SCOP 1.75: Family c.95.1.2: Chalcone synthase-like

Lineage for Family c.95.1.2: Chalcone synthase-like

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.95: Thiolase-like [53900] (1 superfamily)
   consists of two similar domains related by pseudo dyad; duplication
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32451; strand 5 is antiparallel to the rest

4. Superfamily c.95.1: Thiolase-like [53901] (2 families)

5. Family c.95.1.2: Chalcone synthase-like [53914] (8 proteins)

Proteins:

1. 3-hydroxy-3-methylglutaryl CoA synthase MvaS [110760] (1 species)
   most similar to FabH

   • Species Staphylococcus aureus [TaxId:1280] [110761] (5 PDB entries)
     Uniprot Q7A3F6

2. Chalcone synthase [53915] (1 species)

   • Species Alfalfa (Medicago sativa) [TaxId:3879] [53916] (16 PDB entries)
     Uniprot P30074

3. Dihydropinosylvin synthase [117752] (1 species)

   • Species Scots pine (Pinus sylvestris) [TaxId:3349] [117753] (1 PDB entry)
     Uniprot Q02323

4. Ketoacyl-ACP synthase III (FabH) [53912] (3 species)

   1. Species Escherichia coli [TaxId:562] [53913] (9 PDB entries)

   2. Species Mycobacterium tuberculosis [TaxId:1773] [64196] (12 PDB entries)

   3. Species Thermus thermophilus [TaxId:274] [89794] (1 PDB entry)

5. Polyketide synthase PKS18 [110758] (1 species)

   • Species Mycobacterium tuberculosis [TaxId:1773] [110759] (2 PDB entries)
     Uniprot Q79FQ0

6. Priming beta-ketosynthase from the r1128 polyketide biosynthetic pathway [82561] (1 species)

   • Species Streptomyces sp. r1128 [TaxId:140437] [82562] (1 PDB entry)

7. Putative polyketide synthase SCO1206 [110762] (1 species)

   • Species Streptomyces coelicolor [TaxId:1902] [110763] (1 PDB entry)
     Uniprot Q9FCA7

8. Pyrone synthase (PyS, chalcone synthase 2) [53917] (1 species)

   • Species Gerbera hybrid cultivar [TaxId:18101] [53918] (2 PDB entries)

More info for Family c.95.1.2: Chalcone synthase-like

Timeline for Family c.95.1.2: Chalcone synthase-like:

• Family c.95.1.2: Chalcone synthase-like first appeared (with stable ids) in SCOP 1.55, called Family c.95.1.2: Chalcone synthase
  
• Family c.95.1.2: Chalcone synthase-like appears in SCOP 1.73
  
• Family c.95.1.2: Chalcone synthase-like appears in SCOPe 2.01
  
• Family c.95.1.2: Chalcone synthase-like appears in the current release, SCOPe 2.08