SCOPe 2.03: Family d.5.1.1: Ribonuclease A-like

Lineage for Family d.5.1.1: Ribonuclease A-like

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.5: RNase A-like [54075] (1 superfamily)
   contains long curved beta-sheet and 3 helices

4. Superfamily d.5.1: RNase A-like [54076] (2 families)
   can be classified as disulfide-rich

5. Family d.5.1.1: Ribonuclease A-like [54077] (9 proteins)

Proteins:

1. Amphibian cytotoxic ribonuclease [54084] (5 species)

   1. Species Bullfrog (Rana catesbeiana) [TaxId:8400] [54085] (4 PDB entries)

   2. Species Bullfrog (Rana catesbeiana), RNase2 [TaxId:8400] [82571] (1 PDB entry)

   3. Species Bullfrog (Rana catesbeiana), RNase4 [TaxId:8400] [75339] (1 PDB entry)

   4. Species Bullfrog (Rana catesbeiana), RNase6 [TaxId:8400] [110781] (2 PDB entries)
      Uniprot Q9DFY5

   5. Species Frog (Rana pipiens), P-30 [TaxId:8404] [54083] (10 PDB entries)

2. Angiogenin [54094] (2 species)

   1. Species Cow (Bos taurus) [TaxId:9913] [54096] (2 PDB entries)

   2. Species Human (Homo sapiens) [TaxId:9606] [54095] (30 PDB entries)

3. Eosinophil cationic protein (ECP), ribonuclease 3 [54090] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54091] (5 PDB entries)

4. Eosinophil-derived neurotoxin (EDN) [64205] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [64206] (11 PDB entries)

5. Hybrid between ribonuclease A and seminal ribonuclease [54088] (1 species)

   • Species Cow (Bos taurus) [TaxId:9913] [54089] (1 PDB entry)

6. Ribonuclease 4 [54092] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [54093] (2 PDB entries)

7. Ribonuclease A (also ribonuclease B, S) [54078] (3 species)

   1. Species Cow (Bos taurus) [TaxId:9913] [54079] (164 PDB entries)

   2. Species Human (Homo sapiens), des1-7 [TaxId:9606] [54080] (8 PDB entries)

   3. Species Norway rat (Rattus norvegicus) [TaxId:10116] [54081] (1 PDB entry)

8. Seminal ribonucleasease [54086] (1 species)

   • Species Cow (Bos taurus) [TaxId:9913] [54087] (16 PDB entries)
     Uniprot P00669 27-150

9. automated matches [190061] (4 species)
   not a true protein

   1. Species Cow (Bos taurus) [TaxId:9913] [186780] (70 PDB entries)

   2. Species Frog (Rana pipiens) [TaxId:8404] [188156] (3 PDB entries)

   3. Species Human (Homo sapiens) [TaxId:9606] [186903] (6 PDB entries)

   4. Species Mouse (Mus musculus) [TaxId:10090] [187495] (5 PDB entries)

More info for Family d.5.1.1: Ribonuclease A-like

Timeline for Family d.5.1.1: Ribonuclease A-like:

• Family d.5.1.1: Ribonuclease A-like first appeared (with stable ids) in SCOP 1.55
  
• Family d.5.1.1: Ribonuclease A-like appears in SCOPe 2.02
  
• Family d.5.1.1: Ribonuclease A-like appears in SCOPe 2.04
  
• Family d.5.1.1: Ribonuclease A-like appears in the current release, SCOPe 2.08