SCOPe 2.08: Family c.68.1.5: UDP-glucose pyrophosphorylase

Lineage for Family c.68.1.5: UDP-glucose pyrophosphorylase

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.68: Nucleotide-diphospho-sugar transferases [53447] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 7 strands, order 3214657; strand 6 is antiparallel to the rest

4. Superfamily c.68.1: Nucleotide-diphospho-sugar transferases [53448] (20 families)

5. Family c.68.1.5: UDP-glucose pyrophosphorylase [53461] (4 proteins)

Proteins:

1. N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain [53462] (3 species)

   1. Species Escherichia coli [TaxId:562] [53463] (6 PDB entries)

   2. Species Mycobacterium tuberculosis [TaxId:1773] [256398] (1 PDB entry)

   3. Species Pneumococcus (Streptococcus pneumoniae) [TaxId:1313] [64134] (5 PDB entries)

2. UDP-glucose pyrophosphorylase 2 (UDPGP 2) [142686] (1 species)

   • Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [142687] (4 PDB entries)
     Uniprot Q9M9P3 6-383

3. UDP-N-acetylglucosamine pyrophosphorylase [75280] (3 species)

   1. Species Human (Homo sapiens), AGX1 [TaxId:9606] [75281] (2 PDB entries)

   2. Species Human (Homo sapiens), AGX2 [TaxId:9606] [82490] (2 PDB entries)

   3. Species Mouse (Mus musculus), AGX2 [TaxId:10090] [117698] (1 PDB entry)
      Uniprot Q91YN5

4. automated matches [226998] (5 species)
   not a true protein

   1. Species Human (Homo sapiens) [TaxId:9606] [407400] (1 PDB entry)

   2. Species Pneumococcus (Streptococcus pneumoniae) [TaxId:1313] [226302] (2 PDB entries)

   3. Species Saccharum hybrid [TaxId:193079] [348074] (1 PDB entry)

   4. Species Yersinia pestis [TaxId:386656] [232197] (1 PDB entry)

   5. Species Yersinia pseudotuberculosis [TaxId:214092] [234414] (1 PDB entry)

More info for Family c.68.1.5: UDP-glucose pyrophosphorylase

Timeline for Family c.68.1.5: UDP-glucose pyrophosphorylase:

• Family c.68.1.5: UDP-glucose pyrophosphorylase first appeared (with stable ids) in SCOP 1.55, called Family c.68.1.5: N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain
  
• Family c.68.1.5: UDP-glucose pyrophosphorylase appears in SCOPe 2.07