Lineage for Protein: Carboxypeptidase A

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 702659Fold c.56: Phosphorylase/hydrolase-like [53162] (7 superfamilies)
    core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
  4. 703083Superfamily c.56.5: Zn-dependent exopeptidases [53187] (8 families) (S)
    core: mixed beta-sheet of 8 strands, order 12435867; strands 2, 6 & 7 are antiparallel to the rest
  5. 703084Family c.56.5.1: Pancreatic carboxypeptidases [53188] (4 proteins)
  6. 703085Protein Carboxypeptidase A [53189] (4 species)

Species:

  1. 703086Cotton bollworm (Helicoverpa armigera) [TaxId:29058] [75247] (1 PDB entry)
  2. 703088Cow (Bos taurus) [TaxId:9913] [53190] (27 PDB entries)
    1. Domain for 1arl:
    2. Domain for 1arm:
    3. Domains for 1bav:
      1. 703094Domain d1bava_: 1bav A: [33806]
      2. 703095Domain d1bavb_: 1bav B: [33807]
      3. 703096Domain d1bavc_: 1bav C: [33808]
      4. 703097Domain d1bavd_: 1bav D: [33809]
        complexed with bip, zn
    4. Domain for 1cbx:
    5. Domain for 1cps:
    6. Domain for 1cpx:
      • 703126Domain d1cpxa_: 1cpx A: [33814]
        truncated beta form with two zinc ions in the active site
        complexed with oh, zn
    7. Domain for 1ee3:
    8. Domain for 1ell:
    9. Domain for 1elm:
    10. Domain for 1f57:
    11. Domain for 1hdq:
    12. Domains for 1hdu:
      1. 703102Domain d1hdua_: 1hdu A: [65810]
      2. 703103Domain d1hdub_: 1hdu B: [65811]
      3. 703104Domain d1hdud_: 1hdu D: [65812]
      4. 703105Domain d1hdue_: 1hdu E: [65813]
        complexed with ing, zn
    13. Domains for 1hee:
      1. 703106Domain d1heea_: 1hee A: [65814]
      2. 703107Domain d1heeb_: 1hee B: [65815]
      3. 703108Domain d1heed_: 1hee D: [65816]
      4. 703109Domain d1heee_: 1hee E: [65817]
        complexed with lhy, zn
    14. Domain for 1iy7:
    15. Domain for 1m4l:
    16. Domain for 1pyt:
    17. Domain for 1yme:
    18. Domain for 1zlh:
    19. Domains for 2abz:
      1. 703117Domain d2abza1: 2abz A:4-305 [126537]
        automatically matched to d1arl__
        complexed with zn; mutant
      2. 703118Domain d2abzb1: 2abz B:3-305 [126538]
        automatically matched to d1arl__
        complexed with zn; mutant
    20. Domain for 2ctb:
    21. Domain for 2ctc:
    22. Domain for 3cpa:
    23. Domains for 4cpa:
      1. 703124Domain d4cpaa_: 4cpa A: [33821]
        Other proteins in same PDB: d4cpai_, d4cpaj_
        complexed with zn
      2. 703125Domain d4cpab_: 4cpa B: [118682]
        Other proteins in same PDB: d4cpai_, d4cpaj_
        duplicate of 4CPA
        complexed with zn
    24. Domain for 5cpa:
    25. Domain for 6cpa:
    26. Domain for 7cpa:
    27. Domain for 8cpa:
  3. 703127Human (Homo sapiens) [TaxId:9606] [53192] (5 PDB entries)
    1. Domain for 1aye:
    2. Domain for 1dtd:
    3. Domains for 2bo9:
      1. 703128Domain d2bo9a1: 2bo9 A:4-307 [128897]
        Other proteins in same PDB: d2bo9b1, d2bo9b2, d2bo9d1, d2bo9d2
        Procarboxypeptidase A4
        complexed with acn, mpd, nag, val, zn
      2. 703129Domain d2bo9c1: 2bo9 C:4-307 [128900]
        Other proteins in same PDB: d2bo9b1, d2bo9b2, d2bo9d1, d2bo9d2
        automatically matched to 2BO9 A:4-307
        complexed with acn, mpd, nag, val, zn
    4. Domains for 2boa:
      1. 703133Domain d2boaa1: 2boa A:1001-1309 [128903]
        Other proteins in same PDB: d2boaa2, d2boab2
        Procarboxypeptidase A4
        complexed with gol, nag, zn
      2. 703134Domain d2boab1: 2boa B:1001-1309 [128905]
        Other proteins in same PDB: d2boaa2, d2boab2
        automatically matched to 2BOA A:1001-1309
        complexed with gol, nag, zn
    5. Domain for 2pcu:
      • 703130Domain d2pcua1: 2pcu A:5-307 [139655]
        automatically matched to 2BO9 A:4-307
        complexed with asp, gol, nag, scn, zn
  4. 703135Pig (Sus scrofa) [TaxId:9823] [53191] (1 PDB entry)

More info for Protein Carboxypeptidase A from c.56.5.1: Pancreatic carboxypeptidases

Timeline for Protein Carboxypeptidase A from c.56.5.1: Pancreatic carboxypeptidases: