Lineage for Protein: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain

  1. Root: SCOP 1.63
  2. 235644Class c: Alpha and beta proteins (a/b) [51349] (117 folds)
  3. 247122Fold c.60: Phosphoglycerate mutase-like [53253] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 324156; strand 5 is antiparallel to the rest
  4. 247123Superfamily c.60.1: Phosphoglycerate mutase-like [53254] (4 families) (S)
  5. 247197Family c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain [53267] (1 protein)
  6. 247198Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain [53268] (2 species)
    bifunctional enzyme

Species:

  1. 247199Human (Homo sapiens) [TaxId:9606] [82454] (1 PDB entry)
  2. 247202Rat (Rattus norvegicus) [TaxId:10116] [53269] (5 PDB entries)
    1. Domain for 1bif:
    2. Domains for 1fbt:
      1. 247204Domain d1fbta_: 1fbt A: [34004]
      2. 247205Domain d1fbtb_: 1fbt B: [34005]
        complexed with po4; mutant
    3. Domains for 1tip:
      1. 247206Domain d1tipa_: 1tip A: [34006]
      2. 247207Domain d1tipb_: 1tip B: [34007]
        complexed with f6p, h2p; mutant
    4. Domains for 2bif:
      1. 247209Domain d2bifa2: 2bif A:250-468 [34009]
        Other proteins in same PDB: d2bifa1, d2bifb1
      2. 247210Domain d2bifb2: 2bif B:250-468 [34010]
        Other proteins in same PDB: d2bifa1, d2bifb1
        complexed with app, bog, f6p, mg, po4, sux; mutant
    5. Domain for 3bif:

More info for Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain from c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain

Timeline for Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain from c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain:

  • Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain from c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain first appeared (with stable ids) in SCOP 1.55
  • Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain from c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain appears in SCOP 1.61
  • Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain from c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain appears in SCOP 1.65
  • Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain from c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain appears in the current release, SCOPe 2.08