Lineage for Family b.34.13.2: Chromo domain

  1. Root: SCOPe 2.06
  2. 2021373Class b: All beta proteins [48724] (177 folds)
  3. 2053585Fold b.34: SH3-like barrel [50036] (21 superfamilies)
    barrel, partly opened; n*=4, S*=8; meander
    the last strand is interrupted by a turn of 3-10 helix
  4. 2055542Superfamily b.34.13: Chromo domain-like [54160] (4 families) (S)
    SH3-like barrel is capped by a C-terminal helix
  5. 2055586Family b.34.13.2: Chromo domain [54165] (8 proteins)
    lacks the SH3-like barrel first strand that can be complemented by bound peptide ligand; in shadow chromo domain the corresponding site is altered by insertion; similarity to the IL8-like fold

Proteins:

  1. 2055587ATP-dependent helicase CHD1 (Chromo domain protein 1) [141220] (2 species)
    1. 2055588Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [141222] (2 PDB entries)
      Uniprot P32657 172-252! Uniprot P32657 249-347
    2. 2055591Species Human (Homo sapiens) [TaxId:9606] [141221] (5 PDB entries)
      Uniprot O14646 269-366! Uniprot O14646 270-355! Uniprot O14646 366-445! Uniprot O14646 367-443! Uniprot O14646 367-445
  2. 2055617Chromobox protein homolog 8 [141214] (1 species)
    Polycomb 3 homolog, Pc3
  3. 2055620Chromodomain protein, Y-like isoform [141218] (1 species)
  4. 2055623CpSRP43 [141216] (1 species)
    Signal recognition particle 43 kDa protein, chloroplast precursor (CAO)
  5. 2055631Heterochromatin protein 1, HP1 [54166] (4 species)
    duplication: consists of two homologous domains, N-terminal chromo domain and C-terminal chromo shadow domain
    1. 2055632Species Fission yeast (Schizosaccharomyces pombe), SWI6 [TaxId:4896] [54169] (1 PDB entry)
    2. 2055635Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [75343] (3 PDB entries)
      Uniprot P05205 23-74
    3. 2055639Species Human (Homo sapiens) [TaxId:9606] [187099] (3 PDB entries)
    4. 2055649Species Mouse (Mus musculus), HP1 beta (MOD1, M31) [TaxId:10090] [54167] (4 PDB entries)
  6. 2055656Histone methyltransferase clr4, chromo domain [64217] (1 species)
  7. 2055659Polycomb protein, Pc [101688] (1 species)
  8. 2055663automated matches [191035] (3 species)
    not a true protein
    1. 2055664Species Human (Homo sapiens) [TaxId:9606] [188859] (13 PDB entries)
    2. 2055688Species Mouse (Mus musculus) [TaxId:10090] [255382] (5 PDB entries)
    3. 2055701Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [279724] (2 PDB entries)

More info for Family b.34.13.2: Chromo domain

Timeline for Family b.34.13.2: Chromo domain: