Lineage for Family c.61.1.1: Phosphoribosyltransferases (PRTases)

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 838986Fold c.61: PRTase-like [53270] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest
  4. 838987Superfamily c.61.1: PRTase-like [53271] (2 families) (S)
  5. 838988Family c.61.1.1: Phosphoribosyltransferases (PRTases) [53272] (15 proteins)

Proteins:

  1. 838989Adenine PRTase [53288] (5 species)
    1. 838990Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [69541] (2 PDB entries)
    2. 838994Species Giardia lamblia [TaxId:5741] [82455] (2 PDB entries)
    3. 838997Species Human (Homo sapiens) [TaxId:9606] [102536] (4 PDB entries)
    4. 839005Species Leishmania donovani [TaxId:5661] [53289] (4 PDB entries)
    5. 839010Species Leishmania tarentolae [TaxId:5689] [102535] (1 PDB entry)
  2. 839012Glutamine PRPP amidotransferase, C-terminal domain [53278] (2 species)
    1. 839013Species Bacillus subtilis [TaxId:1423] [53279] (2 PDB entries)
    2. 839022Species Escherichia coli [TaxId:562] [53280] (5 PDB entries)
  3. 839037Guanine PRTase [53281] (1 species)
  4. 839043Hypoxanthine PRTase [53286] (3 species)
    1. 839044Species Escherichia coli [TaxId:562] [75255] (3 PDB entries)
    2. 839051Species Salmonella typhimurium [TaxId:90371] [89728] (1 PDB entry)
    3. 839054Species Trypanosoma cruzi [TaxId:5693] [53287] (9 PDB entries)
      Uniprot Q27796
  5. 839077Hypoxanthine-guanine PRTase (HGPRTase) [53283] (3 species)
    1. 839078Species Human (Homo sapiens) [TaxId:9606] [53284] (4 PDB entries)
    2. 839091Species Plasmodium falciparum [TaxId:5833] [53285] (1 PDB entry)
    3. 839096Species Thermoanaerobacter tengcongensis [TaxId:119072] [117671] (1 PDB entry)
      Uniprot Q8R7L0
  6. 839099Hypoxanthine-guanine-xanthine PRTase [53275] (3 species)
    1. 839100Species Leishmania tarentolae [TaxId:5689] [110658] (1 PDB entry)
      Uniprot Q9NJI5
    2. 839103Species Toxoplasma gondii [TaxId:5811] [53277] (5 PDB entries)
    3. 839120Species Tritrichomonas foetus [TaxId:5724] [53276] (1 PDB entry)
  7. 839123Orotate PRTase [53290] (3 species)
    1. 839124Species Escherichia coli [TaxId:562] [53292] (1 PDB entry)
    2. 839127Species Salmonella typhimurium [TaxId:90371] [53291] (3 PDB entries)
    3. 839132Species Streptococcus pyogenes [TaxId:1314] [142553] (1 PDB entry)
      Uniprot Q9A076 1-208
  8. 839135Pprobable purine phosphoribosyltransferase PH0095 [142560] (1 species)
  9. 839149Pur operon repressor (PurR), C-terminal domain [102539] (1 species)
  10. 839159Putative phosphoribosyltransferase TT1426 (TTHA1462) [117673] (1 species)
  11. 839162Putative phosphoribosyltransferase TTHA1613 [142558] (1 species)
    putative APRTase in UniProt
  12. 839169Pyrimidine operon regulator PyrR [109612] (4 species)
    bifunctional protein; contains the uracil PRTase and Pyr RNA-binding activities
    1. 839170Species Bacillus caldolyticus [TaxId:1394] [110659] (4 PDB entries)
      Uniprot P41007
    2. 839181Species Bacillus subtilis [TaxId:1423] [53294] (2 PDB entries)
    3. 839185Species Mycobacterium tuberculosis [TaxId:1773] [117672] (1 PDB entry)
      Uniprot P71807
    4. 839188Species Thermus thermophilus [TaxId:274] [102537] (1 PDB entry)
      TT1027
  13. 839193Uracil PRTase, Upp [53293] (5 species)
    1. 839194Species Bacillus caldolyticus [TaxId:1394] [75256] (1 PDB entry)
    2. 839197Species Sulfolobus solfataricus [TaxId:2287] [142555] (3 PDB entries)
      Uniprot Q980Q4 2-216
    3. 839218Species Thermotoga maritima [TaxId:2336] [102538] (1 PDB entry)
      TM0721
    4. 839223Species Thermus thermophilus [TaxId:274] [142554] (1 PDB entry)
      Uniprot Q72J35 1-208
    5. 839228Species Toxoplasma gondii [TaxId:5811] [53295] (6 PDB entries)
  14. 839253Xanthine phosphoribosyltransferase [142556] (1 species)
  15. 839261Xanthine-guanine PRTase (XPRTase) [53273] (2 species)
    1. 839262Species Escherichia coli [TaxId:562] [53274] (5 PDB entries)
    2. 839279Species Thermoanaerobacter tengcongensis [TaxId:119072] [142552] (1 PDB entry)
      Uniprot Q8R7L0 3-180

More info for Family c.61.1.1: Phosphoribosyltransferases (PRTases)

Timeline for Family c.61.1.1: Phosphoribosyltransferases (PRTases):