SCOP 1.67: Family c.95.1.1: Thiolase-related

Lineage for Family c.95.1.1: Thiolase-related

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.95: Thiolase-like [53900] (1 superfamily)
   consists of two similar domains related by pseudo dyad; duplication
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32451; strand 5 is antiparallel to the rest

4. Superfamily c.95.1: Thiolase-like [53901] (2 families)

5. Family c.95.1.1: Thiolase-related [53902] (6 proteins)

Proteins:

1. Beta-ketoacyl-ACP synthase I [53907] (1 species)

   • Species Escherichia coli [TaxId:562] [53908] (9 PDB entries)

2. Beta-ketoacyl-ACP synthase II [53909] (4 species)

   1. Species Escherichia coli [TaxId:562] [53910] (2 PDB entries)

   2. Species Streptococcus pneumoniae [TaxId:1313] [89793] (2 PDB entries)

   3. Species Synechocystis sp. [TaxId:1143] [53911] (1 PDB entry)

   4. Species Thermus thermophilus [TaxId:274] [89792] (1 PDB entry)

3. Biosynthetic thiolase [53905] (1 species)

   • Species Zoogloea ramigera [TaxId:350] [53906] (11 PDB entries)

4. Ketoacyl-ACP synthase III (FabH) [53912] (3 species)

   1. Species Escherichia coli [TaxId:562] [53913] (7 PDB entries)

   2. Species Mycobacterium tuberculosis [TaxId:1773] [64196] (2 PDB entries)

   3. Species Thermus thermophilus [TaxId:274] [89794] (1 PDB entry)

5. Priming beta-ketosynthase from the r1128 polyketide biosynthetic pathway [82561] (1 species)

   • Species Streptomyces sp. r1128 [TaxId:140437] [82562] (1 PDB entry)

6. Thiolase [53903] (1 species)
   topology of each domain is similar to the first domain of phosphoglucomutase

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [53904] (2 PDB entries)

More info for Family c.95.1.1: Thiolase-related

Timeline for Family c.95.1.1: Thiolase-related:

• Family c.95.1.1: Thiolase-related first appeared (with stable ids) in SCOP 1.55
  
• Family c.95.1.1: Thiolase-related appears in SCOP 1.65
  
• Family c.95.1.1: Thiolase-related appears in SCOP 1.69
  
• Family c.95.1.1: Thiolase-related appears in the current release, SCOPe 2.08