SCOPe 2.02: Family d.4.1.2: DNA/RNA non-specific endonuclease

Lineage for Family d.4.1.2: DNA/RNA non-specific endonuclease

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.4: His-Me finger endonucleases [54059] (1 superfamily)
   core: (alpha)-beta-omega_loop-beta-alpha; embeded in larger different structures

4. Superfamily d.4.1: His-Me finger endonucleases [54060] (6 families)
   common motif contains conserved histidine residue and metal-binding site

5. Family d.4.1.2: DNA/RNA non-specific endonuclease [54066] (2 proteins)
   the core motif is inserted in a six-stranded meander beta-sheet domain

Proteins:

1. Nuclease NucA [159863] (1 species)

   • Species Nostoc sp. PCC 7120 [TaxId:103690] [159864] (2 PDB entries)
     Uniprot P38446 35-274

2. Sm endonuclease [54067] (1 species)

   • Species Serratia marcescens [TaxId:615] [54068] (5 PDB entries)

More info for Family d.4.1.2: DNA/RNA non-specific endonuclease

Timeline for Family d.4.1.2: DNA/RNA non-specific endonuclease:

• Family d.4.1.2: DNA/RNA non-specific endonuclease first appeared (with stable ids) in SCOP 1.55, called Family d.4.1.2: Sm endonuclease
  
• Family d.4.1.2: DNA/RNA non-specific endonuclease appears in SCOPe 2.01
  
• Family d.4.1.2: DNA/RNA non-specific endonuclease appears in SCOPe 2.03
  
• Family d.4.1.2: DNA/RNA non-specific endonuclease appears in the current release, SCOPe 2.08