Lineage for Family c.61.1.1: Phosphoribosyltransferases (PRTases)

  1. Root: SCOP 1.69
  2. 473232Class c: Alpha and beta proteins (a/b) [51349] (136 folds)
  3. 489867Fold c.61: PRTase-like [53270] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest
  4. 489868Superfamily c.61.1: PRTase-like [53271] (2 families) (S)
  5. 489869Family c.61.1.1: Phosphoribosyltransferases (PRTases) [53272] (11 proteins)

Proteins:

  1. 489870Adenine PRTase [53288] (5 species)
    1. 489871Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [69541] (2 PDB entries)
    2. 489875Species Giardia lamblia [TaxId:184922] [82455] (2 PDB entries)
    3. 489878Species Human (Homo sapiens) [TaxId:9606] [102536] (1 PDB entry)
    4. 489880Species Leishmania donovani [TaxId:5661] [53289] (4 PDB entries)
    5. 489885Species Leishmania tarentolae [TaxId:5689] [102535] (1 PDB entry)
  2. 489887Glutamine PRPP amidotransferase, C-terminal domain [53278] (2 species)
    1. 489888Species Bacillus subtilis [TaxId:1423] [53279] (2 PDB entries)
    2. 489897Species Escherichia coli [TaxId:562] [53280] (5 PDB entries)
  3. 489912Guanine PRTase [53281] (1 species)
  4. 489918Hypoxanthine PRTase [53286] (3 species)
    1. 489919Species Escherichia coli [TaxId:562] [75255] (3 PDB entries)
    2. 489926Species Salmonella typhimurium [TaxId:90371] [89728] (1 PDB entry)
    3. 489929Species Trypanosoma cruzi [TaxId:5693] [53287] (9 PDB entries)
  5. 489952Hypoxanthine-guanine PRTase (HGPRTase) [53283] (2 species)
    1. 489953Species Human (Homo sapiens) [TaxId:9606] [53284] (3 PDB entries)
    2. 489962Species Plasmodium falciparum [53285] (1 PDB entry)
  6. 489967Hypoxanthine-guanine-xanthine PRTase [53275] (3 species)
    1. 489968Species Leishmania tarentolae [TaxId:5689] [110658] (1 PDB entry)
    2. 489971Species Toxoplasma gondii [TaxId:5811] [53277] (5 PDB entries)
    3. 489988Species Tritrichomonas foetus [TaxId:5724] [53276] (1 PDB entry)
  7. 489991Orotate PRTase [53290] (2 species)
    1. 489992Species Escherichia coli [TaxId:562] [53292] (1 PDB entry)
    2. 489995Species Salmonella typhimurium [TaxId:90371] [53291] (3 PDB entries)
  8. 490000Pur operon repressor (PurR), C-terminal domain [102539] (1 species)
  9. 490010Pyrimidine operon regulator PyrR [109612] (3 species)
    bifunctional protein; contains the uracil PRTase and Pyr RNA-binding activities
    1. 490011Species Bacillus caldolyticus [TaxId:1394] [110659] (1 PDB entry)
    2. 490016Species Bacillus subtilis [TaxId:1423] [53294] (2 PDB entries)
    3. 490020Species Thermus thermophilus [TaxId:274] [102537] (1 PDB entry)
      TT1027
  10. 490025Uracil PRTase, Upp [53293] (3 species)
    1. 490026Species Bacillus caldolyticus [TaxId:1394] [75256] (1 PDB entry)
    2. 490029Species Thermotoga maritima [TaxId:243274] [102538] (1 PDB entry)
      TM0721
    3. 490034Species Toxoplasma gondii [TaxId:5811] [53295] (6 PDB entries)
  11. 490059Xanthine-guanine PRTase (XPRTase) [53273] (1 species)

More info for Family c.61.1.1: Phosphoribosyltransferases (PRTases)

Timeline for Family c.61.1.1: Phosphoribosyltransferases (PRTases):