Lineage for Protein: Ketoacyl-ACP synthase III (FabH)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2916469Fold c.95: Thiolase-like [53900] (1 superfamily)
    consists of two similar domains related by pseudo dyad; duplication
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32451; strand 5 is antiparallel to the rest
  4. 2916470Superfamily c.95.1: Thiolase-like [53901] (3 families) (S)
  5. 2916987Family c.95.1.2: Chalcone synthase-like [53914] (15 proteins)
  6. 2917122Protein Ketoacyl-ACP synthase III (FabH) [53912] (5 species)

Species:

  1. 2917123Escherichia coli [TaxId:316385] [407256] (1 PDB entry)
  2. 2917126Escherichia coli [TaxId:562] [53913] (14 PDB entries)
    1. Domains for 1d9b:
      1. 2917139Domain d1d9ba1: 1d9b A:1-174 [302305]
        automated match to d1hnja1
      2. 2917140Domain d1d9ba2: 1d9b A:175-317 [302306]
        automated match to d1hnja2
      3. 2917141Domain d1d9bb1: 1d9b B:1-174 [302307]
        automated match to d1hnja1
      4. 2917142Domain d1d9bb2: 1d9b B:175-317 [302308]
        automated match to d1hnja2
    2. Domains for 1ebl:
      1. 2917157Domain d1ebla1: 1ebl A:1-174 [35973]
        complexed with coa
      2. 2917158Domain d1ebla2: 1ebl A:175-317 [35974]
        complexed with coa
      3. 2917159Domain d1eblb1: 1ebl B:1-174 [35975]
        complexed with coa
      4. 2917160Domain d1eblb2: 1ebl B:175-317 [35976]
        complexed with coa
    3. Domains for 1hn9:
      1. 2917133Domain d1hn9a1: 1hn9 A:1-174 [35977]
        complexed with po4
      2. 2917134Domain d1hn9a2: 1hn9 A:175-317 [35978]
        complexed with po4
      3. 2917135Domain d1hn9b1: 1hn9 B:1001-1174 [35979]
        complexed with po4
      4. 2917136Domain d1hn9b2: 1hn9 B:1175-1317 [35980]
        complexed with po4
    4. Domains for 1hnd:
      1. 2917131Domain d1hnda1: 1hnd A:1-174 [35971]
        complexed with coa
      2. 2917132Domain d1hnda2: 1hnd A:175-317 [35972]
        complexed with coa
    5. Domains for 1hnh:
      1. 2917147Domain d1hnha1: 1hnh A:1-174 [35983]
        complexed with coa
      2. 2917148Domain d1hnha2: 1hnh A:175-317 [35984]
        complexed with coa
    6. Domains for 1hnj:
      1. 2917127Domain d1hnja1: 1hnj A:1-174 [35969]
        complexed with mlc, po4
      2. 2917128Domain d1hnja2: 1hnj A:175-317 [35970]
        complexed with mlc, po4
    7. Domains for 1hnk:
      1. 2917137Domain d1hnka1: 1hnk A:1-174 [35981]
      2. 2917138Domain d1hnka2: 1hnk A:175-317 [35982]
    8. Domains for 1mzs:
      1. 2917163Domain d1mzsa1: 1mzs A:1-174 [79711]
        complexed with 669, po4
      2. 2917164Domain d1mzsa2: 1mzs A:175-317 [79712]
        complexed with 669, po4
    9. Domains for 2eft:
      1. 2917143Domain d2efta1: 2eft A:1-174 [132105]
        automated match to d1hnja1
        complexed with coa, mee, so4
      2. 2917144Domain d2efta2: 2eft A:175-317 [132106]
        automated match to d1hnja2
        complexed with coa, mee, so4
      3. 2917145Domain d2eftb1: 2eft B:1-174 [132107]
        automated match to d1hnja1
        complexed with coa, mee, so4
      4. 2917146Domain d2eftb2: 2eft B:175-317 [132108]
        automated match to d1hnja2
        complexed with coa, mee, so4
    10. Domains for 2gyo:
      1. 2917149Domain d2gyoa1: 2gyo A:1-174 [135859]
        automated match to d1hnja1
        complexed with coa, mee, so4
      2. 2917150Domain d2gyoa2: 2gyo A:175-317 [135860]
        automated match to d1hnja2
        complexed with coa, mee, so4
      3. 2917151Domain d2gyob1: 2gyo B:1-174 [135861]
        automated match to d1hnja1
        complexed with coa, mee, so4
      4. 2917152Domain d2gyob2: 2gyo B:175-317 [135862]
        automated match to d1hnja2
        complexed with coa, mee, so4
    11. Domains for 5bnm:
      1. 2917153Domain d5bnma1: 5bnm A:1-174 [317392]
        automated match to d1hnja1
        complexed with 4vk, pg4, so4
      2. 2917154Domain d5bnma2: 5bnm A:175-317 [317393]
        automated match to d1hnja2
        complexed with 4vk, pg4, so4
      3. 2917155Domain d5bnmb1: 5bnm B:1-174 [317391]
        automated match to d1hnja1
        complexed with 4vk, pg4, so4
      4. 2917156Domain d5bnmb2: 5bnm B:175-317 [317394]
        automated match to d1hnja2
        complexed with 4vk, pg4, so4
    12. Domains for 5bnr:
      1. 2917161Domain d5bnra1: 5bnr A:1-174 [317475]
        automated match to d1hnja1
        complexed with 4vl
      2. 2917162Domain d5bnra2: 5bnr A:175-317 [317476]
        automated match to d1hnja2
        complexed with 4vl
    13. Domains for 5bns:
      1. 2917165Domain d5bnsa1: 5bns A:1-174 [317454]
        automated match to d1hnja1
        complexed with 4vm
      2. 2917166Domain d5bnsa2: 5bns A:175-317 [317455]
        automated match to d1hnja2
        complexed with 4vm
      3. 2917167Domain d5bnsb1: 5bns B:1-174 [317418]
        automated match to d1hnja1
        complexed with 4vm
      4. 2917168Domain d5bnsb2: 5bns B:175-317 [317419]
        automated match to d1hnja2
        complexed with 4vm
    14. Domains for 6x7s:
      1. 2917129Domain d6x7sa1: 6x7s A:1-174 [407360]
        Other proteins in same PDB: d6x7sa3
        automated match to d1hnja1
        complexed with dms, mg, ut7
      2. 2917130Domain d6x7sa2: 6x7s A:175-317 [407361]
        Other proteins in same PDB: d6x7sa3
        automated match to d1ebla2
        complexed with dms, mg, ut7
  3. 2917169Escherichia coli [TaxId:83334] [317080] (1 PDB entry)
  4. 2917174Mycobacterium tuberculosis [TaxId:1773] [64196] (12 PDB entries)
    1. Domains for 1hzp:
      1. 2917191Domain d1hzpa1: 1hzp A:-10-174 [61455]
        complexed with dao, gol
      2. 2917192Domain d1hzpa2: 1hzp A:175-317 [61456]
        complexed with dao, gol
      3. 2917193Domain d1hzpb1: 1hzp B:-10-174 [61457]
        complexed with dao, gol
      4. 2917194Domain d1hzpb2: 1hzp B:175-317 [61458]
        complexed with dao, gol
    2. Domains for 1m1m:
      1. 2917199Domain d1m1ma1: 1m1m A:2-185 [74409]
      2. 2917200Domain d1m1ma2: 1m1m A:186-333 [74410]
      3. 2917201Domain d1m1mb1: 1m1m B:5-185 [74411]
      4. 2917202Domain d1m1mb2: 1m1m B:186-333 [74412]
    3. Domains for 1u6e:
      1. 2917175Domain d1u6ea1: 1u6e A:-10-174 [119568]
        automated match to d2qnza1
        complexed with cl; mutant
      2. 2917176Domain d1u6ea2: 1u6e A:175-317B [119569]
        automated match to d1u6ea2
        complexed with cl; mutant
      3. 2917177Domain d1u6eb1: 1u6e B:-10-174 [119570]
        automated match to d2qnza1
        complexed with cl; mutant
      4. 2917178Domain d1u6eb2: 1u6e B:175-317B [119571]
        automated match to d1u6eb2
        complexed with cl; mutant
    4. Domains for 1u6s:
      1. 2917203Domain d1u6sa1: 1u6s A:-10-174 [119604]
        automated match to d2qnza1
        complexed with dcc
      2. 2917204Domain d1u6sa2: 1u6s A:175-317B [119605]
        automated match to d2ahba2
        complexed with dcc
      3. 2917205Domain d1u6sb1: 1u6s B:-10-174 [119606]
        automated match to d2qnza1
        complexed with dcc
      4. 2917206Domain d1u6sb2: 1u6s B:175-317B [119607]
        automated match to d2ahba2
        complexed with dcc
    5. Domains for 2ahb:
      1. 2917187Domain d2ahba1: 2ahb A:1-184 [126744]
        automated match to d2qnza1
        mutant
      2. 2917188Domain d2ahba2: 2ahb A:185-334 [126745]
        automated match to d2ahba2
        mutant
      3. 2917189Domain d2ahbb1: 2ahb B:1-184 [126746]
        automated match to d2qnza1
        mutant
      4. 2917190Domain d2ahbb2: 2ahb B:185-334 [126747]
        automated match to d2ahbb2
        mutant
    6. Domains for 2aj9:
      1. 2917207Domain d2aj9a1: 2aj9 A:1-184 [126852]
        automated match to d2qnza1
        mutant
      2. 2917208Domain d2aj9a2: 2aj9 A:185-334 [126853]
        automated match to d1hzpa2
        mutant
      3. 2917209Domain d2aj9b1: 2aj9 B:1-184 [126854]
        automated match to d2qnza1
        mutant
      4. 2917210Domain d2aj9b2: 2aj9 B:185-334 [126855]
        automated match to d1hzpa2
        mutant
    7. Domains for 2qnx:
      1. 2917219Domain d2qnxa1: 2qnx A:-10-174 [150956]
        automated match to d1hzpa1
        complexed with mdx, udt
      2. 2917220Domain d2qnxa2: 2qnx A:175-317B [150957]
        automated match to d1hzpa2
        complexed with mdx, udt
      3. 2917221Domain d2qnxb1: 2qnx B:-10-174 [150958]
        automated match to d1hzpa1
        complexed with mdx, udt
      4. 2917222Domain d2qnxb2: 2qnx B:175-317B [150959]
        automated match to d1hzpa2
        complexed with mdx, udt
    8. Domains for 2qny:
      1. 2917195Domain d2qnya1: 2qny A:-9-174 [150960]
        automated match to d2qnza1
        complexed with bme, dfd; mutant
      2. 2917196Domain d2qnya2: 2qny A:175-317B [150961]
        automated match to d1hzpa2
        complexed with bme, dfd; mutant
      3. 2917197Domain d2qnyb1: 2qny B:-10-174 [150962]
        automated match to d2qnza1
        complexed with bme, dfd; mutant
      4. 2917198Domain d2qnyb2: 2qny B:175-317B [150963]
        automated match to d1hzpa2
        complexed with bme, dfd; mutant
    9. Domains for 2qnz:
      1. 2917179Domain d2qnza1: 2qnz A:-10-174 [150964]
        automated match to d1hzpa1
        complexed with bme, dfd
      2. 2917180Domain d2qnza2: 2qnz A:175-317B [150965]
        automated match to d1hzpa2
        complexed with bme, dfd
      3. 2917181Domain d2qnzb1: 2qnz B:-10-174 [150966]
        automated match to d1hzpa1
        complexed with bme, dfd
      4. 2917182Domain d2qnzb2: 2qnz B:175-317B [150967]
        automated match to d1hzpa2
        complexed with bme, dfd
    10. Domains for 2qo0:
      1. 2917183Domain d2qo0a1: 2qo0 A:-10-174 [150968]
        automated match to d2qnza1
        complexed with d1t; mutant
      2. 2917184Domain d2qo0a2: 2qo0 A:175-317B [150969]
        automated match to d1hzpa2
        complexed with d1t; mutant
      3. 2917185Domain d2qo0b1: 2qo0 B:-10-174 [150970]
        automated match to d2qnza1
        complexed with d1t; mutant
      4. 2917186Domain d2qo0b2: 2qo0 B:175-317B [150971]
        automated match to d1hzpa2
        complexed with d1t; mutant
    11. Domains for 2qo1:
      1. 2917211Domain d2qo1a1: 2qo1 A:-10-174 [150972]
        automated match to d1hzpa1
        complexed with d1t, vzz
      2. 2917212Domain d2qo1a2: 2qo1 A:175-317B [150973]
        automated match to d1hzpa2
        complexed with d1t, vzz
      3. 2917213Domain d2qo1b1: 2qo1 B:-10-174 [150974]
        automated match to d1hzpa1
        complexed with d1t, vzz
      4. 2917214Domain d2qo1b2: 2qo1 B:175-317B [150975]
        automated match to d1hzpa2
        complexed with d1t, vzz
    12. Domains for 2qx1:
      1. 2917215Domain d2qx1a1: 2qx1 A:-10-174 [151443]
        automated match to d1hzpa1
        complexed with coa, d1t
      2. 2917216Domain d2qx1a2: 2qx1 A:175-317B [151444]
        automated match to d1hzpa2
        complexed with coa, d1t
      3. 2917217Domain d2qx1b1: 2qx1 B:-10-174 [151445]
        automated match to d1hzpa1
        complexed with coa, d1t
      4. 2917218Domain d2qx1b2: 2qx1 B:175-317B [151446]
        automated match to d1hzpa2
        complexed with coa, d1t
  5. 2917223Thermus thermophilus [TaxId:274] [89794] (1 PDB entry)

More info for Protein Ketoacyl-ACP synthase III (FabH) from c.95.1.2: Chalcone synthase-like

Timeline for Protein Ketoacyl-ACP synthase III (FabH) from c.95.1.2: Chalcone synthase-like: