SCOP 1.71: Family c.95.1.1: Thiolase-related

Lineage for Family c.95.1.1: Thiolase-related

1. Root: SCOP 1.71

2. Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

3. Fold c.95: Thiolase-like [53900] (1 superfamily)
   consists of two similar domains related by pseudo dyad; duplication
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32451; strand 5 is antiparallel to the rest

4. Superfamily c.95.1: Thiolase-like [53901] (2 families)

5. Family c.95.1.1: Thiolase-related [53902] (8 proteins)

Proteins:

1. Actinorhodin polyketide putative beta-ketoacyl synthase 1, KasA [110752] (1 species)

   • Species Streptomyces coelicolor [TaxId:1902] [110753] (1 PDB entry)

2. Actinorhodin polyketide putative beta-ketoacyl synthase 2, KasB [110754] (1 species)

   • Species Streptomyces coelicolor [TaxId:1902] [110755] (1 PDB entry)

3. Beta-ketoacyl-ACP synthase I [53907] (1 species)

   • Species Escherichia coli [TaxId:562] [53908] (11 PDB entries)

4. Beta-ketoacyl-ACP synthase II [53909] (5 species)

   1. Species Escherichia coli [TaxId:562] [53910] (2 PDB entries)

   2. Species Streptococcus pneumoniae [TaxId:1313] [89793] (2 PDB entries)

   3. Species Synechocystis sp. [TaxId:1143] [53911] (1 PDB entry)

   4. Species Thale cress (Arabidopsis thaliana), mitochondrial isoform [TaxId:3702] [117749] (1 PDB entry)

   5. Species Thermus thermophilus [TaxId:274] [89792] (1 PDB entry)

5. Beta-ketoadipyl CoA thiolase [117750] (1 species)

   • Species Thermus thermophilus [TaxId:274] [117751] (1 PDB entry)

6. Biosynthetic thiolase [53905] (1 species)

   • Species Zoogloea ramigera [TaxId:350] [53906] (12 PDB entries)

7. Fatty oxidation complex beta subunit (3-ketoacyl-CoA thiolase) [110756] (1 species)

   • Species Pseudomonas fragi [TaxId:296] [110757] (3 PDB entries)

8. Thiolase [53903] (1 species)
   topology of each domain is similar to the first domain of phosphoglucomutase

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [53904] (2 PDB entries)

More info for Family c.95.1.1: Thiolase-related

Timeline for Family c.95.1.1: Thiolase-related:

• Family c.95.1.1: Thiolase-related first appeared (with stable ids) in SCOP 1.55
  
• Family c.95.1.1: Thiolase-related appears in SCOP 1.69
  
• Family c.95.1.1: Thiolase-related appears in SCOP 1.73
  
• Family c.95.1.1: Thiolase-related appears in the current release, SCOPe 2.08