Lineage for Protein: 3-isopropylmalate dehydrogenase, IPMDH

  1. Root: SCOP 1.63
  2. 235644Class c: Alpha and beta proteins (a/b) [51349] (117 folds)
  3. 249486Fold c.77: Isocitrate/Isopropylmalate dehydrogenases [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudodyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. 249487Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenases [53659] (2 families) (S)
  5. 249488Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (3 proteins)
    the active site is between the two identical subunits
  6. 249489Protein 3-isopropylmalate dehydrogenase, IPMDH [53661] (6 species)

Species:

  1. 249490Bacillus coagulans [TaxId:1398] [53664] (1 PDB entry)
  2. 249493Chimera (Thermus thermophilus) and (Bacillus subtilis) [TaxId:274] [53663] (2 PDB entries)
    1. Domain for 1xac:
    2. Domain for 1xad:
  3. 249496Escherichia coli [TaxId:562] [53667] (1 PDB entry)
  4. 249499Salmonella typhimurium [TaxId:90371] [53666] (1 PDB entry)
  5. 249502Thermus thermophilus [TaxId:274] [53662] (14 PDB entries)
    1. Domains for 1dpz:
      1. 249521Domain d1dpza_: 1dpz A: [35053]
      2. 249522Domain d1dpzb_: 1dpz B: [35054]
    2. Domains for 1dr0:
      1. 249515Domain d1dr0a_: 1dr0 A: [35045]
      2. 249516Domain d1dr0b_: 1dr0 B: [35046]
    3. Domains for 1dr8:
      1. 249523Domain d1dr8a_: 1dr8 A: [35051]
      2. 249524Domain d1dr8b_: 1dr8 B: [35052]
    4. Domain for 1g2u:
    5. Domains for 1gc8:
      1. 249512Domain d1gc8a_: 1gc8 A: [35042]
      2. 249513Domain d1gc8b_: 1gc8 B: [35043]
        mutant
    6. Domain for 1gc9:
    7. Domain for 1hex:
    8. Domain for 1idm:
    9. Domain for 1ipd:
    10. Domains for 1osi:
      1. 249517Domain d1osia_: 1osi A: [35047]
      2. 249518Domain d1osib_: 1osi B: [35048]
      3. 249519Domain d1osic_: 1osi C: [35049]
      4. 249520Domain d1osid_: 1osi D: [35050]
    11. Domains for 1osj:
      1. 249509Domain d1osja_: 1osj A: [35039]
      2. 249510Domain d1osjb_: 1osj B: [35040]
        mutant
    12. Domain for 1wal:
    13. Domain for 1xaa:
    14. Domain for 1xab:
  6. 249525Thiobacillus ferrooxidans [TaxId:920] [53665] (1 PDB entry)

More info for Protein 3-isopropylmalate dehydrogenase, IPMDH from c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases

Timeline for Protein 3-isopropylmalate dehydrogenase, IPMDH from c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases: