Class c: Alpha and beta proteins (a/b) [51349] (134 folds) |
Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily) consists of two intertwined (sub)domains related by pseudo dyad; duplication 3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest |
Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (5 families) the constituent families form similar dimers |
Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (3 proteins) the active site is between the two identical subunits |
Protein Isocitrate dehydrogenase, ICDH [53668] (2 species) |
Bacillus subtilis [TaxId:1423] [64171] (1 PDB entry) |
Domain d1hqsa_: 1hqs A: [61154] |
Domain d1hqsb_: 1hqs B: [61155] complexed with cit, pgq, pgr |
Escherichia coli [TaxId:562] [53669] (26 PDB entries) |
Domain d1ai2__: 1ai2 - [35067] complexed with ica, nap |
Domain d1ai3__: 1ai3 - [35066] complexed with itm, ndo |
Domain d1bl5__: 1bl5 - [35083] complexed with akg, mg, nap |
Domain d1cw1a_: 1cw1 A: [35069] complexed with ici, mn, so4; mutant |
Domain d1cw4a_: 1cw4 A: [35068] complexed with akg, mn, so4; mutant |
Domain d1cw7a_: 1cw7 A: [35087] complexed with ici, mg, so4 |
Domain d1gro__: 1gro - [35079] complexed with ict, mg; mutant |
Domain d1grp__: 1grp - [35077] complexed with ict, mg; mutant |
Domain d1hj6a_: 1hj6 A: [35070] complexed with gol, ipm, mg, nap; mutant |
Domain d1idc__: 1idc - [35073] complexed with mg, oxs; mutant |
Domain d1idd__: 1idd - [35084] mutant |
Domain d1ide__: 1ide - [35082] complexed with ict, mg, nap; mutant |
Domain d1idf__: 1idf - [35086] mutant |
Domain d1ika__: 1ika - [35085] complexed with akg, ca |
Domain d1iso__: 1iso - [35065] complexed with nad, so4; mutant |
Domain d1p8fa_: 1p8f A: [87943] complexed with gol, ici, mg, so4 |
Domain d1pb1a_: 1pb1 A: [88014] complexed with gol, ici, so4 |
Domain d1pb3a_: 1pb3 A: [88015] complexed with gol, so4 |
Domain d1sjs__: 1sjs - [35071] |
Domain d3icd__: 3icd - [35078] |
Domain d4icd__: 4icd - [35074] complexed with pho |
Domain d5icd__: 5icd - [35080] complexed with ict, mg |
Domain d6icd__: 6icd - [35081] mutant |
Domain d7icd__: 7icd - [35072] mutant |
Domain d8icd__: 8icd - [35076] complexed with ict, mg; mutant |
Domain d9icd__: 9icd - [35075] complexed with nap |
Timeline for Protein Isocitrate dehydrogenase, ICDH from c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases: