Lineage for Family d.9.1.1: Interleukin 8-like chemokines

  1. Root: SCOP 1.63
  2. 251695Class d: Alpha and beta proteins (a+b) [53931] (224 folds)
  3. 253528Fold d.9: IL8-like [54116] (2 superfamilies)
    beta(3)-alpha
  4. 253529Superfamily d.9.1: Interleukin 8-like chemokines [54117] (1 family) (S)
    form dimers with different dimerisation modes
  5. 253530Family d.9.1.1: Interleukin 8-like chemokines [54118] (23 proteins)

Proteins:

  1. 253531CC chemokine I-309 [54138] (1 species)
  2. 253534Chemokine domain of fractalkine [54146] (1 species)
  3. 253541Chemokine hcc-2 (macrophage inflammatory protein-5) [54154] (1 species)
  4. Cytokine-induced neutrophil chemoattractant, CINC/Gro [54158] (1 species)
  5. 253547Eotaxin [54140] (1 species)
  6. 253551Eotaxin-2 [54142] (1 species)
  7. 253555Eotaxin-3 [75341] (1 species)
  8. 253559Gro beta [54156] (1 species)
  9. 253563IL-8/MGSA chimeric protein CIL-8M [54126] (1 species)
    IL-8: residues 1-53; MGSA: residues 54-72
  10. 253567Interleukin-8, IL-8 [54119] (1 species)
  11. 253586IP-10/CXCL10 [82573] (1 species)
  12. 253589Lymphotactin [69632] (1 species)
  13. 253593Macrophage inflammatory protein, MIP [54128] (5 species)
    has different dimerisation mode
    1. 253594Species Human (Homo sapiens), 1-alpha [TaxId:9606] [54130] (2 PDB entries)
    2. 253599Species Human (Homo sapiens), 1-beta [TaxId:9606] [54129] (3 PDB entries)
    3. 253605Species Human (Homo sapiens), ccl20/mip-3a [TaxId:9606] [75340] (1 PDB entry)
    4. 253608Species Kaposi's sarcoma herpes virus, VMIP-II [54131] (4 PDB entries)
      anti-HIV chemokine
    5. 253614Species Mouse (Mus musculus), ccl20/mip-3a [TaxId:10090] [64214] (1 PDB entry)
  14. 253616Macrophage inflammatory protein-2 [54152] (1 species)
  15. 253620Melanoma growth stimulating activity (MGSA) [54124] (1 species)
  16. 253628Monocyte chemoattractant protein-1 (MCP-1, MCAF) [54134] (1 species)
  17. 253638Monocyte chemoattractant protein-2 (MCP-2) [54136] (1 species)
  18. 253641Monocyte chemoattractant protein-3 (MCP-3) [54144] (1 species)
  19. 253646Myeloid progenitor inhibitory factor-1 (MPIF-1) [64215] (1 species)
  20. 253649Neutrophil-activating peptide-2 (NAP-2) [54148] (1 species)
  21. 253659Platelet factor 4, PF4 [54121] (2 species)
    1. 253660Species Cow (Bos taurus) [TaxId:9913] [54122] (1 PDB entry)
    2. 253665Species Human (Homo sapiens) [TaxId:9606] [54123] (3 PDB entries)
  22. 253678RANTES (regulated upon activation, normal T-cell expressed and secreted) [54132] (1 species)
    has different dimerisation mode
  23. 253690Stromal cell-derived factor-1 (SDF-1) [54150] (1 species)

More info for Family d.9.1.1: Interleukin 8-like chemokines

Timeline for Family d.9.1.1: Interleukin 8-like chemokines: