SCOP 1.63: Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases

Lineage for Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases

1. Root: SCOP 1.63

2. Class c: Alpha and beta proteins (a/b) [51349] (117 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (23 families)

Families:

1. c.66.1.1: Catechol O-methyltransferase, COMT [53336] (1 protein)

2. c.66.1.2: RNA methyltransferase FtsJ [53339] (1 protein)

3. c.66.1.3: Fibrillarin homologue [53342] (1 protein)

4. c.66.1.4: Hypothetical protein MJ0882 [53345] (1 protein)

5. c.66.1.5: Glycine N-methyltransferase [53348] (1 protein)

6. c.66.1.6: Arginine methyltransferase, HMT1 [53351] (1 protein)
   lacks the last two strands of the common fold replaced with a beta-sandwich oligomerisation subdomain

7. c.66.1.7: Protein-L-isoaspartyl O-methyltransferase [53354] (1 protein)
   topological variant; strand order 3214567; strand 6 is antiparallel to the rest

8. c.66.1.8: Chemotaxis receptor methyltransferase CheR, C-terminal domain [53357] (1 protein)
   contains additional N-terminal all-alpha domain, res. 11-91

9. c.66.1.9: RNA methylases [53360] (3 proteins)

10. c.66.1.10: DNA methylases [53366] (5 proteins)

11. c.66.1.11: Type II DNA methylase [53377] (3 proteins)
    circularly permuted version of the common fold

12. c.66.1.12: Plant O-methyltransferase, C-terminal domain [64111] (3 proteins)

13. c.66.1.13: Probable methyltransferase Rv2118c [64117] (1 protein)
    contains additional N-terminal beta-sandwich domain, res. 1-67

14. c.66.1.14: Hypothetical protein HI0319 (YecO) [69544] (1 protein)

15. c.66.1.15: Phenylethanolamine N-methyltransferase, PNMTase [69547] (1 protein)

16. c.66.1.16: Guanidinoacetate methyltransferase [69550] (1 protein)

17. c.66.1.17: Spermidine synthase [69557] (2 proteins)
    contains additional N-terminal tetramerisation all-beta domain, res. 1-71

18. c.66.1.18: Mycolic acid cyclopropane synthase [69560] (2 proteins)

19. c.66.1.19: Histamine methyltransferase [75261] (1 protein)

20. c.66.1.20: Glucose-inhibited division protein B (GidB) [75264] (1 protein)

21. c.66.1.21: Hypothetical Protein Yjhp [82469] (1 protein)

22. c.66.1.22: Precorrin-6Y methyltransferase (CbiT) [82472] (1 protein)

23. c.66.1.23: MraW-like putative methyltransferases [82475] (1 protein)

More info for Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases

Timeline for Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases:

• Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases first appeared (with stable ids) in SCOP 1.55
  
• Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases appears in SCOP 1.61
  
• Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases appears in SCOP 1.65
  
• Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases appears in the current release, SCOPe 2.08