SCOPe 2.07: Family c.82.1.1: ALDH-like

Lineage for Family c.82.1.1: ALDH-like

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.82: ALDH-like [53719] (1 superfamily)
   consists of two similar domains with 3 layers (a/b/a) each; duplication
   core: parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.82.1: ALDH-like [53720] (3 families)
   binds NAD differently from other NAD(P)-dependent oxidoreductases

5. Family c.82.1.1: ALDH-like [53721] (6 proteins)

Proteins:

1. 1-pyrroline-5-carboxylate dehydrogenase [102675] (1 species)

   • Species Thermus thermophilus [TaxId:274] [102676] (1 PDB entry)

2. Aldehyde reductase (dehydrogenase), ALDH [53722] (9 species)

   1. Species Baltic cod (Gadus callarias) [TaxId:8053] [53728] (2 PDB entries)

   2. Species Cow (Bos taurus), mitochondrial [TaxId:9913] [53725] (2 PDB entries)

   3. Species Elephant shrew (Elephantulus edwardii) [TaxId:28737] [89780] (1 PDB entry)
      cytosolic form; eta-crystallin

   4. Species Human (Homo sapiens), mitochondrial [TaxId:9606] [53726] (27 PDB entries)
      Uniprot P05091

   5. Species Norway rat (Rattus norvegicus) [TaxId:10116] [53723] (1 PDB entry)

   6. Species Norway rat (Rattus norvegicus), retinal type II [TaxId:10116] [53724] (1 PDB entry)

   7. Species Sheep (Ovis aries) [TaxId:9940] [53727] (3 PDB entries)

   8. Species Streptococcus mutans [TaxId:1309] [53729] (4 PDB entries)

   9. Species Vibrio harveyi [TaxId:669] [53730] (4 PDB entries)

3. Gamma-glutamyl phosphate reductase [89781] (2 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [110731] (1 PDB entry)
      Uniprot P54885

   2. Species Thermotoga maritima [TaxId:2336] [89782] (1 PDB entry)
      TM0293

4. Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase GapN [82538] (1 species)

   • Species Thermoproteus tenax [TaxId:2271] [82539] (8 PDB entries)
     Uniprot O57693

5. Putative betaine aldehyde dehydrogenase YdcW [117733] (1 species)

   • Species Escherichia coli [TaxId:562] [117734] (2 PDB entries)
     Uniprot P77674

6. automated matches [190401] (5 species)
   not a true protein

   1. Species Human (Homo sapiens) [TaxId:9606] [189906] (28 PDB entries)

   2. Species Sheep (Ovis aries) [TaxId:9940] [276868] (1 PDB entry)

   3. Species Streptococcus mutans [TaxId:1309] [187673] (3 PDB entries)

   4. Species Thermus thermophilus HB8 [TaxId:300852] [187273] (15 PDB entries)

   5. Species Thermus thermophilus [TaxId:262724] [197417] (1 PDB entry)

More info for Family c.82.1.1: ALDH-like

Timeline for Family c.82.1.1: ALDH-like:

• Family c.82.1.1: ALDH-like first appeared (with stable ids) in SCOP 1.55, called Family c.82.1.1: Aldehyde reductase (dehydrogenase), ALDH
  
• Family c.82.1.1: ALDH-like appears in SCOPe 2.06
  
• Family c.82.1.1: ALDH-like appears in the current release, SCOPe 2.08