapiens) [TaxId:9606] [69661] (1 PDB entry)
    2. 2159262Species Mouse (Mus musculus) [TaxId:10090] [75361] (1 PDB entry)
  5. 2159264Moesin [54257] (2 species)
    1. 2159265Species Human (Homo sapiens) [TaxId:9606] [54258] (3 PDB entries)
      Uniprot P26038 4-297
    2. 2159270Species Mouse (Mus musculus) [TaxId:10090] [311111] (1 PDB entry)
  6. 2159272Radixin [54259] (1 species)

More info for Family d.15.1.4: First domain of FERM

Timeline for Family d.15.1.4: First domain of FERM: