Class c: Alpha and beta proteins (a/b) [51349] (141 folds) |
Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily) 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest |
Superfamily c.71.1: Dihydrofolate reductase-like [53597] (2 families) |
Family c.71.1.1: Dihydrofolate reductases [53598] (3 proteins) |
Protein Dihydrofolate reductases, eukaryotic type [53605] (4 species) |
Species Human (Homo sapiens) [TaxId:9606] [53607] (25 PDB entries) |
Domain d1boza_: 1boz A: [34905] complexed with coe; mutant |
Domain d1dhfa_: 1dhf A: [34910] |
Domain d1dhfb_: 1dhf B: [34911] complexed with fol |
Domain d1dlra_: 1dlr A: [34909] complexed with mxa, ndp; mutant |
Domain d1dlsa_: 1dls A: [34906] complexed with mtx, ndp; mutant |
Domain d1drfa_: 1drf A: [34907] complexed with fol, so4 |
Domain d1hfpa_: 1hfp A: [34904] complexed with mot, nap; mutant |
Domain d1hfqa_: 1hfq A: [34903] complexed with mot, nap; mutant |
Domain d1hfra_: 1hfr A: [34908] complexed with mot, nap |
Domain d1kmsa_: 1kms A: [72756] complexed with lih, ndp, sul |
Domain d1kmva_: 1kmv A: [72757] complexed with dms, lii, ndp, sul |
Domain d1mvsa_: 1mvs A: [85156] complexed with dtm, so4 |
Domain d1mvta_: 1mvt A: [85157] complexed with dtm, so4 |
Domain d1ohja_: 1ohj A: [34914] complexed with cop, ndp |
Domain d1ohka_: 1ohk A: [34915] complexed with cop, ndp |
Domain d1pd8a_: 1pd8 A: [94515] complexed with co4, ndp |
Domain d1pd9a_: 1pd9 A: [94516] complexed with co4, sul |
Domain d1pdba_: 1pdb A: [94517] |
Domain d1s3ua_: 1s3u A: [98464] complexed with sul, tqd |
Domain d1s3va_: 1s3v A: [98465] complexed with sul, tqd |
Domain d1s3wa_: 1s3w A: [98466] complexed with nap, tqt |
Domain d1u72a1: 1u72 A:1-186 [119614] automatically matched to d1drf__ complexed with mtx, ndp |
Domain d1yhoa1: 1yho A:1-186 [123179] automatically matched to d1drf__ complexed with ndp, trr |
Domain d2c2sa1: 2c2s A:1-186 [129682] automatically matched to d1drf__ complexed with 34b, gol, ndp |
Domain d2c2sb1: 2c2s B:1-186 [129683] automatically matched to d1drf__ complexed with 34b, gol, ndp |
Domain d2c2ta1: 2c2t A:1-186 [129684] automatically matched to d1drf__ complexed with 39b, 39e, gol, ndp |
Domain d2c2tb1: 2c2t B:1-186 [129685] automatically matched to d1drf__ complexed with 39b, 39e, gol, ndp |
Domain d2dhfa_: 2dhf A: [34912] |
Domain d2dhfb_: 2dhf B: [34913] complexed with dzf |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.71.1.1 Dihydrofolate reductases, eukaryotic type: