SCOPe 2.06: Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins

Lineage for Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.13: HIT-like [54196] (2 superfamilies)
   alpha-beta(3)-alpha-beta(2); 3 layers: alpha/beta/alpha

4. Superfamily d.13.1: HIT-like [54197] (5 families)

5. Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins [54198] (8 proteins)
   Pfam PF01230
   topologically similar to the N-terminal domain of protein kinases

Proteins:

1. FHIT (fragile histidine triad protein) [54201] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54202] (8 PDB entries)

2. Histidine triad nucleotide-binding protein (HINT) [54199] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [224916] (3 PDB entries)

   2. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [54200] (10 PDB entries)

3. Histidine triad protein Mfla2506 [159880] (1 species)

   • Species Methylobacillus flagellatus [TaxId:405] [159881] (1 PDB entry)
     Uniprot Q1GYB6 6-144

4. Hit [117789] (1 species)

   • Species Bacillus subtilis [TaxId:1423] [117790] (1 PDB entry)
     Uniprot O07513

5. NIT-FHIT fusion protein, C-terminal domain [54205] (1 species)

   • Species Nematode (Caenorhabditis elegans) [TaxId:6239] [54206] (1 PDB entry)

6. Protein kinase C inhibitor-1, PKCI-1 [54203] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54204] (6 PDB entries)

7. Putative hydrolase [117791] (2 species)

   1. Species Clostridium thermocellum [TaxId:1515] [117792] (1 PDB entry)
      Uniprot Q4CCR3

   2. Species Ruminiclostridium thermocellum [TaxId:637887] [332789] (1 PDB entry)

8. automated matches [191082] (2 species)
   not a true protein

   1. Species Bacillus anthracis [TaxId:261594] [189022] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [189791] (38 PDB entries)

More info for Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins

Timeline for Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins:

• Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins first appeared (with stable ids) in SCOP 1.55
  
• Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins appears in SCOPe 2.05
  
• Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins appears in SCOPe 2.07
  
• Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins appears in the current release, SCOPe 2.08