Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2136820Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2136821Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2136822Family c.71.1.1: Dihydrofolate reductases [53598] (4 protein domains)
  6. 2137011Protein Dihydrofolate reductases, eukaryotic type [53605] (7 species)
  7. 2137059Species Human (Homo sapiens) [TaxId:9606] [53607] (73 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1boz:
  2. Domain(s) for 1dhf:
    1. 2137121Domain d1dhfa_: 1dhf A: [34910]
      complexed with fol
    2. 2137122Domain d1dhfb_: 1dhf B: [34911]
      complexed with fol
  3. Domain(s) for 1dlr:
  4. Domain(s) for 1dls:
  5. Domain(s) for 1drf:
  6. Domain(s) for 1hfp:
  7. Domain(s) for 1hfq:
  8. Domain(s) for 1hfr:
  9. Domain(s) for 1kms:
  10. Domain(s) for 1kmv:
  11. Domain(s) for 1mvs:
  12. Domain(s) for 1mvt:
  13. Domain(s) for 1ohj:
  14. Domain(s) for 1ohk:
  15. Domain(s) for 1pd8:
  16. Domain(s) for 1pd9:
  17. Domain(s) for 1pdb:
  18. Domain(s) for 1s3u:
  19. Domain(s) for 1s3v:
  20. Domain(s) for 1s3w:
  21. Domain(s) for 1u71:
  22. Domain(s) for 1u72:
  23. Domain(s) for 1yho:
  24. Domain(s) for 2c2s:
    1. 2137069Domain d2c2sa_: 2c2s A: [129682]
      automated match to d1drf__
      complexed with 34b, gol, ndp
    2. 2137070Domain d2c2sb_: 2c2s B: [129683]
      automated match to d1drf__
      complexed with 34b, gol, ndp
  25. Domain(s) for 2c2t:
    1. 2137075Domain d2c2ta_: 2c2t A: [129684]
      automated match to d1drf__
      complexed with 39b, 39e, gol, ndp
    2. 2137076Domain d2c2tb_: 2c2t B: [129685]
      automated match to d1drf__
      complexed with 39b, 39e, gol, ndp
  26. Domain(s) for 2dhf:
    1. 2137127Domain d2dhfa_: 2dhf A: [34912]
      complexed with dzf
    2. 2137128Domain d2dhfb_: 2dhf B: [34913]
      complexed with dzf
  27. Domain(s) for 2w3a:
    1. 2137079Domain d2w3aa_: 2w3a A: [169035]
      automated match to d1dlra_
      complexed with gol, ndp, so4, top
    2. 2137080Domain d2w3ab_: 2w3a B: [169036]
      automated match to d1dlra_
      complexed with gol, ndp, so4, top
  28. Domain(s) for 2w3b:
    1. 2137063Domain d2w3ba_: 2w3b A: [169037]
      automated match to d1dlra_
      complexed with fol, k, ndp, vg9
    2. 2137064Domain d2w3bb_: 2w3b B: [169038]
      automated match to d1dlra_
      complexed with fol, k, ndp, vg9
  29. Domain(s) for 2w3m:
    1. 2137083Domain d2w3ma_: 2w3m A: [169045]
      automated match to d1dlra_
      complexed with fol, ndp
    2. 2137084Domain d2w3mb_: 2w3m B: [169046]
      automated match to d1dlra_
      complexed with fol, ndp
  30. Domain(s) for 3eig:
  31. Domain(s) for 3f8y:
  32. Domain(s) for 3f8z:
  33. Domain(s) for 3f91:
  34. Domain(s) for 3fs6:
  35. Domain(s) for 3ghc:
  36. Domain(s) for 3ghv:
  37. Domain(s) for 3ghw:
  38. Domain(s) for 3gi2:
  39. Domain(s) for 3gyf:
  40. Domain(s) for 3l3r:
  41. Domain(s) for 3ntz:
  42. Domain(s) for 3nu0:
  43. Domain(s) for 3nxo:
  44. Domain(s) for 3nxr:
  45. Domain(s) for 3nxt:
  46. Domain(s) for 3nxv:
  47. Domain(s) for 3nxx:
  48. Domain(s) for 3nxy:
  49. Domain(s) for 3nzd:
  50. Domain(s) for 3oaf:
  51. Domain(s) for 3s7a:
  52. Domain(s) for 4ddr:
  53. Domain(s) for 4g95:
  54. Domain(s) for 4kak:
    1. 2137109Domain d4kaka_: 4kak A: [228206]
      automated match to d1kmva_
      complexed with 06u, ca, eoh, ndp
    2. 2137110Domain d4kakb_: 4kak B: [228207]
      automated match to d1kmva_
      complexed with 06u, ca, eoh, ndp
  55. Domain(s) for 4kbn:
    1. 2137115Domain d4kbna_: 4kbn A: [228209]
      automated match to d1kmva_
      complexed with 25u, cl, eoh, mg, ndp, nh4, sr
    2. 2137116Domain d4kbnb_: 4kbn B: [228208]
      automated match to d1kmva_
      complexed with 25u, cl, eoh, mg, ndp, nh4, sr
  56. Domain(s) for 4kd7:
    1. 2137130Domain d4kd7a_: 4kd7 A: [228211]
      automated match to d1kmva_
      complexed with 9dr, ndp, so4
    2. 2137131Domain d4kd7b_: 4kd7 B: [228210]
      automated match to d1kmva_
      complexed with 9dr, ndp, so4
  57. Domain(s) for 4keb:
    1. 2137085Domain d4keba_: 4keb A: [228213]
      automated match to d1kmva_
      complexed with 1qz, fol, ndp
    2. 2137086Domain d4kebb_: 4keb B: [228212]
      automated match to d1kmva_
      complexed with 1qz, fol, ndp
  58. Domain(s) for 4kfj:
    1. 2137103Domain d4kfja_: 4kfj A: [228220]
      automated match to d1kmva_
      complexed with 1r0, cl, eoh, fol, mg, ndp
    2. 2137104Domain d4kfjb_: 4kfj B: [228221]
      automated match to d1kmva_
      complexed with 1r0, cl, eoh, fol, mg, ndp
  59. Domain(s) for 4m6j:
  60. Domain(s) for 4m6k:
  61. Domain(s) for 4m6l:
  62. Domain(s) for 4qhv:
  63. Domain(s) for 4qjc:
  64. Domain(s) for 5hpb:
  65. Domain(s) for 5hqy:
  66. Domain(s) for 5hqz:
  67. Domain(s) for 5hsr:
  68. Domain(s) for 5hsu:
  69. Domain(s) for 5ht4:
  70. Domain(s) for 5ht5:
  71. Domain(s) for 5hui:
  72. Domain(s) for 5hvb:
  73. Domain(s) for 5hve:

More info for Species Human (Homo sapiens) [TaxId:9606] from c.71.1.1 Dihydrofolate reductases, eukaryotic type

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.71.1.1 Dihydrofolate reductases, eukaryotic type: