SCOPe 2.08: Family c.80.1.1: double-SIS domain

Lineage for Family c.80.1.1: double-SIS domain

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.80: SIS domain [53696] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 5 strands, order 21345

4. Superfamily c.80.1: SIS domain [53697] (4 families)

5. Family c.80.1.1: double-SIS domain [53698] (5 proteins)
   duplication: consists of two SIS domains related by pseudo dyad

Proteins:

1. 'Isomerase domain' of glucosamine 6-phosphate synthase (GLMS) [53699] (2 species)

   1. Species Escherichia coli [TaxId:562] [53700] (6 PDB entries)

   2. Species Escherichia coli [TaxId:83333] [421256] (1 PDB entry)

2. Glucose-6-phosphate isomerase, conjectural [110726] (1 species)

   • Species Pyrobaculum aerophilum [TaxId:13773] [110727] (4 PDB entries)
     Uniprot Q8ZWV0

3. Glucose-6-phosphate isomerase-like protein TTHA1346 [117730] (1 species)

   • Species Thermus thermophilus [TaxId:274] [117731] (1 PDB entry)
     Uniprot Q5SIM3

4. Hypothetical protein TM0813 [75314] (1 species)

   • Species Thermotoga maritima [TaxId:2336] [75315] (1 PDB entry)

5. automated matches [227069] (2 species)
   not a true protein

   1. Species Escherichia coli [TaxId:562] [233109] (5 PDB entries)

   2. Species Francisella tularensis [TaxId:119856] [226197] (1 PDB entry)

More info for Family c.80.1.1: double-SIS domain

Timeline for Family c.80.1.1: double-SIS domain:

• Family c.80.1.1: double-SIS domain first appeared (with stable ids) in SCOP 1.55, called Family c.80.1.1: "Isomerase domain" of glucosamine 6-phosphate synthase (GLMS)
  
• Family c.80.1.1: double-SIS domain appears in SCOPe 2.07