SCOPe 2.08: Family c.56.5.1: Pancreatic carboxypeptidases

Lineage for Family c.56.5.1: Pancreatic carboxypeptidases

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
   core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops

4. Superfamily c.56.5: Zn-dependent exopeptidases [53187] (10 families)
   core: mixed beta-sheet of 8 strands, order 12435867; strands 2, 6 & 7 are antiparallel to the rest

5. Family c.56.5.1: Pancreatic carboxypeptidases [53188] (5 proteins)

Proteins:

1. Carboxypeptidase A [53189] (4 species)

   1. Species Cotton bollworm (Helicoverpa armigera) [TaxId:29058] [75247] (1 PDB entry)

   2. Species Cow (Bos taurus) [TaxId:9913] [53190] (34 PDB entries)

   3. Species Human (Homo sapiens) [TaxId:9606] [53192] (6 PDB entries)

   4. Species Pig (Sus scrofa) [TaxId:9823] [53191] (1 PDB entry)

2. Carboxypeptidase B [53193] (4 species)

   1. Species Corn earworm (Helicoverpa zea) [TaxId:7113] [142511] (1 PDB entry)
      Uniprot Q3T905 117-428

   2. Species Cow (Bos taurus) [TaxId:9913] [53195] (1 PDB entry)

   3. Species Human (Homo sapiens) [TaxId:9606] [75248] (2 PDB entries)

   4. Species Pig (Sus scrofa) [TaxId:9823] [53194] (18 PDB entries)

3. Carboxypeptidase D, catalytic domain [53196] (1 species)

   • Species Crested duck (Lophonetta specularioides) [TaxId:8836] [53197] (2 PDB entries)

4. Carboxypeptidase M, catalytic domain [102504] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [102505] (1 PDB entry)

5. automated matches [190397] (2 species)
   not a true protein

   1. Species Human (Homo sapiens) [TaxId:9606] [188484] (6 PDB entries)

   2. Species Pig (Sus scrofa) [TaxId:9823] [187266] (20 PDB entries)

More info for Family c.56.5.1: Pancreatic carboxypeptidases

Timeline for Family c.56.5.1: Pancreatic carboxypeptidases:

• Family c.56.5.1: Pancreatic carboxypeptidases first appeared (with stable ids) in SCOP 1.55
  
• Family c.56.5.1: Pancreatic carboxypeptidases appears in SCOPe 2.07