Lineage for Protein: Lactoferrin

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2144291Fold c.94: Periplasmic binding protein-like II [53849] (1 superfamily)
    consists of two similar intertwined domain with 3 layers (a/b/a) each: duplication
    mixed beta-sheet of 5 strands, order 21354; strand 5 is antiparallel to the rest
  4. 2144292Superfamily c.94.1: Periplasmic binding protein-like II [53850] (4 families) (S)
    Similar in architecture to the superfamily I but partly differs in topology
  5. 2145370Family c.94.1.2: Transferrin [53888] (4 protein domains)
    further duplication: composed of two two-domain lobes
  6. 2145371Protein Lactoferrin [53889] (6 species)

Species:

  1. 2145372Camel (Camelus dromedarius) [TaxId:9838] [64195] (2 PDB entries)
    1. Domains for 1dtz:
      1. 2145373Domain d1dtza1: 1dtz A:1-333 [59134]
      2. 2145374Domain d1dtza2: 1dtz A:334-689 [59135]
    2. Domains for 1i6q:
      1. 2145375Domain d1i6qa1: 1i6q A:1-333 [66043]
        complexed with co3, fe
      2. 2145376Domain d1i6qa2: 1i6q A:334-689 [66044]
        complexed with co3, fe
  2. 2145377Cow (Bos taurus) [TaxId:9913] [53891] (19 PDB entries)
    1. Domains for 1blf:
      1. 2145395Domain d1blfa1: 1blf A:5-333 [35859]
        complexed with co3, fe, nag
      2. 2145396Domain d1blfa2: 1blf A:334-689 [35860]
        complexed with co3, fe, nag
    2. Domain for 1nkx:
      • 2145381Domain d1nkxa_: 1nkx A: [91943]
        C-terminal lobe
        complexed with co3, fe, nag, zn
    3. Domain for 1sdx:
    4. Domain for 2alt:
    5. Domain for 2alu:
    6. Domain for 2ays:
    7. Domain for 2b6d:
    8. Domain for 2g5j:
    9. Domain for 2q8j:
    10. Domain for 2qje:
    11. Domain for 2qz1:
    12. Domain for 3fkx:
    13. Domain for 3hwq:
    14. Domain for 3hwv:
    15. Domain for 3hwy:
    16. Domain for 3hwz:
    17. Domains for 4oqo:
      1. 2145393Domain d4oqoa_: 4oqo A: [237718]
        automated match to d2q8ja_
        complexed with nag
      2. 2145394Domain d4oqob_: 4oqo B: [237717]
        automated match to d2q8ja_
        complexed with nag
    18. Domains for 5cry:
      1. 2145397Domain d5crya_: 5cry A: [278056]
        automated match to d1nkxa_
        complexed with bct, bma, fe, nag
      2. 2145398Domain d5cryb_: 5cry B: [278055]
        automated match to d1nkxa_
        complexed with bct, bma, fe, nag
    19. Domains for 5hbc:
      1. 2271329Domain d5hbca_: 5hbc A: [314634]
        automated match to d1nkxa_
        complexed with bct, bma, fe, nag
      2. 2271383Domain d5hbcb_: 5hbc B: [314688]
        automated match to d1nkxa_
        complexed with bct, bma, fe, nag
  3. 2145399Domestic water buffalo (Bubalus arnee bubalis) [TaxId:89462] [53892] (2 PDB entries)
    1. Domains for 1biy:
      1. 2145402Domain d1biya1: 1biy A:1-333 [35863]
        complexed with co3, fe
      2. 2145403Domain d1biya2: 1biy A:334-689 [35864]
        complexed with co3, fe
    2. Domains for 1ce2:
      1. 2145400Domain d1ce2a1: 1ce2 A:1-333 [35861]
        complexed with co3, fe
      2. 2145401Domain d1ce2a2: 1ce2 A:334-689 [35862]
        complexed with co3, fe
  4. 2145404Goat (Capra hircus) [TaxId:9925] [89791] (1 PDB entry)
  5. 2145407Horse (Equus caballus) [TaxId:9796] [53893] (7 PDB entries)
    1. Domains for 1b1x:
      1. 2145408Domain d1b1xa1: 1b1x A:1-333 [35865]
        complexed with co3, fe
      2. 2145409Domain d1b1xa2: 1b1x A:334-689 [35866]
        complexed with co3, fe
    2. Domains for 1b7u:
      1. 2145420Domain d1b7ua1: 1b7u A:1-333 [35873]
      2. 2145421Domain d1b7ua2: 1b7u A:334-689 [35874]
    3. Domains for 1b7z:
      1. 2145412Domain d1b7za1: 1b7z A:1-333 [35867]
        complexed with fe, oxl
      2. 2145413Domain d1b7za2: 1b7z A:334-689 [35868]
        complexed with fe, oxl
    4. Domains for 1f9b:
      1. 2145410Domain d1f9ba1: 1f9b A:1-333 [35869]
        complexed with 3id, bct, fe
      2. 2145411Domain d1f9ba2: 1f9b A:334-689 [35870]
        complexed with 3id, bct, fe
    5. Domains for 1i6b:
      1. 2145418Domain d1i6ba1: 1i6b A:1-333 [66036]
      2. 2145419Domain d1i6ba2: 1i6b A:334-689 [66037]
    6. Domains for 1qjm:
      1. 2145416Domain d1qjma1: 1qjm A:1-333 [35871]
        complexed with co3, sm
      2. 2145417Domain d1qjma2: 1qjm A:334-689 [35872]
        complexed with co3, sm
    7. Domains for 3cr9:
      1. 2145414Domain d3cr9a1: 3cr9 A:1-333 [156943]
        automatically matched to d1b1xa1
        complexed with fe, glc
      2. 2145415Domain d3cr9a2: 3cr9 A:334-689 [156944]
        automatically matched to d1b1xa2
        complexed with fe, glc
  6. 2145422Human (Homo sapiens) [TaxId:9606] [53890] (21 PDB entries)
    1. Domains for 1b0l:
      1. 2145435Domain d1b0la1: 1b0l A:1-334 [35847]
        complexed with co3, fe
      2. 2145436Domain d1b0la2: 1b0l A:335-691 [35848]
        complexed with co3, fe
    2. Domains for 1bka:
      1. 2145445Domain d1bkaa1: 1bka A:4-334 [35852]
        complexed with fe, oxl
      2. 2145446Domain d1bkaa2: 1bka A:335-691 [35853]
        complexed with fe, oxl
    3. Domains for 1cb6:
      1. 2145430Domain d1cb6a1: 1cb6 A:1001-1334 [35840]
        complexed with cl
      2. 2145431Domain d1cb6a2: 1cb6 A:1335-1691 [35841]
        complexed with cl
    4. Domain for 1dsn:
    5. Domain for 1eh3:
    6. Domains for 1fck:
      1. 2145433Domain d1fcka1: 1fck A:1-334 [35843]
        complexed with ce, co3
      2. 2145434Domain d1fcka2: 1fck A:335-691 [35844]
        complexed with ce, co3
    7. Domain for 1h43:
    8. Domain for 1h44:
    9. Domain for 1h45:
    10. Domain for 1hse:
    11. Domains for 1l5t:
      1. 2145447Domain d1l5ta_: 1l5t A: [73601]
        N-terminal lobe
        mutant
      2. 2145448Domain d1l5tb_: 1l5t B: [73602]
        N-terminal lobe
        mutant
    12. Domains for 1lcf:
      1. 2145427Domain d1lcfa1: 1lcf A:1-334 [35838]
        complexed with co3, cu, nag, oxl
      2. 2145428Domain d1lcfa2: 1lcf A:335-691 [35839]
        complexed with co3, cu, nag, oxl
    13. Domain for 1lct:
    14. Domains for 1lfg:
      1. 2145437Domain d1lfga1: 1lfg A:1-334 [35845]
        complexed with co3, fe, fuc, nag
      2. 2145438Domain d1lfga2: 1lfg A:335-691 [35846]
        complexed with co3, fe, fuc, nag
    15. Domains for 1lfh:
      1. 2145450Domain d1lfha1: 1lfh A:1-334 [35856]
        complexed with cl
      2. 2145451Domain d1lfha2: 1lfh A:335-691 [35857]
        complexed with cl
    16. Domains for 1lfi:
      1. 2145440Domain d1lfia1: 1lfi A:1-334 [35850]
        complexed with co3, cu, nag
      2. 2145441Domain d1lfia2: 1lfi A:335-691 [35851]
        complexed with co3, cu, nag
    17. Domain for 1lgb:
      • 2145454Domain d1lgbc_: 1lgb C: [35858]
        Other proteins in same PDB: d1lgb.1
        N2-fragment (one domain fragment)
        complexed with ca, mn
    18. Domains for 1n76:
      1. 2145452Domain d1n76a1: 1n76 A:2-334 [80226]
        complexed with co3, fe, na
      2. 2145453Domain d1n76a2: 1n76 A:335-691 [80227]
        complexed with co3, fe, na
    19. Domains for 1sqy:
      1. 2145442Domain d1sqya1: 1sqy A:1-334 [98973]
        complexed with co3, fe
      2. 2145443Domain d1sqya2: 1sqy A:335-691 [98974]
        complexed with co3, fe
    20. Domain for 1vfd:
    21. Domain for 1vfe:

More info for Protein Lactoferrin from c.94.1.2: Transferrin

Timeline for Protein Lactoferrin from c.94.1.2: Transferrin: