SCOPe 2.02: Family d.14.1.4: Ribonuclease PH domain 1-like

Lineage for Family d.14.1.4: Ribonuclease PH domain 1-like

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.14: Ribosomal protein S5 domain 2-like [54210] (1 superfamily)
   core: beta(3)-alpha-beta-alpha; 2 layers: alpha/beta; left-handed crossover

4. Superfamily d.14.1: Ribosomal protein S5 domain 2-like [54211] (13 families)

5. Family d.14.1.4: Ribonuclease PH domain 1-like [54229] (10 proteins)

Proteins:

1. Exosome complex exonuclease 1, ECX1 [159923] (2 species)

   1. Species Archaeoglobus fulgidus [TaxId:2234] [159925] (2 PDB entries)
      Uniprot O29757 10-153

   2. Species Sulfolobus solfataricus [TaxId:2287] [159924] (7 PDB entries)
      Uniprot Q9UXC2 8-155

2. Exosome complex exonuclease 2,ECX2 [159920] (2 species)

   1. Species Archaeoglobus fulgidus [TaxId:2234] [159921] (2 PDB entries)
      Uniprot O29756 3-178

   2. Species Sulfolobus solfataricus [TaxId:2287] [159922] (7 PDB entries)
      Uniprot Q9UXC0 1-191

3. Exosome complex exonuclease MTR3 [159916] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [159917] (1 PDB entry)
     Uniprot Q5RKV6 29-175

4. Exosome complex exonuclease RRP41 [159918] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [159919] (1 PDB entry)
     Uniprot Q9NPD3 7-151

5. Exosome complex exonuclease RRP42 [159908] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [159909] (1 PDB entry)
     Uniprot Q15024 5-191

6. Exosome complex exonuclease RRP43 [159914] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [159915] (1 PDB entry)
     Uniprot Q96B26 7-187

7. Exosome complex exonuclease RRP45 [159912] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [159913] (1 PDB entry)
     Uniprot Q86Y41 1-184

8. Exosome complex exonuclease RRP46 [159910] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [159911] (1 PDB entry)
     Uniprot Q9NQT4 25-146

9. Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4 [54230] (1 species)
   duplication of two-domain units formed by domains 1-2 and 4-5

   • Species Streptomyces antibioticus [TaxId:1890] [54231] (2 PDB entries)

10. Ribonuclease PH, domain 1 [102758] (3 species)

    1. Species Aquifex aeolicus [TaxId:63363] [102759] (4 PDB entries)

    2. Species Bacillus subtilis [TaxId:1423] [102761] (3 PDB entries)

    3. Species Pseudomonas aeruginosa [TaxId:287] [102760] (2 PDB entries)

More info for Family d.14.1.4: Ribonuclease PH domain 1-like

Timeline for Family d.14.1.4: Ribonuclease PH domain 1-like:

• Family d.14.1.4: Ribonuclease PH domain 1-like first appeared (with stable ids) in SCOP 1.55, called Family d.14.1.4: Polynucleotide phosporylase/guanosine pentaphospate synthase (PNPase/GPSI), domains 1 and 4
  
• Family d.14.1.4: Ribonuclease PH domain 1-like appears in SCOPe 2.01
  
• Family d.14.1.4: Ribonuclease PH domain 1-like appears in SCOPe 2.03
  
• Family d.14.1.4: Ribonuclease PH domain 1-like appears in the current release, SCOPe 2.08