Lineage for Protein: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain

  1. Root: SCOP 1.65
  2. 305035Class c: Alpha and beta proteins (a/b) [51349] (121 folds)
  3. 317891Fold c.60: Phosphoglycerate mutase-like [53253] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 324156; strand 5 is antiparallel to the rest
  4. 317892Superfamily c.60.1: Phosphoglycerate mutase-like [53254] (4 families) (S)
  5. 317966Family c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain [53267] (1 protein)
  6. 317967Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain [53268] (2 species)
    bifunctional enzyme

Species:

  1. 317968Human (Homo sapiens) [TaxId:9606] [82454] (1 PDB entry)
  2. 317971Rat (Rattus norvegicus) [TaxId:10116] [53269] (8 PDB entries)
    1. Domain for 1bif:
    2. Domains for 1c7z:
      1. 317982Domain d1c7za_: 1c7z A: [83160]
      2. 317983Domain d1c7zb_: 1c7z B: [83161]
        complexed with g3p, po4
    3. Domains for 1c80:
      1. 317975Domain d1c80a_: 1c80 A: [83162]
      2. 317976Domain d1c80b_: 1c80 B: [83163]
        complexed with gtp, po4
    4. Domain for 1c81:
    5. Domains for 1fbt:
      1. 317973Domain d1fbta_: 1fbt A: [34004]
      2. 317974Domain d1fbtb_: 1fbt B: [34005]
        complexed with po4; mutant
    6. Domains for 1tip:
      1. 317977Domain d1tipa_: 1tip A: [34006]
      2. 317978Domain d1tipb_: 1tip B: [34007]
        complexed with f6p, h2p; mutant
    7. Domains for 2bif:
      1. 317980Domain d2bifa2: 2bif A:250-468 [34009]
        Other proteins in same PDB: d2bifa1, d2bifb1
      2. 317981Domain d2bifb2: 2bif B:250-468 [34010]
        Other proteins in same PDB: d2bifa1, d2bifb1
        complexed with app, bog, f6p, mg, po4, sux; mutant
    8. Domain for 3bif:

More info for Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain from c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain

Timeline for Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain from c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain:

  • Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain from c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain first appeared (with stable ids) in SCOP 1.55
  • Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain from c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain appears in SCOP 1.63
  • Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain from c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain appears in SCOP 1.67
  • Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain from c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain appears in the current release, SCOPe 2.08