Lineage for Protein: Histidine triad nucleotide-binding protein (HINT)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2499927Fold d.13: HIT-like [54196] (2 superfamilies)
    alpha-beta(3)-alpha-beta(2); 3 layers: alpha/beta/alpha
  4. 2499928Superfamily d.13.1: HIT-like [54197] (6 families) (S)
  5. 2499929Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins [54198] (8 protein domains)
    Pfam PF01230
    topologically similar to the N-terminal domain of protein kinases
  6. 2499940Protein Histidine triad nucleotide-binding protein (HINT) [54199] (2 species)

Species:

  1. 2499941Human (Homo sapiens) [TaxId:9606] [224916] (19 PDB entries)
    1. Domains for 4eqe:
      1. 2499960Domain d4eqea_: 4eqe A: [195461]
        automated match to d3tw2a_
        complexed with epe, kaa
      2. 2499961Domain d4eqeb_: 4eqe B: [195460]
        automated match to d3tw2a_
        complexed with epe, kaa
    2. Domains for 4eqg:
      1. 2499958Domain d4eqga_: 4eqg A: [195463]
        automated match to d3tw2a_
        complexed with a5a, epe
      2. 2499959Domain d4eqgb_: 4eqg B: [195462]
        automated match to d3tw2a_
        complexed with a5a, epe
    3. Domains for 4eqh:
      1. 2499977Domain d4eqha_: 4eqh A: [201947]
        automated match to d4eqeb_
        complexed with epe, wsa
      2. 2499978Domain d4eqhb_: 4eqh B: [195464]
        automated match to d3tw2a_
        complexed with epe, wsa
    4. Domains for 5i2e:
      1. 2499971Domain d5i2ea_: 5i2e A: [318865]
        automated match to d3tw2a_
        complexed with 67d, gol
      2. 2499972Domain d5i2eb_: 5i2e B: [318843]
        automated match to d3tw2a_
        complexed with 67d, gol
    5. Domains for 5i2f:
      1. 2499946Domain d5i2fa_: 5i2f A: [318771]
        automated match to d3tw2a_
        complexed with bs5, edo
      2. 2499947Domain d5i2fb_: 5i2f B: [318772]
        automated match to d3tw2a_
        complexed with bs5, edo
    6. Domains for 5ipb:
      1. 2499966Domain d5ipba_: 5ipb A: [330992]
        automated match to d3tw2a_
        complexed with cl; mutant
      2. 2499967Domain d5ipbb_: 5ipb B: [331047]
        automated match to d3tw2a_
        complexed with cl; mutant
    7. Domains for 5ipc:
      1. 2499948Domain d5ipca_: 5ipc A: [336451]
        automated match to d3tw2a_
        complexed with 6ce, cl, edo; mutant
      2. 2499949Domain d5ipcb_: 5ipc B: [336454]
        automated match to d3tw2a_
        complexed with 6ce, cl, edo; mutant
    8. Domains for 5ipd:
      1. 2499979Domain d5ipda_: 5ipd A: [336533]
        automated match to d3tw2a_
        complexed with 6cg
      2. 2499980Domain d5ipdb_: 5ipd B: [336446]
        automated match to d3tw2a_
        complexed with 6cg
    9. Domains for 5kly:
      1. 2499950Domain d5klya_: 5kly A: [336048]
        automated match to d3tw2a_
        complexed with 6ur, cl, peg; mutant
      2. 2499951Domain d5klyb_: 5kly B: [336031]
        automated match to d3tw2a_
        complexed with 6ur, cl, peg; mutant
    10. Domains for 5klz:
      1. 2499956Domain d5klza_: 5klz A: [335976]
        automated match to d3tw2a_
        complexed with amp, edo
      2. 2499957Domain d5klzb_: 5klz B: [336013]
        automated match to d3tw2a_
        complexed with amp, edo
    11. Domains for 5km0:
      1. 2499962Domain d5km0a_: 5km0 A: [336052]
        automated match to d3tw2a_
        complexed with imp
      2. 2499963Domain d5km0b_: 5km0 B: [336152]
        automated match to d3tw2a_
        complexed with imp
      3. 2499964Domain d5km0c_: 5km0 C: [336000]
        automated match to d3tw2a_
        complexed with imp
      4. 2499965Domain d5km0d_: 5km0 D: [336047]
        automated match to d3tw2a_
        complexed with imp
    12. Domains for 5km1:
      1. 2499975Domain d5km1a_: 5km1 A: [336095]
        automated match to d3tw2a_
        complexed with 5gp, edo
      2. 2499976Domain d5km1b_: 5km1 B: [336063]
        automated match to d3tw2a_
        complexed with 5gp, edo
    13. Domains for 5km2:
      1. 2499944Domain d5km2a_: 5km2 A: [336087]
        automated match to d3tw2a_
        complexed with c5p, cl, gol
      2. 2499945Domain d5km2b_: 5km2 B: [336135]
        automated match to d3tw2a_
        complexed with c5p, cl, gol
    14. Domains for 5km3:
      1. 2499942Domain d5km3a_: 5km3 A: [335998]
        automated match to d3tw2a_
        complexed with gol, u5p
      2. 2499943Domain d5km3b_: 5km3 B: [336044]
        automated match to d3tw2a_
        complexed with gol, u5p
    15. Domains for 5km4:
      1. 2499954Domain d5km4a_: 5km4 A: [335990]
        automated match to d3tw2a_
        complexed with iu
      2. 2499955Domain d5km4b_: 5km4 B: [336004]
        automated match to d3tw2a_
        complexed with iu
    16. Domain for 5km6:
    17. Domains for 5kma:
      1. 2499968Domain d5kmaa_: 5kma A: [336045]
        automated match to d3tw2a_
        complexed with 777, cl; mutant
      2. 2499969Domain d5kmab_: 5kma B: [336069]
        automated match to d3tw2a_
        complexed with 777, cl; mutant
    18. Domains for 5kmb:
      1. 2499973Domain d5kmba_: 5kmb A: [335984]
        automated match to d3tw2a_
        complexed with 6ut, cl; mutant
      2. 2499974Domain d5kmbb_: 5kmb B: [336042]
        automated match to d3tw2a_
        complexed with 6ut, cl; mutant
    19. Domains for 5kmc:
      1. 2499952Domain d5kmca_: 5kmc A: [336005]
        automated match to d3tw2a_
        complexed with 6uu
      2. 2499953Domain d5kmcb_: 5kmc B: [336039]
        automated match to d3tw2a_
        complexed with 6uu
  2. 2499981Rabbit (Oryctolagus cuniculus) [TaxId:9986] [54200] (10 PDB entries)
    1. Domain for 1rzy:
    2. Domain for 3llj:
    3. Domain for 3o1c:
    4. Domain for 3o1x:
    5. Domain for 3o1z:
    6. Domain for 3qgz:
    7. Domain for 3rhn:
    8. Domain for 4rhn:
    9. Domain for 5rhn:
    10. Domain for 6rhn:

More info for Protein Histidine triad nucleotide-binding protein (HINT) from d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins

Timeline for Protein Histidine triad nucleotide-binding protein (HINT) from d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins:

  • Protein Histidine triad nucleotide-binding protein (HINT) from d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins first appeared (with stable ids) in SCOP 1.55
  • Protein Histidine triad nucleotide-binding protein (HINT) from d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins appears in SCOPe 2.06