SCOP 1.75: Protein: Calpain large subunit, catalytic domain (domain II)

Lineage for Protein: Calpain large subunit, catalytic domain (domain II)

Root: SCOP 1.75
Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
Fold d.3: Cysteine proteinases [54000] (1 superfamily)
consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

Superfamily d.3.1: Cysteine proteinases [54001] (22 families)

the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

Family d.3.1.3: Calpain large subunit, catalytic domain (domain II) [54040] (1 protein)
Protein Calpain large subunit, catalytic domain (domain II) [54041] (5 species)
includes the N-terminal 'sequence' domain I

Species:

Human (Homo sapiens), calpain 9 [TaxId:9606] [142850] (1 PDB entry)
Uniprot O14815 28-337
- Domain for 1ziv:
  - Domain d1ziva1: 1ziv A:28-337 [125139]
    complexed with bme, ca
Human (Homo sapiens), M-type [TaxId:9606] [54042] (2 PDB entries)
1. Domain for 1kfu:
  - Domain d1kful3: 1kfu L:2-355 [68573]
    Other proteins in same PDB: d1kful1, d1kful2, d1kfus_
2. Domain for 1kfx:
  - Domain d1kfxl3: 1kfx L:2-355 [68577]
    Other proteins in same PDB: d1kfxl1, d1kfxl2, d1kfxs_
Human(Homo sapiens), mu type [TaxId:9606] [142851] (2 PDB entries)
Uniprot P07384 33-353! Uniprot P07384 33-354
1. Domain for 1zcm:
  - Domain d1zcma1: 1zcm A:33-353 [124909]
    complexed with c1n, ca; mutant
2. Domains for 2ary:
  1. Domain d2arya1: 2ary A:33-354 [127223]
    complexed with bme, ca
  2. Domain d2aryb1: 2ary B:33-354 [127224]
    automatically matched to 2ARY A:33-354
    complexed with bme, ca
Rat (Rattus norvegicus), M-type [TaxId:10116] [54043] (3 PDB entries)
1. Domain for 1df0:
  - Domain d1df0a3: 1df0 A:2-355 [37106]
    Other proteins in same PDB: d1df0a1, d1df0a2, d1df0b_
    mutant
2. Domains for 1mdw:
  1. Domain d1mdwa_: 1mdw A: [84934]
    calcium-bound protease core
  2. Domain d1mdwb_: 1mdw B: [84935]
    calcium-bound protease core
    complexed with ca; mutant
3. Domain for 1u5i:
  - Domain d1u5ia3: 1u5i A:2-355 [119549]
    Other proteins in same PDB: d1u5ia1, d1u5ia2, d1u5ib1
    automatically matched to d1df0a3
    mutant
Rat (Rattus norvegicus), mu-type [TaxId:10116] [75332] (10 PDB entries)
Uniprot P97571 33-353
1. Domains for 1kxr:
  1. Domain d1kxra_: 1kxr A: [73175]
    calcium-bound protease core
  2. Domain d1kxrb_: 1kxr B: [73176]
    calcium-bound protease core
    complexed with ca; mutant
2. Domains for 1qxp:
  1. Domain d1qxpa4: 1qxp A:2-355 [96546]
    Other proteins in same PDB: d1qxpa1, d1qxpa2, d1qxpa3, d1qxpb1, d1qxpb2, d1qxpb3
    mu-like isoform with the large and small subunits fused in a single chain
  2. Domain d1qxpb4: 1qxp B:2-355 [96550]
    Other proteins in same PDB: d1qxpa1, d1qxpa2, d1qxpa3, d1qxpb1, d1qxpb2, d1qxpb3
    mu-like isoform with the large and small subunits fused in a single chain
    mutant
3. Domain for 1tl9:
  - Domain d1tl9a_: 1tl9 A: [112505]
    complexed with ace, ca
4. Domain for 1tlo:
  - Domain d1tloa_: 1tlo A: [112508]
    complexed with ca, e64
5. Domain for 2g8e:
  - Domain d2g8ea1: 2g8e A:33-354 [134769]
    automatically matched to d1tloa_
    complexed with ca, d5g, mes
6. Domain for 2g8j:
  - Domain d2g8ja1: 2g8j A:33-354 [134773]
    automatically matched to d1tloa_
    complexed with ca, d7g
7. Domain for 2nqg:
  - Domain d2nqga1: 2nqg A:33-354 [138453]
    automatically matched to d1tloa_
    complexed with ca, nqg
8. Domain for 2nqi:
  - Domain d2nqia1: 2nqi A:33-354 [138454]
    automatically matched to d1tloa_
    complexed with ca, nqi
9. Domain for 2r9c:
  - Domain d2r9ca1: 2r9c A:33-354 [151766]
    automatically matched to d1tloa_
    complexed with ca, cl, gol, grd
10. Domain for 2r9f:
  - Domain d2r9fa1: 2r9f A:33-354 [151767]
    automatically matched to d1tloa_
    complexed with ca, cl, gol, k2z

More info for Protein Calpain large subunit, catalytic domain (domain II) from d.3.1.3: Calpain large subunit, catalytic domain (domain II)

Timeline for Protein Calpain large subunit, catalytic domain (domain II) from d.3.1.3: Calpain large subunit, catalytic domain (domain II):

Protein Calpain large subunit, catalytic domain (domain II) from d.3.1.3: Calpain large subunit, catalytic domain (domain II) first appeared (with stable ids) in SCOP 1.55
Protein Calpain large subunit, catalytic domain (domain II) from d.3.1.3: Calpain large subunit, catalytic domain (domain II) appears in SCOP 1.73
Protein Calpain large subunit, catalytic domain (domain II) from d.3.1.3: Calpain large subunit, catalytic domain (domain II) appears in SCOPe 2.01
Protein Calpain large subunit, catalytic domain (domain II) from d.3.1.3: Calpain large subunit, catalytic domain (domain II) appears in the current release, SCOPe 2.08