SCOP 1.69: Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins

Lineage for Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins

1. Root: SCOP 1.69

2. Class d: Alpha and beta proteins (a+b) [53931] (279 folds)

3. Fold d.13: HIT-like [54196] (2 superfamilies)
   alpha-beta(3)-alpha-beta(2); 3 layers: alpha/beta/alpha

4. Superfamily d.13.1: HIT-like [54197] (3 families)

5. Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins [54198] (4 proteins)
   topologically similar to the N-terminal domain of protein kinases

Proteins:

1. FHIT (fragile histidine triad protein) [54201] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54202] (8 PDB entries)

2. Histidine triad nucleotide-binding protein (HINT) [54199] (1 species)

   • Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [54200] (5 PDB entries)

3. NIT-FHIT fusion protein, C-terminal domain [54205] (1 species)

   • Species Nematode (Caenorhabditis elegans) [TaxId:6239] [54206] (1 PDB entry)

4. Protein kinase C inhibitor-1, PKCI-1 [54203] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54204] (6 PDB entries)

More info for Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins

Timeline for Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins:

• Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins first appeared (with stable ids) in SCOP 1.55
  
• Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins appears in SCOP 1.67
  
• Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins appears in SCOP 1.71
  
• Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins appears in the current release, SCOPe 2.08