SCOPe 2.08: Family d.3.1.4: Transglutaminase core

Lineage for Family d.3.1.4: Transglutaminase core

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.4: Transglutaminase core [54044] (3 proteins)

Proteins:

1. Peptide:N-glycanase 1, PNG1 [142852] (2 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [142853] (1 PDB entry)
      Uniprot Q02890 8-327

   2. Species Mouse (Mus musculus) [TaxId:10090] [159840] (1 PDB entry)
      Uniprot Q9JI78 164-450

2. Transglutaminase catalytic domain [54045] (4 species)

   1. Species Human (Homo sapiens), blood isozyme [TaxId:9606] [54046] (9 PDB entries)
      Coagulation factor XIII

   2. Species Human (Homo sapiens), TGase E3 [TaxId:9606] [75334] (9 PDB entries)

   3. Species Human (Homo sapiens), tissue isozyme [TaxId:9606] [75333] (5 PDB entries)
      GDP-binding protein

   4. Species Red sea bream (Chrysophrys major) [TaxId:143350] [64204] (1 PDB entry)

3. automated matches [190634] (3 species)
   not a true protein

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [188107] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [256347] (1 PDB entry)

   3. Species Mouse (Mus musculus) [TaxId:10090] [187686] (1 PDB entry)

More info for Family d.3.1.4: Transglutaminase core

Timeline for Family d.3.1.4: Transglutaminase core:

• Family d.3.1.4: Transglutaminase core first appeared (with stable ids) in SCOP 1.55, called Family d.3.1.4: Transglutaminase
  
• Family d.3.1.4: Transglutaminase core appears in SCOPe 2.07