SCOPe 2.07: Protein: UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD

Lineage for Protein: UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD

Root: SCOPe 2.07
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.72: Ribokinase-like [53612] (3 superfamilies)
core: 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest
potential superfamily: members of this fold have similar functions but different ATP-binding sites

Superfamily c.72.2: MurD-like peptide ligases, catalytic domain [53623] (3 families)
has extra strand located between strands 1 and 2
Family c.72.2.1: MurCDEF [53624] (5 proteins)
automatically mapped to Pfam PF08245
Protein UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD [53625] (1 species)

Species:

Escherichia coli [TaxId:562] [53626] (7 PDB entries)
1. Domain for 1e0d:
  - Domain d1e0da3: 1e0d A:94-297 [34959]
    Other proteins in same PDB: d1e0da1, d1e0da2
    complexed with so4
2. Domain for 1eeh:
  - Domain d1eeha3: 1eeh A:94-297 [34958]
    Other proteins in same PDB: d1eeha1, d1eeha2
    complexed with uma
3. Domain for 1uag:
  - Domain d1uaga3: 1uag A:94-297 [34957]
    Other proteins in same PDB: d1uaga1, d1uaga2
    complexed with so4, uma
4. Domain for 2uag:
  - Domain d2uaga3: 2uag A:94-297 [34954]
    Other proteins in same PDB: d2uaga1, d2uaga2
    complexed with adp, mg, uma
5. Domain for 3uag:
  - Domain d3uaga3: 3uag A:94-297 [34956]
    Other proteins in same PDB: d3uaga1, d3uaga2
    complexed with adp, epe, mn, uma
6. Domain for 4uag:
  - Domain d4uaga3: 4uag A:94-297 [34955]
    Other proteins in same PDB: d4uaga1, d4uaga2
    complexed with so4, uag, unx
7. Domain for 5a5e:
  - Domain d5a5ea2: 5a5e A:94-297 [315198]
    Other proteins in same PDB: d5a5ea1, d5a5ea3
    automated match to d2uaga3
    complexed with mpd, ni, so4

More info for Protein UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD from c.72.2.1: MurCDEF

Timeline for Protein UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD from c.72.2.1: MurCDEF:

Protein UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD from c.72.2.1: MurCDEF first appeared (with stable ids) in SCOP 1.55, called Protein UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase, gene MurD from c.72.2.1: MurD/MurF
Protein UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD from c.72.2.1: MurCDEF appears in SCOPe 2.06
Protein UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD from c.72.2.1: MurCDEF appears in the current release, SCOPe 2.08