SCOPe 2.04: Protein: Transglutaminase catalytic domain

Lineage for Protein: Transglutaminase catalytic domain

Root: SCOPe 2.04
Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
Fold d.3: Cysteine proteinases [54000] (1 superfamily)
consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

Superfamily d.3.1: Cysteine proteinases [54001] (23 families)

(S)

the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

Family d.3.1.4: Transglutaminase core [54044] (3 proteins)
Protein Transglutaminase catalytic domain [54045] (4 species)

Species:

Human (Homo sapiens), blood isozyme [TaxId:9606] [54046] (8 PDB entries)
Coagulation factor XIII
1. Domains for 1evu:
  1. Domain d1evua4: 1evu A:191-508 [37113]
    Other proteins in same PDB: d1evua1, d1evua2, d1evua3, d1evub1, d1evub2, d1evub3
    complexed with ca, pgo
  2. Domain d1evub4: 1evu B:191-508 [37114]
    Other proteins in same PDB: d1evua1, d1evua2, d1evua3, d1evub1, d1evub2, d1evub3
    complexed with ca, pgo
2. Domains for 1ex0:
  1. Domain d1ex0a4: 1ex0 A:191-510 [90468]
    Other proteins in same PDB: d1ex0a1, d1ex0a2, d1ex0a3, d1ex0b1, d1ex0b2, d1ex0b3
    complexed with ca, pgo, po4; mutant
  2. Domain d1ex0b4: 1ex0 B:191-511 [90472]
    Other proteins in same PDB: d1ex0a1, d1ex0a2, d1ex0a3, d1ex0b1, d1ex0b2, d1ex0b3
    complexed with ca, pgo, po4; mutant
3. Domains for 1f13:
  1. Domain d1f13a4: 1f13 A:191-515 [37107]
    Other proteins in same PDB: d1f13a1, d1f13a2, d1f13a3, d1f13b1, d1f13b2, d1f13b3
  2. Domain d1f13b4: 1f13 B:191-515 [37108]
    Other proteins in same PDB: d1f13a1, d1f13a2, d1f13a3, d1f13b1, d1f13b2, d1f13b3
4. Domains for 1fie:
  1. Domain d1fiea4: 1fie A:191-515 [37109]
    Other proteins in same PDB: d1fiea1, d1fiea2, d1fiea3, d1fieb1, d1fieb2, d1fieb3
  2. Domain d1fieb4: 1fie B:191-515 [37110]
    Other proteins in same PDB: d1fiea1, d1fiea2, d1fiea3, d1fieb1, d1fieb2, d1fieb3
5. Domains for 1ggt:
  1. Domain d1ggta4: 1ggt A:191-515 [37111]
    Other proteins in same PDB: d1ggta1, d1ggta2, d1ggta3, d1ggtb1, d1ggtb2, d1ggtb3
  2. Domain d1ggtb4: 1ggt B:191-515 [37112]
    Other proteins in same PDB: d1ggta1, d1ggta2, d1ggta3, d1ggtb1, d1ggtb2, d1ggtb3
6. Domains for 1ggu:
  1. Domain d1ggua4: 1ggu A:191-508 [37115]
    Other proteins in same PDB: d1ggua1, d1ggua2, d1ggua3, d1ggub1, d1ggub2, d1ggub3
    complexed with ca
