Lineage for Protein: Lactoferrin

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 710610Fold c.94: Periplasmic binding protein-like II [53849] (1 superfamily)
    consists of two similar intertwined domain with 3 layers (a/b/a) each: duplication
    mixed beta-sheet of 5 strands, order 21354; strand 5 is antiparallel to the rest
  4. 710611Superfamily c.94.1: Periplasmic binding protein-like II [53850] (2 families) (S)
    Similar in architecture to the superfamily I but partly differs in topology
  5. 711143Family c.94.1.2: Transferrin [53888] (3 proteins)
    further duplication: composed of two two-domain lobes
  6. 711144Protein Lactoferrin [53889] (6 species)

Species:

  1. 711145Arabian camel (Camelus dromedarius) [TaxId:9838] [64195] (2 PDB entries)
    1. Domains for 1dtz:
      1. 711146Domain d1dtza1: 1dtz A:1-333 [59134]
      2. 711147Domain d1dtza2: 1dtz A:334-689 [59135]
    2. Domains for 1i6q:
      1. 711148Domain d1i6qa1: 1i6q A:1-333 [66043]
      2. 711149Domain d1i6qa2: 1i6q A:334-689 [66044]
        complexed with co3, fe
  2. 711150Cow (Bos taurus) [TaxId:9913] [53891] (36 PDB entries)
    1. Domains for 1blf:
      1. 711186Domain d1blfa1: 1blf A:5-333 [35859]
      2. 711187Domain d1blfa2: 1blf A:334-689 [35860]
        complexed with co3, fe, man, nag
    2. Domain for 1nkx:
      • 711156Domain d1nkxa_: 1nkx A: [91943]
        C-terminal lobe
        complexed with co3, fe, man, nag, zn
    3. Domain for 1sdx:
      • 711161Domain d1sdx.1: 1sdx A:,E: [98812]
        C-terminal lobe
        complexed with co3, man, nag, so4, zn; mutant
    4. Domain for 2alt:
    5. Domain for 2alu:
    6. Domain for 2ays:
    7. Domain for 2b65:
    8. Domain for 2b6d:
    9. Domain for 2doj:
    10. Domain for 2dp8:
    11. Domain for 2dqv:
    12. Domain for 2ds9:
    13. Domain for 2dsf:
    14. Domain for 2dvc:
    15. Domain for 2dwa:
    16. Domain for 2dwh:
    17. Domain for 2dwi:
    18. Domain for 2dwj:
    19. Domain for 2dxr:
    20. Domain for 2dxy:
    21. Domain for 2dyx:
    22. Domain for 2e0s:
    23. Domain for 2e1s:
    24. Domain for 2fa7:
    25. Domain for 2g5j:
    26. Domain for 2g93:
    27. Domain for 2h4i:
    28. Domain for 2hca:
    29. Domain for 2nuv:
    30. Domain for 2nwj:
    31. Domain for 2o1l:
    32. Domain for 2o51:
    33. Domain for 2ocu:
    34. Domain for 2p1s:
    35. Domain for 2px1:
    36. Domain for 2q8j:
  3. 711188Domestic water buffalo (Bubalus arnee bubalis) [TaxId:89462] [53892] (2 PDB entries)
    1. Domains for 1biy:
      1. 711191Domain d1biya1: 1biy A:1-333 [35863]
      2. 711192Domain d1biya2: 1biy A:334-689 [35864]
        complexed with co3, fe
    2. Domains for 1ce2:
      1. 711189Domain d1ce2a1: 1ce2 A:1-333 [35861]
      2. 711190Domain d1ce2a2: 1ce2 A:334-689 [35862]
        complexed with co3, fe
  4. 711193Goat (Capra hircus) [TaxId:9925] [89791] (1 PDB entry)
  5. 711196Horse (Equus caballus) [TaxId:9796] [53893] (6 PDB entries)
    1. Domains for 1b1x:
      1. 711197Domain d1b1xa1: 1b1x A:1-333 [35865]
      2. 711198Domain d1b1xa2: 1b1x A:334-689 [35866]
        complexed with co3, fe
    2. Domains for 1b7u:
      1. 711207Domain d1b7ua1: 1b7u A:1-333 [35873]
      2. 711208Domain d1b7ua2: 1b7u A:334-689 [35874]
    3. Domains for 1b7z:
      1. 711199Domain d1b7za1: 1b7z A:1-333 [35867]
      2. 711200Domain d1b7za2: 1b7z A:334-689 [35868]
        complexed with fe, oxl
    4. Domains for 1f9b:
      1. 711201Domain d1f9ba1: 1f9b A:1-333 [35869]
      2. 711202Domain d1f9ba2: 1f9b A:334-689 [35870]
        complexed with 3id, bct, fe
    5. Domains for 1i6b:
      1. 711205Domain d1i6ba1: 1i6b A:1-333 [66036]
      2. 711206Domain d1i6ba2: 1i6b A:334-689 [66037]
    6. Domains for 1qjm:
      1. 711203Domain d1qjma1: 1qjm A:1-333 [35871]
      2. 711204Domain d1qjma2: 1qjm A:334-689 [35872]
        complexed with co3, sm
  6. 711209Human (Homo sapiens) [TaxId:9606] [53890] (22 PDB entries)
    1. Domains for 1b0l:
      1. 711219Domain d1b0la1: 1b0l A:1-334 [35847]
      2. 711220Domain d1b0la2: 1b0l A:335-691 [35848]
        complexed with crb, mtl; mutant
    2. Domains for 1bka:
      1. 711231Domain d1bkaa1: 1bka A:4-334 [35852]
      2. 711232Domain d1bkaa2: 1bka A:335-691 [35853]
        complexed with fe, oxl
    3. Domains for 1cb6:
      1. 711214Domain d1cb6a1: 1cb6 A:1001-1334 [35840]
      2. 711215Domain d1cb6a2: 1cb6 A:1335-1691 [35841]
        complexed with cl
    4. Domain for 1dsn:
    5. Domain for 1eh3:
      • 711210Domain d1eh3a_: 1eh3 A: [35842]
        N-terminal lobe
        complexed with co3, fe; mutant
    6. Domains for 1fck:
      1. 711221Domain d1fcka1: 1fck A:1-334 [35843]
      2. 711222Domain d1fcka2: 1fck A:335-691 [35844]
        complexed with ce, co3
    7. Domain for 1h43:
      • 711223Domain d1h43a_: 1h43 A: [76672]
        N-terminal lobe
        complexed with co3, fe; mutant
    8. Domain for 1h44:
      • 711213Domain d1h44a_: 1h44 A: [76673]
        N-terminal lobe
        complexed with co3, fe; mutant
    9. Domain for 1h45:
      • 711211Domain d1h45a_: 1h45 A: [76674]
        N-terminal lobe
        complexed with co3, fe; mutant
    10. Domain for 1hse:
    11. Domains for 1l5t:
      1. 711237Domain d1l5ta_: 1l5t A: [73601]
      2. 711238Domain d1l5tb_: 1l5t B: [73602]
        N-terminal lobe
        mutant
    12. Domains for 1lcf:
      1. 711217Domain d1lcfa1: 1lcf A:1-334 [35838]
      2. 711218Domain d1lcfa2: 1lcf A:335-691 [35839]
        complexed with co3, cu, nag, oxl
    13. Domain for 1lct:
    14. Domains for 1lfg:
      1. 711224Domain d1lfga1: 1lfg A:1-334 [35845]
      2. 711225Domain d1lfga2: 1lfg A:335-691 [35846]
        complexed with co3, fe, fuc, nag
    15. Domains for 1lfh:
      1. 711239Domain d1lfha1: 1lfh A:1-334 [35856]
      2. 711240Domain d1lfha2: 1lfh A:335-691 [35857]
        complexed with cl
    16. Domains for 1lfi:
      1. 711227Domain d1lfia1: 1lfi A:1-334 [35850]
      2. 711228Domain d1lfia2: 1lfi A:335-691 [35851]
        complexed with co3, cu, fuc, nag
    17. Domain for 1lgb:
      • 711243Domain d1lgbc_: 1lgb C: [35858]
        Other proteins in same PDB: d1lgb.1
        N2-fragment (one domain fragment)
        complexed with ca, fuc, gal, man, mn, nag
    18. Domains for 1n76:
      1. 711241Domain d1n76a1: 1n76 A:2-334 [80226]
      2. 711242Domain d1n76a2: 1n76 A:335-691 [80227]
        complexed with co3, fe, na
    19. Domains for 1sqy:
      1. 711233Domain d1sqya1: 1sqy A:1-334 [98973]
      2. 711234Domain d1sqya2: 1sqy A:335-691 [98974]
        complexed with co3, fe, nag
    20. Domain for 1vfd:
    21. Domain for 1vfe:
    22. Domains for 2bjj:
      1. 711229Domain d2bjjx1: 2bjj X:3-335 [128622]
        automatically matched to d1n76a1
        complexed with co3, fe, nag
      2. 711230Domain d2bjjx2: 2bjj X:336-692 [128623]
        automatically matched to d1n76a2
        complexed with co3, fe, nag

More info for Protein Lactoferrin from c.94.1.2: Transferrin

Timeline for Protein Lactoferrin from c.94.1.2: Transferrin: