Lineage for Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases

  1. Root: SCOP 1.67
  2. 383641Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
  3. 401891Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudo dyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. 401892Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (5 families) (S)
    the constituent families form similar dimers
  5. 401893Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (3 proteins)
    the active site is between the two identical subunits

Proteins:

  1. 4018943-isopropylmalate dehydrogenase, IPMDH [53661] (6 species)
    1. 401895Species Bacillus coagulans [TaxId:1398] [53664] (1 PDB entry)
    2. 401898Species Chimera (Thermus thermophilus) and (Bacillus subtilis) [TaxId:274] [53663] (2 PDB entries)
    3. 401901Species Escherichia coli [TaxId:562] [53667] (1 PDB entry)
    4. 401904Species Salmonella typhimurium [TaxId:90371] [53666] (1 PDB entry)
    5. 401907Species Thermus thermophilus [TaxId:274] [53662] (14 PDB entries)
    6. 401930Species Thiobacillus ferrooxidans [TaxId:920] [53665] (1 PDB entry)
  2. 401933Isocitrate dehydrogenase, ICDH [53668] (2 species)
    1. 401934Species Bacillus subtilis [TaxId:1423] [64171] (1 PDB entry)
    2. 401937Species Escherichia coli [TaxId:562] [53669] (26 PDB entries)
  3. 401964NADP-dependent isocitrate dehydrogenase [82524] (1 species)

More info for Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases

Timeline for Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases: