SCOP 1.67: Family d.10.1.3: Methyl-CpG-binding domain, MBD

Lineage for Family d.10.1.3: Methyl-CpG-binding domain, MBD

1. Root: SCOP 1.67

2. Class d: Alpha and beta proteins (a+b) [53931] (260 folds)

3. Fold d.10: DNA-binding domain [54170] (1 superfamily)
   beta(3)-alpha; 2 layers: alpha/beta

4. Superfamily d.10.1: DNA-binding domain [54171] (4 families)

5. Family d.10.1.3: Methyl-CpG-binding domain, MBD [54178] (2 proteins)

Proteins:

1. Methyl-CpG-binding protein 2, MECP2 [54179] (2 species)

   1. Species Chicken (Gallus gallus) [TaxId:9031] [102734] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [54180] (1 PDB entry)

2. Methylation-dependent transcriptional repressor MBD1/PCM1 [54181] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54182] (2 PDB entries)

More info for Family d.10.1.3: Methyl-CpG-binding domain, MBD

Timeline for Family d.10.1.3: Methyl-CpG-binding domain, MBD:

• Family d.10.1.3: Methyl-CpG-binding domain, MBD first appeared (with stable ids) in SCOP 1.55
  
• Family d.10.1.3: Methyl-CpG-binding domain, MBD appears in SCOP 1.65
  
• Family d.10.1.3: Methyl-CpG-binding domain, MBD appears in SCOP 1.69
  
• Family d.10.1.3: Methyl-CpG-binding domain, MBD appears in the current release, SCOPe 2.08