Lineage for Protein: Catechol O-methyltransferase, COMT

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2129295Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. 2129296Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families) (S)
  5. 2129297Family c.66.1.1: COMT-like [53336] (4 protein domains)
  6. 2129308Protein Catechol O-methyltransferase, COMT [53337] (2 species)

Species:

  1. 2129309Human (Homo sapiens) [TaxId:9606] [267759] (10 PDB entries)
    1. Domain for 3a7e:
    2. Domain for 3bwm:
    3. Domain for 3bwy:
    4. Domain for 4pyi:
    5. Domain for 4pyj:
    6. Domain for 4pyk:
    7. Domain for 4xuc:
    8. Domain for 4xud:
    9. Domains for 4xue:
      1. 2129316Domain d4xuea_: 4xue A: [271578]
        Other proteins in same PDB: d4xueb2
        automated match to d3bwma_
        complexed with 43j, mg, sam
      2. 2129317Domain d4xueb1: 4xue B:52-265 [271577]
        Other proteins in same PDB: d4xueb2
        automated match to d3bwma_
        complexed with 43j, mg, sam
    10. Domain for 5lsa:
  2. 2129320Norway rat (Rattus norvegicus) [TaxId:10116] [53338] (84 PDB entries)
    1. Domain for 1h1d:
    2. Domain for 1jr4:
    3. Domain for 1vid:
    4. Domain for 3a7d:
    5. Domain for 3nw9:
    6. Domain for 3nwb:
      • 2129323Domain d3nwba_: 3nwb A: [196280]
        automated match to d3u81a_
        protein/RNA complex; complexed with 659, cl, mg, nhe, so4
    7. Domain for 3nwe:
      • 2129327Domain d3nwea_: 3nwe A: [196281]
        automated match to d3u81a_
        protein/RNA complex; complexed with 662, cl, mg, nhe, so4
    8. Domain for 3oe4:
    9. Domain for 3oe5:
    10. Domain for 3ozr:
    11. Domain for 3ozs:
    12. Domain for 3ozt:
    13. Domain for 3r6t:
      • 2129322Domain d3r6ta_: 3r6t A: [184825]
        automated match to d1h1da_
        protein/RNA complex; complexed with cl, dtd, lu1, mg, nhe, so4
    14. Domain for 3s68:
    15. Domain for 3u81:
    16. Domains for 4p7g:
      1. 2129345Domain d4p7ga_: 4p7g A: [257436]
        automated match to d1jr4a_
        complexed with k, po4
      2. 2129346Domain d4p7gb_: 4p7g B: [257438]
        automated match to d1h1da_
        complexed with k, po4
      3. 2129347Domain d4p7gc_: 4p7g C: [257439]
        automated match to d1h1da_
        complexed with k, po4
      4. 2129348Domain d4p7gd_: 4p7g D: [257440]
        automated match to d1h1da_
        complexed with k, po4
    17. Domain for 4p7j:
    18. Domain for 4p7k:
    19. Domain for 4pyl:
    20. Domain for 4pym:
    21. Domain for 4pyn:
    22. Domains for 4pyo:
      1. 2129341Domain d4pyoa_: 4pyo A: [259265]
        automated match to d3u81a_
        complexed with k, mg, sah
      2. 2129342Domain d4pyob_: 4pyo B: [259266]
        automated match to d3u81a_
        complexed with k, mg, sah
    23. Domains for 4pyq:
      1. 2129330Domain d4pyqa_: 4pyq A: [267248]
        automated match to d4p7ka_
        protein/RNA complex; complexed with 2x1, act, cl, na, so4
      2. 2129331Domain d4pyqb_: 4pyq B: [267249]
        automated match to d4p7ka_
        protein/RNA complex; complexed with 2x1, act, cl, na, so4
    24. Domain for 5fhq:
    25. Domain for 5k01:
    26. Domain for 5k03:
    27. Domains for 5k05:
      1. 2278906Domain d5k05a_: 5k05 A: [322207]
        automated match to d4pyoa_
        complexed with 6p5, so4
      2. 2279129Domain d5k05b_: 5k05 B: [322430]
        automated match to d4pyoa_
        complexed with 6p5, so4
    28. Domains for 5k09:
      1. 2278891Domain d5k09c_: 5k09 C: [322192]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      2. 2278898Domain d5k09l_: 5k09 L: [322199]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      3. 2278900Domain d5k09b_: 5k09 B: [322201]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      4. 2278905Domain d5k09m_: 5k09 M: [322206]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      5. 2278911Domain d5k09n_: 5k09 N: [322212]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      6. 2278914Domain d5k09p_: 5k09 P: [322215]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      7. 2278930Domain d5k09a1: 5k09 A:2-217 [322231]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      8. 2278942Domain d5k09f_: 5k09 F: [322243]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      9. 2279002Domain d5k09r1: 5k09 R:2-217 [322303]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      10. 2279004Domain d5k09x_: 5k09 X: [322305]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      11. 2279020Domain d5k09k_: 5k09 K: [322321]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      12. 2279031Domain d5k09g1: 5k09 G:2-217 [322332]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      13. 2279098Domain d5k09t_: 5k09 T: [322399]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      14. 2279105Domain d5k09j_: 5k09 J: [322406]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      15. 2279111Domain d5k09i_: 5k09 I: [322412]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      16. 2279119Domain d5k09u_: 5k09 U: [322420]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      17. 2279120Domain d5k09q_: 5k09 Q: [322421]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      18. 2279121Domain d5k09h_: 5k09 H: [322422]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      19. 2279130Domain d5k09s_: 5k09 S: [322431]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      20. 2279131Domain d5k09e_: 5k09 E: [322432]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      21. 2279133Domain d5k09w_: 5k09 W: [322434]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      22. 2279134Domain d5k09v_: 5k09 V: [322435]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      23. 2279135Domain d5k09d_: 5k09 D: [322436]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
      24. 2279139Domain d5k09o_: 5k09 O: [322440]
        Other proteins in same PDB: d5k09a2, d5k09g2, d5k09r2
        automated match to d4pyna_
        complexed with 6pq, k, po4
    29. Domains for 5k0b:
      1. 2278913Domain d5k0bg_: 5k0b G: [322214]
        Other proteins in same PDB: d5k0bd2
        automated match to d3u81a_
        complexed with 6ps, cl, cxs, edo, k, po4
      2. 2278946Domain d5k0be_: 5k0b E: [322247]
        Other proteins in same PDB: d5k0bd2
        automated match to d3u81a_
        complexed with 6ps, cl, cxs, edo, k, po4
      3. 2278955Domain d5k0ba_: 5k0b A: [322256]
        Other proteins in same PDB: d5k0bd2
        automated match to d3u81a_
        complexed with 6ps, cl, cxs, edo, k, po4
      4. 2278997Domain d5k0bd1: 5k0b D:3-218 [322298]
        Other proteins in same PDB: d5k0bd2
        automated match to d3u81a_
        complexed with 6ps, cl, cxs, edo, k, po4
      5. 2279035Domain d5k0bh_: 5k0b H: [322336]
        Other proteins in same PDB: d5k0bd2
        automated match to d3u81a_
        complexed with 6ps, cl, cxs, edo, k, po4
      6. 2279058Domain d5k0bc_: 5k0b C: [322359]
        Other proteins in same PDB: d5k0bd2
        automated match to d3u81a_
        complexed with 6ps, cl, cxs, edo, k, po4
      7. 2279095Domain d5k0bb_: 5k0b B: [322396]
        Other proteins in same PDB: d5k0bd2
        automated match to d3u81a_
        complexed with 6ps, cl, cxs, edo, k, po4
      8. 2279128Domain d5k0bf_: 5k0b F: [322429]
        Other proteins in same PDB: d5k0bd2
        automated match to d3u81a_
        complexed with 6ps, cl, cxs, edo, k, po4
    30. Domains for 5k0c:
      1. 2278890Domain d5k0cb_: 5k0c B: [322191]
        automated match to d4pyob_
        complexed with 6oz, edo, na, nhe
      2. 2279122Domain d5k0ca_: 5k0c A: [322423]
        automated match to d4pyob_
        complexed with 6oz, edo, na, nhe
    31. Domain for 5k0e:
    32. Domains for 5k0f:
      1. 2278902Domain d5k0fa_: 5k0f A: [322203]
        automated match to d4pyna_
        complexed with 6p1, na, nhe
      2. 2279066Domain d5k0fb_: 5k0f B: [322367]
        automated match to d4pyna_
        complexed with 6p1, na, nhe
    33. Domains for 5k0g:
      1. 2278923Domain d5k0ga_: 5k0g A: [322224]
        automated match to d4pyna_
        complexed with 6pm, na, nhe
      2. 2278928Domain d5k0gb_: 5k0g B: [322229]
        automated match to d4pyna_
        complexed with 6pm, na, nhe
    34. Domains for 5k0j:
      1. 2279021Domain d5k0ja_: 5k0j A: [322322]
        automated match to d4pyna_
        complexed with 6p2, na, nhe
      2. 2279052Domain d5k0jb_: 5k0j B: [322353]
        automated match to d4pyna_
        complexed with 6p2, na, nhe
    35. Domains for 5k0l:
      1. 2278892Domain d5k0ld_: 5k0l D: [322193]
        automated match to d4pyna_
        complexed with 6p2, k, mg, nhe
      2. 2279123Domain d5k0la_: 5k0l A: [322424]
        automated match to d4pyna_
        complexed with 6p2, k, mg, nhe
      3. 2279125Domain d5k0lb_: 5k0l B: [322426]
        automated match to d4pyna_
        complexed with 6p2, k, mg, nhe
      4. 2279132Domain d5k0lc_: 5k0l C: [322433]
        automated match to d4pyna_
        complexed with 6p2, k, mg, nhe
    36. Domains for 5k0n:
      1. 2278922Domain d5k0nb_: 5k0n B: [322223]
        automated match to d4pyna_
        complexed with 6p0, edo, k, mg, nhe
      2. 2278933Domain d5k0nc_: 5k0n C: [322234]
        automated match to d4pyna_
        complexed with 6p0, edo, k, mg, nhe
      3. 2278934Domain d5k0nd_: 5k0n D: [322235]
        automated match to d4pyna_
        complexed with 6p0, edo, k, mg, nhe
      4. 2278943Domain d5k0na_: 5k0n A: [322244]
        automated match to d4pyna_
        complexed with 6p0, edo, k, mg, nhe
    37. Domain for 5lqa:
    38. Domain for 5lqc:
    39. Domains for 5lqj:
      1. 2280145Domain d5lqja_: 5lqj A: [323446]
        automated match to d4pyna_
        complexed with 72n, cl, k, na
      2. 2280149Domain d5lqjc_: 5lqj C: [323450]
        automated match to d4pyna_
        complexed with 72n, cl, k, na
      3. 2280167Domain d5lqjd_: 5lqj D: [323468]
        automated match to d4pyna_
        complexed with 72n, cl, k, na
      4. 2280198Domain d5lqjb_: 5lqj B: [323499]
        automated match to d4pyna_
        complexed with 72n, cl, k, na
    40. Domain for 5lqk:
    41. Domain for 5lqn:
    42. Domain for 5lqr:
    43. Domains for 5lqu:
      1. 2280438Domain d5lqub_: 5lqu B: [323739]
        automated match to d1h1da_
        complexed with 619, btb, cl, mg
      2. 2280465Domain d5lqua_: 5lqu A: [323766]
        automated match to d1h1da_
        complexed with 619, btb, cl, mg
    44. Domains for 5lr6:
      1. 2278711Domain d5lr6c_: 5lr6 C: [322012]
        automated match to d4pyna_
        complexed with 731, cl, nhe
      2. 2278721Domain d5lr6d_: 5lr6 D: [322022]
        automated match to d4pyna_
        complexed with 731, cl, nhe
      3. 2278752Domain d5lr6b_: 5lr6 B: [322053]
        automated match to d4pyna_
        complexed with 731, cl, nhe
      4. 2278786Domain d5lr6a_: 5lr6 A: [322087]
        automated match to d4pyna_
        complexed with 731, cl, nhe
    45. Domains for 5p8w:
      1. 2279001Domain d5p8wb_: 5p8w B: [322302]
        automated match to d4pyna_
        complexed with dtt, fmt, na, o01
      2. 2279008Domain d5p8wc_: 5p8w C: [322309]
        automated match to d4pyna_
        complexed with dtt, fmt, na, o01
      3. 2279070Domain d5p8wa_: 5p8w A: [322371]
        automated match to d4pyna_
        complexed with dtt, fmt, na, o01
    46. Domain for 5p8x:
    47. Domain for 5p8y:
    48. Domain for 5p8z:
    49. Domain for 5p90:
    50. Domain for 5p91:
    51. Domain for 5p92:
    52. Domain for 5p93:
    53. Domain for 5p94:
    54. Domain for 5p95:
    55. Domain for 5p96:
    56. Domain for 5p97:
    57. Domain for 5p98:
    58. Domain for 5p99:
    59. Domain for 5p9a:
    60. Domain for 5p9b:
    61. Domain for 5p9c:
    62. Domain for 5p9d:
    63. Domain for 5p9e:
    64. Domain for 5p9n:
    65. Domain for 5p9o:
    66. Domain for 5p9p:
    67. Domain for 5p9q:
    68. Domains for 5p9r:
      1. 2298576Domain d5p9ra_: 5p9r A: [341877]
        automated match to d4pyna_
        complexed with 7jj, cl, mg, na, sah
      2. 2298577Domain d5p9rb_: 5p9r B: [341878]
        automated match to d4pyna_
        complexed with 7jj, cl, mg, na, sah
    69. Domain for 5p9s:
    70. Domain for 5p9t:
    71. Domain for 5p9u:
    72. Domain for 5p9v:
    73. Domain for 5p9w:
    74. Domain for 5p9x:
    75. Domain for 5p9y:
    76. Domain for 5p9z:
    77. Domain for 5pa0:
    78. Domain for 5pa1:
    79. Domain for 5pa2:
    80. Domain for 5pa3:
    81. Domain for 5pa4:
    82. Domain for 5pa5:
    83. Domain for 5pa6:
    84. Domains for 5pa7:
      1. 2298565Domain d5pa7b_: 5pa7 B: [341866]
        automated match to d4pyna_
        complexed with 7jx, mg, na, sah
      2. 2298595Domain d5pa7a_: 5pa7 A: [341896]
        automated match to d4pyna_
        complexed with 7jx, mg, na, sah

More info for Protein Catechol O-methyltransferase, COMT from c.66.1.1: COMT-like

Timeline for Protein Catechol O-methyltransferase, COMT from c.66.1.1: COMT-like: