Lineage for Family c.72.2.1: MurCDEF

  1. Root: SCOP 1.63
  2. 235644Class c: Alpha and beta proteins (a/b) [51349] (117 folds)
  3. 249219Fold c.72: Ribokinase-like [53612] (2 superfamilies)
    core: 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest
    potential superfamily: members of this fold have similar functions but different ATP-binding sites
  4. 249292Superfamily c.72.2: MurD-like peptide ligases, catalytic domain [53623] (2 families) (S)
    has extra strand located between strands 1 and 2
  5. 249293Family c.72.2.1: MurCDEF [53624] (4 proteins)

Proteins:

  1. 249294UDP-murNac-tripeptide D-alanyl-D-alanine-adding enzyme MurF [53627] (1 species)
  2. 249298UDP-N-acetylmuramate-alanine ligase MurC [82520] (1 species)
  3. 249301UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD [53625] (1 species)
  4. 249309UDP-N-acetylmuramyl tripeptide synthetase MurE [64150] (1 species)

More info for Family c.72.2.1: MurCDEF

Timeline for Family c.72.2.1: MurCDEF: