SCOP 1.73: Family c.82.1.1: ALDH-like

Lineage for Family c.82.1.1: ALDH-like

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.82: ALDH-like [53719] (1 superfamily)
   consists of two similar domains with 3 layers (a/b/a) each; duplication
   core: parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.82.1: ALDH-like [53720] (2 families)
   binds NAD differently from other NAD(P)-dependent oxidoreductases

5. Family c.82.1.1: ALDH-like [53721] (5 proteins)

Proteins:

1. 1-pyrroline-5-carboxylate dehydrogenase [102675] (1 species)

   • Species Thermus thermophilus [TaxId:274] [102676] (1 PDB entry)

2. Aldehyde reductase (dehydrogenase), ALDH [53722] (9 species)

   1. Species Baltic cod (Gadus callarias) [TaxId:8053] [53728] (2 PDB entries)

   2. Species Cow (Bos taurus), mitochondrial [TaxId:9913] [53725] (2 PDB entries)

   3. Species Elephant shrew (Elephantulus edwardii) [TaxId:28737] [89780] (1 PDB entry)
      cytosolic form; eta-crystallin

   4. Species Human (Homo sapiens), mitochondrial [TaxId:9606] [53726] (10 PDB entries)

   5. Species Rat (Rattus norvegicus) [TaxId:10116] [53723] (1 PDB entry)

   6. Species Rat (Rattus norvegicus), retinal type II [TaxId:10116] [53724] (1 PDB entry)

   7. Species Sheep (Ovis aries) [TaxId:9940] [53727] (1 PDB entry)

   8. Species Streptococcus mutans [TaxId:1309] [53729] (4 PDB entries)

   9. Species Vibrio harveyi [TaxId:669] [53730] (2 PDB entries)

3. Gamma-glutamyl phosphate reductase [89781] (2 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [110731] (1 PDB entry)

   2. Species Thermotoga maritima [TaxId:2336] [89782] (1 PDB entry)
      TM0293

4. Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase GapN [82538] (1 species)

   • Species Archaeon Thermoproteus tenax [TaxId:2271] [82539] (8 PDB entries)

5. Putative betaine aldehyde dehydrogenase YdcW [117733] (1 species)

   • Species Escherichia coli [TaxId:562] [117734] (2 PDB entries)

More info for Family c.82.1.1: ALDH-like

Timeline for Family c.82.1.1: ALDH-like:

• Family c.82.1.1: ALDH-like first appeared (with stable ids) in SCOP 1.55, called Family c.82.1.1: Aldehyde reductase (dehydrogenase), ALDH
  
• Family c.82.1.1: ALDH-like appears in SCOP 1.71
  
• Family c.82.1.1: ALDH-like appears in SCOP 1.75
  
• Family c.82.1.1: ALDH-like appears in the current release, SCOPe 2.08