SCOPe 2.06: Family c.95.1.1: Thiolase-related

Lineage for Family c.95.1.1: Thiolase-related

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.95: Thiolase-like [53900] (1 superfamily)
   consists of two similar domains related by pseudo dyad; duplication
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32451; strand 5 is antiparallel to the rest

4. Superfamily c.95.1: Thiolase-like [53901] (3 families)

5. Family c.95.1.1: Thiolase-related [53902] (10 proteins)

Proteins:

1. Actinorhodin polyketide putative beta-ketoacyl synthase 1, KasA [110752] (1 species)

   • Species Streptomyces coelicolor [TaxId:1902] [110753] (1 PDB entry)
     Uniprot Q02059

2. Actinorhodin polyketide putative beta-ketoacyl synthase 2, KasB [110754] (1 species)

   • Species Streptomyces coelicolor [TaxId:1902] [110755] (1 PDB entry)
     Uniprot Q02062

3. Beta-ketoacyl-ACP synthase I [53907] (1 species)

   • Species Escherichia coli [TaxId:562] [53908] (19 PDB entries)
     Uniprot P14926

4. Beta-ketoacyl-ACP synthase II [53909] (6 species)

   1. Species Escherichia coli [TaxId:562] [53910] (4 PDB entries)

   2. Species Pneumococcus (Streptococcus pneumoniae) [TaxId:1313] [89793] (4 PDB entries)

   3. Species Staphylococcus aureus [TaxId:1280] [225072] (1 PDB entry)

   4. Species Synechocystis sp. [TaxId:1143] [53911] (1 PDB entry)

   5. Species Thale cress (Arabidopsis thaliana), mitochondrial isoform [TaxId:3702] [117749] (2 PDB entries)
      Uniprot Q8L3X9

   6. Species Thermus thermophilus [TaxId:274] [89792] (1 PDB entry)

5. Beta-ketoadipyl CoA thiolase [117750] (1 species)

   • Species Thermus thermophilus [TaxId:274] [117751] (1 PDB entry)
     Uniprot Q5SJM1

6. Biosynthetic thiolase [53905] (1 species)

   • Species Zoogloea ramigera [TaxId:350] [53906] (16 PDB entries)
     Uniprot P07097

7. Fatty oxidation complex beta subunit (3-ketoacyl-CoA thiolase) [110756] (1 species)

   • Species Pseudomonas fragi [TaxId:296] [110757] (4 PDB entries)
     Uniprot P28790

8. Ketosynthase domain from 6-deoxyerythronolide B synthase (DEBS) [310768] (1 species)

   • Species Saccharopolyspora erythraea [TaxId:1836] [311024] (1 PDB entry)

9. Thiolase [53903] (1 species)
   topology of each domain is similar to the first domain of phosphoglucomutase

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [53904] (2 PDB entries)

10. automated matches [231410] (2 species)
    not a true protein

    1. Species Escherichia coli [TaxId:562] [254877] (8 PDB entries)

    2. Species Zoogloea ramigera [TaxId:350] [231411] (6 PDB entries)

More info for Family c.95.1.1: Thiolase-related

Timeline for Family c.95.1.1: Thiolase-related:

• Family c.95.1.1: Thiolase-related first appeared (with stable ids) in SCOP 1.55
  
• Family c.95.1.1: Thiolase-related appears in SCOPe 2.05
  
• Family c.95.1.1: Thiolase-related appears in SCOPe 2.07
  
• Family c.95.1.1: Thiolase-related appears in the current release, SCOPe 2.08