  2. Domain d1ggub4: 1ggu B:191-508 [37116]
    Other proteins in same PDB: d1ggua1, d1ggua2, d1ggua3, d1ggub1, d1ggub2, d1ggub3
    complexed with ca
7. Domains for 1ggy:
  1. Domain d1ggya4: 1ggy A:191-508 [37117]
    Other proteins in same PDB: d1ggya1, d1ggya2, d1ggya3, d1ggyb1, d1ggyb2, d1ggyb3
    complexed with yb
  2. Domain d1ggyb4: 1ggy B:191-508 [37118]
    Other proteins in same PDB: d1ggya1, d1ggya2, d1ggya3, d1ggyb1, d1ggyb2, d1ggyb3
    complexed with yb
8. Domains for 1qrk:
  1. Domain d1qrka4: 1qrk A:191-511 [37119]
    Other proteins in same PDB: d1qrka1, d1qrka2, d1qrka3, d1qrkb1, d1qrkb2, d1qrkb3
    complexed with sr
  2. Domain d1qrkb4: 1qrk B:191-507 [37120]
    Other proteins in same PDB: d1qrka1, d1qrka2, d1qrka3, d1qrkb1, d1qrkb2, d1qrkb3
    complexed with sr
Human (Homo sapiens), TGase E3 [TaxId:9606] [75334] (5 PDB entries)
1. Domains for 1l9m:
  1. Domain d1l9ma4: 1l9m A:141-461 [73735]
    Other proteins in same PDB: d1l9ma1, d1l9ma2, d1l9ma3, d1l9mb1, d1l9mb2, d1l9mb3
    complexed with br, ca, cl
  2. Domain d1l9mb4: 1l9m B:141-460 [73739]
    Other proteins in same PDB: d1l9ma1, d1l9ma2, d1l9ma3, d1l9mb1, d1l9mb2, d1l9mb3
    complexed with br, ca, cl
2. Domains for 1l9n:
  1. Domain d1l9na4: 1l9n A:141-460 [73743]
    Other proteins in same PDB: d1l9na1, d1l9na2, d1l9na3, d1l9nb1, d1l9nb2, d1l9nb3
    complexed with bgl, ca, cl
  2. Domain d1l9nb4: 1l9n B:141-460 [73747]
    Other proteins in same PDB: d1l9na1, d1l9na2, d1l9na3, d1l9nb1, d1l9nb2, d1l9nb3
    complexed with bgl, ca, cl
3. Domains for 1nud:
  1. Domain d1nuda4: 1nud A:141-460 [86177]
    Other proteins in same PDB: d1nuda1, d1nuda2, d1nuda3, d1nudb1, d1nudb2, d1nudb3
    complexed with br, ca, cl
  2. Domain d1nudb4: 1nud B:141-460 [86181]
    Other proteins in same PDB: d1nuda1, d1nuda2, d1nuda3, d1nudb1, d1nudb2, d1nudb3
    complexed with br, ca, cl
4. Domain for 1nuf:
  - Domain d1nufa4: 1nuf A:141-461 [86185]
    Other proteins in same PDB: d1nufa1, d1nufa2, d1nufa3
    complexed with br, ca, cl
5. Domains for 1nug:
  1. Domain d1nuga4: 1nug A:141-461 [86189]
    Other proteins in same PDB: d1nuga1, d1nuga2, d1nuga3, d1nugb1, d1nugb2, d1nugb3
    complexed with ca, cl, mg
  2. Domain d1nugb4: 1nug B:141-459 [86193]
    Other proteins in same PDB: d1nuga1, d1nuga2, d1nuga3, d1nugb1, d1nugb2, d1nugb3
    complexed with ca, cl, mg

Human (Homo sapiens), tissue isozyme [TaxId:9606] [75333] (3 PDB entries)
GDP-binding protein

Domains for 1kv3:

Domain d1kv3a4: 1kv3 A:146-468 [73030]
Other proteins in same PDB: d1kv3a1, d1kv3a2, d1kv3a3, d1kv3b1, d1kv3b2, d1kv3b3, d1kv3c1, d1kv3c2, d1kv3c3, d1kv3d1, d1kv3d2, d1kv3d3, d1kv3e1, d1kv3e2, d1kv3e3, d1kv3f1, d1kv3f2, d1kv3f3
complexed with gdp

Domain d1kv3b4: 1kv3 B:146-468 [73034]
Other proteins in same PDB: d1kv3a1, d1kv3a2, d1kv3a3, d1kv3b1, d1kv3b2, d1kv3b3, d1kv3c1, d1kv3c2, d1kv3c3, d1kv3d1, d1kv3d2, d1kv3d3, d1kv3e1, d1kv3e2, d1kv3e3, d1kv3f1, d1kv3f2, d1kv3f3
complexed with gdp

Domain d1kv3c4: 1kv3 C:146-468 [73038]
Other proteins in same PDB: d1kv3a1, d1kv3a2, d1kv3a3, d1kv3b1, d1kv3b2, d1kv3b3, d1kv3c1, d1kv3c2, d1kv3c3, d1kv3d1, d1kv3d2, d1kv3d3, d1kv3e1, d1kv3e2, d1kv3e3, d1kv3f1, d1kv3f2, d1kv3f3
complexed with gdp

Domain d1kv3d4: 1kv3 D:146-468 [73042]
Other proteins in same PDB: d1kv3a1, d1kv3a2, d1kv3a3, d1kv3b1, d1kv3b2, d1kv3b3, d1kv3c1, d1kv3c2, d1kv3c3, d1kv3d1, d1kv3d2, d1kv3d3, d1kv3e1, d1kv3e2, d1kv3e3, d1kv3f1, d1kv3f2, d1kv3f3
complexed with gdp

Domain d1kv3e4: 1kv3 E:146-468 [73046]
Other proteins in same PDB: d1kv3a1, d1kv3a2, d1kv3a3, d1kv3b1, d1kv3b2, d1kv3b3, d1kv3c1, d1kv3c2, d1kv3c3, d1kv3d1, d1kv3d2, d1kv3d3, d1kv3e1, d1kv3e2, d1kv3e3, d1kv3f1, d1kv3f2, d1kv3f3
complexed with gdp

Domain d1kv3f4: 1kv3 F:146-468 [73050]
Other proteins in same PDB: d1kv3a1, d1kv3a2, d1kv3a3, d1kv3b1, d1kv3b2, d1kv3b3, d1kv3c1, d1kv3c2, d1kv3c3, d1kv3d1, d1kv3d2, d1kv3d3, d1kv3e1, d1kv3e2, d1kv3e3, d1kv3f1, d1kv3f2, d1kv3f3
complexed with gdp

Domain for 2q3z:
- Domain d2q3za4: 2q3z A:146-461 [150040]
  Other proteins in same PDB: d2q3za1, d2q3za2, d2q3za3
  automatically matched to d1kv3a4
  complexed with so4
Domains for 3ly6:
1. Domain d3ly6a2: 3ly6 A:146-468 [247545]
  Other proteins in same PDB: d3ly6a1, d3ly6a3, d3ly6a4, d3ly6b1, d3ly6b3, d3ly6b4, d3ly6c1, d3ly6c3, d3ly6c4
  automated match to d1kv3a4
  complexed with atp
2. Domain d3ly6b2: 3ly6 B:146-468 [247549]
  Other proteins in same PDB: d3ly6a1, d3ly6a3, d3ly6a4, d3ly6b1, d3ly6b3, d3ly6b4, d3ly6c1, d3ly6c3, d3ly6c4
  automated match to d1kv3a4
  complexed with atp
3. Domain d3ly6c2: 3ly6 C:146-468 [247553]
  Other proteins in same PDB: d3ly6a1, d3ly6a3, d3ly6a4, d3ly6b1, d3ly6b3, d3ly6b4, d3ly6c1, d3ly6c3, d3ly6c4
  automated match to d1kv3a4
  complexed with atp

Red sea bream (Chrysophrys major) [TaxId:143350] [64204] (1 PDB entry)
- Domain for 1g0d:
  - Domain d1g0da4: 1g0d A:141-461 [60169]
    Other proteins in same PDB: d1g0da1, d1g0da2, d1g0da3
    complexed with so4

More info for Protein Transglutaminase catalytic domain from d.3.1.4: Transglutaminase core

Timeline for Protein Transglutaminase catalytic domain from d.3.1.4: Transglutaminase core:

Protein Transglutaminase catalytic domain from d.3.1.4: Transglutaminase core first appeared (with stable ids) in SCOP 1.55, called Protein Coagulation factor XIII, catalytic domain from d.3.1.4: Transglutaminase
Protein Transglutaminase catalytic domain from d.3.1.4: Transglutaminase core appears in SCOPe 2.03
Protein Transglutaminase catalytic domain from d.3.1.4: Transglutaminase core appears in SCOPe 2.05
Protein Transglutaminase catalytic domain from d.3.1.4: Transglutaminase core appears in the current release, SCOPe 2.08