Lineage for Protein: Tetrahydrofolate dehydrogenase/cyclohydrolase

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2498096Fold c.58: Aminoacid dehydrogenase-like, N-terminal domain [53222] (1 superfamily)
    core: 3 layers: a/b/a; parallel beta-sheet of 4 strands; 2134
  4. 2498097Superfamily c.58.1: Aminoacid dehydrogenase-like, N-terminal domain [53223] (6 families) (S)
  5. 2498288Family c.58.1.2: Tetrahydrofolate dehydrogenase/cyclohydrolase [53235] (2 proteins)
    automatically mapped to Pfam PF00763
  6. 2498289Protein Tetrahydrofolate dehydrogenase/cyclohydrolase [53236] (3 species)
    the two-domain organization is similar to that of aminoacid dehydrogenases, but both domains are truncated

Species:

  1. 2498290Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [53239] (2 PDB entries)
    1. Domain for 1edz:
    2. Domain for 1ee9:
  2. 2498293Escherichia coli [TaxId:562] [53238] (1 PDB entry)
  3. 2498295Human (Homo sapiens) [TaxId:9606] [53237] (7 PDB entries)
    1. Domains for 1a4i:
      1. 2498296Domain d1a4ia2: 1a4i A:2-126 [33926]
        Other proteins in same PDB: d1a4ia1, d1a4ib1
        complexed with ndp
      2. 2498297Domain d1a4ib2: 1a4i B:2-126 [33927]
        Other proteins in same PDB: d1a4ia1, d1a4ib1
        complexed with ndp
    2. Domains for 1dia:
      1. 2498300Domain d1diaa2: 1dia A:2-126 [33928]
        Other proteins in same PDB: d1diaa1, d1diab1
        complexed with l24, nap
      2. 2498301Domain d1diab2: 1dia B:1002-1126 [33929]
        Other proteins in same PDB: d1diaa1, d1diab1
        complexed with l24, nap
    3. Domains for 1dib:
      1. 2498302Domain d1diba2: 1dib A:2-126 [33932]
        Other proteins in same PDB: d1diba1, d1dibb1
        complexed with l34, nap
      2. 2498303Domain d1dibb2: 1dib B:1002-1126 [33933]
        Other proteins in same PDB: d1diba1, d1dibb1
        complexed with l34, nap
    4. Domains for 1dig:
      1. 2498298Domain d1diga2: 1dig A:2-126 [33930]
        Other proteins in same PDB: d1diga1, d1digb1
        complexed with act, l37, nap
      2. 2498299Domain d1digb2: 1dig B:1002-1126 [33931]
        Other proteins in same PDB: d1diga1, d1digb1
        complexed with act, l37, nap
    5. Domains for 6ecp:
      1. 2498304Domain d6ecpa1: 6ecp A:2-126 [366814]
        Other proteins in same PDB: d6ecpa2, d6ecpb2
        automated match to d1diga2
        complexed with 21v, nap
      2. 2498305Domain d6ecpb1: 6ecp B:2-126 [366761]
        Other proteins in same PDB: d6ecpa2, d6ecpb2
        automated match to d1diga2
        complexed with 21v, nap
    6. Domain for 6ecq:
    7. Domain for 6ecr:

More info for Protein Tetrahydrofolate dehydrogenase/cyclohydrolase from c.58.1.2: Tetrahydrofolate dehydrogenase/cyclohydrolase

Timeline for Protein Tetrahydrofolate dehydrogenase/cyclohydrolase from c.58.1.2: Tetrahydrofolate dehydrogenase/cyclohydrolase: