SCOPe 2.05: Family c.90.1.1: Tetrapyrrole methylase

Lineage for Family c.90.1.1: Tetrapyrrole methylase

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.90: Tetrapyrrole methylase [53789] (1 superfamily)
   consists of two non-similar domains
   Domain 1 has parallel sheet of 5 strands, order 32415
   Domain 2 has mixed sheet of 5 strands, order 12534; strands 4 & 5 are antiparallel to the rest

4. Superfamily c.90.1: Tetrapyrrole methylase [53790] (2 families)

5. Family c.90.1.1: Tetrapyrrole methylase [53791] (8 proteins)
   Pfam PF00590

Proteins:

1. Cobalt precorrin-4 methyltransferase CbiF [53792] (1 species)

   • Species Bacillus megaterium [TaxId:1404] [53793] (2 PDB entries)

2. Diphthine synthase, DphB [102684] (3 species)
   diphthamide biosynthesis methyltransferase

   1. Species Aeropyrum pernix [TaxId:56636] [117735] (1 PDB entry)
      SQ Q9YDI2; APE0931

   2. Species Archaeoglobus fulgidus [TaxId:2234] [102685] (1 PDB entry)

   3. Species Pyrococcus horikoshii [TaxId:53953] [142779] (80 PDB entries)
      Uniprot O58456 1-265

3. Hypothetical protein TTHA0667 [142781] (1 species)
   strong sequence similarity to the CysG domain

   • Species Thermus thermophilus [TaxId:274] [142782] (1 PDB entry)
     Uniprot Q5SKH6 2-226

4. Precorrin-6y methylase CbiE [142785] (1 species)

   • Species Archaeoglobus fulgidus [TaxId:2234] [142786] (1 PDB entry)
     Uniprot O29536 1-195

5. Putative methytransferase BT4190 [142783] (1 species)

   • Species Bacteroides thetaiotaomicron [TaxId:818] [142784] (1 PDB entry)
     Uniprot Q8A031 2-234

6. Siroheme synthase CysG, domains 4 and 5 [102682] (1 species)

   • Species Salmonella typhimurium [TaxId:90371] [102683] (3 PDB entries)

7. Uroporphyrin-III C-methyltransferase (SUMT, UROM, CobA) [117736] (2 species)

   1. Species Pseudomonas denitrificans [TaxId:43306] [117737] (1 PDB entry)
      Uniprot P21631

   2. Species Thermus thermophilus [TaxId:274] [142780] (1 PDB entry)
      Uniprot Q53WA2 1-235

8. automated matches [190790] (3 species)
   not a true protein

   1. Species Bacteroides thetaiotaomicron [TaxId:226186] [188101] (1 PDB entry)

   2. Species Thermus thermophilus HB8 [TaxId:300852] [188045] (2 PDB entries)

   3. Species Thermus thermophilus [TaxId:274] [188055] (1 PDB entry)

More info for Family c.90.1.1: Tetrapyrrole methylase

Timeline for Family c.90.1.1: Tetrapyrrole methylase:

• Family c.90.1.1: Tetrapyrrole methylase first appeared (with stable ids) in SCOP 1.55, called Family c.90.1.1: Cobalt precorrin-4 methyltransferase CbiF
  
• Family c.90.1.1: Tetrapyrrole methylase appears in SCOPe 2.04
  
• Family c.90.1.1: Tetrapyrrole methylase appears in SCOPe 2.06
  
• Family c.90.1.1: Tetrapyrrole methylase appears in the current release, SCOPe 2.08