Class c: Alpha and beta proteins (a/b) [51349] (141 folds) |
Fold c.80: SIS domain [53696] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 5 strands, order 21345 |
Superfamily c.80.1: SIS domain [53697] (3 families) |
Family c.80.1.2: Phosphoglucose isomerase, PGI [53701] (1 protein) permutation of the double-SIS domain fold |
Phosphoglucose isomerase, PGI [53702] (6 species) moonlights as neuroleukin, autocrine motility factor, and differentiation mediator |
Species Bacillus stearothermophilus [TaxId:1422] [53704] (4 PDB entries) |
Species Human (Homo sapiens) [TaxId:9606] [64176] (5 PDB entries) |
Species Leishmania mexicana [TaxId:5665] [110728] (2 PDB entries) |
Species Mouse (Mus musculus) [TaxId:10090] [117732] (3 PDB entries) |
Species Pig (Sus scrofa) [TaxId:9823] [75316] (2 PDB entries) |
Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [53703] (7 PDB entries) |
Timeline for Family c.80.1.2: Phosphoglucose isomerase, PGI: