Lineage for Protein: 3-isopropylmalate dehydrogenase, IPMDH

  1. Root: SCOP 1.69
  2. 473232Class c: Alpha and beta proteins (a/b) [51349] (136 folds)
  3. 493010Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudo dyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. 493011Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (5 families) (S)
    the constituent families form similar dimers
  5. 493012Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (3 proteins)
    the active site is between the two identical subunits
  6. 493013Protein 3-isopropylmalate dehydrogenase, IPMDH [53661] (7 species)

Species:

  1. 493014Bacillus coagulans [TaxId:1398] [53664] (1 PDB entry)
  2. 493017Chimera (Thermus thermophilus) and (Bacillus subtilis) [TaxId:274] [53663] (2 PDB entries)
    1. Domain for 1xac:
    2. Domain for 1xad:
  3. 493020Escherichia coli [TaxId:562] [53667] (1 PDB entry)
  4. 493023Salmonella typhimurium [TaxId:90371] [53666] (1 PDB entry)
  5. 493026Thermotoga maritima [TaxId:243274] [110714] (1 PDB entry)
  6. 493028Thermus thermophilus [TaxId:274] [53662] (14 PDB entries)
    1. Domains for 1dpz:
      1. 493046Domain d1dpza_: 1dpz A: [35053]
      2. 493047Domain d1dpzb_: 1dpz B: [35054]
    2. Domains for 1dr0:
      1. 493040Domain d1dr0a_: 1dr0 A: [35045]
      2. 493041Domain d1dr0b_: 1dr0 B: [35046]
    3. Domains for 1dr8:
      1. 493048Domain d1dr8a_: 1dr8 A: [35051]
      2. 493049Domain d1dr8b_: 1dr8 B: [35052]
    4. Domain for 1g2u:
    5. Domains for 1gc8:
      1. 493038Domain d1gc8a_: 1gc8 A: [35042]
      2. 493039Domain d1gc8b_: 1gc8 B: [35043]
    6. Domain for 1gc9:
    7. Domain for 1hex:
    8. Domain for 1idm:
    9. Domain for 1ipd:
    10. Domains for 1osi:
      1. 493042Domain d1osia_: 1osi A: [35047]
      2. 493043Domain d1osib_: 1osi B: [35048]
      3. 493044Domain d1osic_: 1osi C: [35049]
      4. 493045Domain d1osid_: 1osi D: [35050]
    11. Domains for 1osj:
      1. 493034Domain d1osja_: 1osj A: [35039]
      2. 493035Domain d1osjb_: 1osj B: [35040]
    12. Domain for 1wal:
    13. Domain for 1xaa:
    14. Domain for 1xab:
  7. 493051Thiobacillus ferrooxidans [TaxId:920] [53665] (1 PDB entry)

More info for Protein 3-isopropylmalate dehydrogenase, IPMDH from c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases

Timeline for Protein 3-isopropylmalate dehydrogenase, IPMDH from c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases: