SCOPe 2.07: Protein: Calpain large subunit, catalytic domain (domain II)

Lineage for Protein: Calpain large subunit, catalytic domain (domain II)

Root: SCOPe 2.07
Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
Fold d.3: Cysteine proteinases [54000] (1 superfamily)
consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

Superfamily d.3.1: Cysteine proteinases [54001] (24 families)

the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

Family d.3.1.3: Calpain large subunit, catalytic domain (domain II) [54040] (1 protein)
automatically mapped to Pfam PF00648
Protein Calpain large subunit, catalytic domain (domain II) [54041] (6 species)
includes the N-terminal 'sequence' domain I

Species:

Human (Homo sapiens) [TaxId:9606] [225239] (1 PDB entry)
- Domains for 2p0r:
  1. Domain d2p0ra_: 2p0r A: [205405]
    automated match to d1mdwa_
    complexed with ca
  2. Domain d2p0rb_: 2p0r B: [205406]
    automated match to d1mdwa_
    complexed with ca
Human (Homo sapiens), calpain 9 [TaxId:9606] [142850] (1 PDB entry)
Uniprot O14815 28-337
- Domain for 1ziv:
  - Domain d1ziva1: 1ziv A:28-337 [125139]
    complexed with bme, ca
Human (Homo sapiens), M-type [TaxId:9606] [54042] (2 PDB entries)
1. Domain for 1kfu:
  - Domain d1kful3: 1kfu L:2-355 [68573]
    Other proteins in same PDB: d1kful1, d1kful2, d1kfus_
2. Domain for 1kfx:
  - Domain d1kfxl3: 1kfx L:2-355 [68577]
    Other proteins in same PDB: d1kfxl1, d1kfxl2, d1kfxs_
Human (Homo sapiens), mu type [TaxId:9606] [142851] (2 PDB entries)
Uniprot P07384 33-353! Uniprot P07384 33-354
1. Domain for 1zcm:
  - Domain d1zcma1: 1zcm A:33-353 [124909]
    complexed with c1n, ca
2. Domains for 2ary:
  1. Domain d2arya1: 2ary A:33-354 [127223]
    complexed with bme, ca
  2. Domain d2aryb_: 2ary B: [127224]
    automated match to d2arya1
    complexed with bme, ca
Norway rat (Rattus norvegicus), M-type [TaxId:10116] [54043] (3 PDB entries)
1. Domain for 1df0:
  - Domain d1df0a3: 1df0 A:2-355 [37106]
    Other proteins in same PDB: d1df0a1, d1df0a2, d1df0b_
2. Domains for 1mdw:
  1. Domain d1mdwa_: 1mdw A: [84934]
    calcium-bound protease core
    complexed with ca
  2. Domain d1mdwb_: 1mdw B: [84935]
    calcium-bound protease core
    complexed with ca
3. Domain for 1u5i:
  - Domain d1u5ia3: 1u5i A:2-355 [119549]
    Other proteins in same PDB: d1u5ia1, d1u5ia2, d1u5ib_
    automatically matched to d1df0a3
    mutant
Norway rat (Rattus norvegicus), mu-type [TaxId:10116] [75332] (10 PDB entries)
Uniprot P97571 33-353
1. Domains for 1kxr:
  1. Domain d1kxra_: 1kxr A: [73175]
    calcium-bound protease core
    complexed with ca
  2. Domain d1kxrb_: 1kxr B: [73176]
    calcium-bound protease core
    complexed with ca
2. Domains for 1qxp:
  1. Domain d1qxpa4: 1qxp A:2-355 [96546]
    Other proteins in same PDB: d1qxpa1, d1qxpa2, d1qxpa3, d1qxpb1, d1qxpb2, d1qxpb3
    mu-like isoform with the large and small subunits fused in a single chain
  2. Domain d1qxpb4: 1qxp B:2-355 [96550]
    Other proteins in same PDB: d1qxpa1, d1qxpa2, d1qxpa3, d1qxpb1, d1qxpb2, d1qxpb3
    mu-like isoform with the large and small subunits fused in a single chain
3. Domain for 1tl9:
  - Domain d1tl9a_: 1tl9 A: [112505]
    complexed with ca
4. Domain for 1tlo:
  - Domain d1tloa_: 1tlo A: [112508]
    complexed with ca, e64
5. Domain for 2g8e:
  - Domain d2g8ea2: 2g8e A:33-356 [134769]
    Other proteins in same PDB: d2g8ea3
    automated match to d1tloa_
    complexed with 0m6, ca, mes
6. Domain for 2g8j:
  - Domain d2g8ja_: 2g8j A: [134773]
    automated match to d1tloa_
    complexed with ca, d7g
7. Domain for 2nqg:
  - Domain d2nqga_: 2nqg A: [138453]
    automated match to d1tloa_
    complexed with ca, nqg
8. Domain for 2nqi:
  - Domain d2nqia_: 2nqi A: [138454]
    automated match to d1tloa_
    complexed with ca, nqi
9. Domain for 2r9c:
  - Domain d2r9ca_: 2r9c A: [151766]
    automated match to d1tloa_
    complexed with ca, cl, gol, grd
10. Domain for 2r9f:
  - Domain d2r9fa_: 2r9f A: [151767]
    automated match to d1tloa_
    complexed with ca, cl, gol, k2z

More info for Protein Calpain large subunit, catalytic domain (domain II) from d.3.1.3: Calpain large subunit, catalytic domain (domain II)

Timeline for Protein Calpain large subunit, catalytic domain (domain II) from d.3.1.3: Calpain large subunit, catalytic domain (domain II):

Protein Calpain large subunit, catalytic domain (domain II) from d.3.1.3: Calpain large subunit, catalytic domain (domain II) first appeared (with stable ids) in SCOP 1.55
Protein Calpain large subunit, catalytic domain (domain II) from d.3.1.3: Calpain large subunit, catalytic domain (domain II) appears in SCOPe 2.06
Protein Calpain large subunit, catalytic domain (domain II) from d.3.1.3: Calpain large subunit, catalytic domain (domain II) appears in the current release, SCOPe 2.08