SCOPe 2.08: Protein: 5'-deoxy-5'-methylthioadenosine phosphorylase

Lineage for Protein: 5'-deoxy-5'-methylthioadenosine phosphorylase

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops

Superfamily c.56.2: Purine and uridine phosphorylases [53167] (2 families)

complex architecture; contains mixed beta-sheet of 8 strands, order 23415867, strands 3, 6 & 7 are antiparallel to the rest; and barrel, closed; n=5, S=8

Family c.56.2.1: Purine and uridine phosphorylases [53168] (7 proteins)
Protein 5'-deoxy-5'-methylthioadenosine phosphorylase [53174] (3 species)

Species:

Human (Homo sapiens) [TaxId:9606] [53175] (17 PDB entries)
Uniprot Q13126
1. Domain for 1cb0:
  - Domain d1cb0a_: 1cb0 A: [33790]
    complexed with ade
2. Domain for 1cg6:
  - Domain d1cg6a_: 1cg6 A: [33791]
    complexed with mta, so4
3. Domain for 1k27:
  - Domain d1k27a_: 1k27 A: [90926]
    complexed with mtm, po4
4. Domain for 1sd1:
  - Domain d1sd1a_: 1sd1 A: [105426]
    complexed with fmc
5. Domain for 1sd2:
  - Domain d1sd2a_: 1sd2 A: [105427]
    complexed with mth, so4
6. Domain for 3ozc:
  - Domain d3ozca_: 3ozc A: [183410]
    automated match to d1cb0a_
    complexed with 4ct, po4
7. Domains for 3ozd:
  1. Domain d3ozda_: 3ozd A: [183411]
    automated match to d1cb0a_
    complexed with 4ct
  2. Domain d3ozdb_: 3ozd B: [183412]
    automated match to d1cb0a_
    complexed with 4ct
8. Domains for 3oze:
  1. Domain d3ozea_: 3oze A: [183413]
    automated match to d1cb0a_
    complexed with po4
  2. Domain d3ozeb_: 3oze B: [183414]
    automated match to d1cb0a_
    complexed with po4
  3. Domain d3ozec_: 3oze C: [183415]
    automated match to d1cb0a_
    complexed with po4
  4. Domain d3ozed_: 3oze D: [183416]
    automated match to d1cb0a_
    complexed with po4
  5. Domain d3ozee_: 3oze E: [183417]
    automated match to d1cb0a_
    complexed with po4
  6. Domain d3ozef_: 3oze F: [183418]
    automated match to d1cb0a_
    complexed with po4
9. Domain for 5eub:
  - Domain d5euba_: 5eub A: [327308]
    automated match to d1cb0a_
    complexed with 5s7, cl, gol, so4
10. Domains for 5tc5:
  1. Domain d5tc5b_: 5tc5 B: [340127]
    automated match to d1cb0a_
    complexed with big, cl
  2. Domain d5tc5c_: 5tc5 C: [340134]
    automated match to d1cb0a_
    complexed with big, cl
11. Domain for 5tc6:
  - Domain d5tc6a_: 5tc6 A: [340054]
    automated match to d1cb0a_
    complexed with 7a6, cl, gol, na, po4
12. Domain for 5tc7:
  - Domain d5tc7a_: 5tc7 A: [340056]
    automated match to d1cb0a_
    complexed with cl, mth, po4
13. Domain for 5tc8:
  - Domain d5tc8a_: 5tc8 A: [340076]
    automated match to d1cb0a_
    complexed with 2pe, cl, mg, peg, po4, tdi
14. Domain for 6dyz:
  - Domain d6dyza_: 6dyz A: [366409]
    automated match to d1cb0a_
    complexed with cl, edo, os2, po4
15. Domain for 6dz0:
  - Domain d6dz0a_: 6dz0 A: [366411]
    automated match to d1cb0a_
    complexed with cl, edo, os3, po4
16. Domains for 6dz2:
  1. Domain d6dz2a_: 6dz2 A: [366412]
    automated match to d1cb0a_
    complexed with acy, cl, edo, os5
  2. Domain d6dz2b_: 6dz2 B: [366390]
    automated match to d1cb0a_
    complexed with acy, cl, edo, os5
  3. Domain d6dz2c_: 6dz2 C: [366381]
    automated match to d1cb0a_
    complexed with acy, cl, edo, os5
17. Domains for 6dz3:
  1. Domain d6dz3a_: 6dz3 A: [366387]
    automated match to d1cb0a_
    complexed with acy, cl, edo, os6
  2. Domain d6dz3b_: 6dz3 B: [366395]
    automated match to d1cb0a_
    complexed with acy, cl, edo, os6
  3. Domain d6dz3c_: 6dz3 C: [366392]
    automated match to d1cb0a_
    complexed with acy, cl, edo, os6
Sulfolobus solfataricus [TaxId:2287] [69536] (9 PDB entries)
1. Domains for 1jds:
  1. Domain d1jdsa_: 1jds A: [66560]
    complexed with po4, trs
  2. Domain d1jdsb_: 1jds B: [66561]
    complexed with po4, trs
  3. Domain d1jdsc_: 1jds C: [66562]
    complexed with po4, trs
  4. Domain d1jdsd_: 1jds D: [66563]
    complexed with po4, trs
  5. Domain d1jdse_: 1jds E: [66564]
    complexed with po4, trs
  6. Domain d1jdsf_: 1jds F: [66565]
    complexed with po4, trs
2. Domains for 1jdt:
  1. Domain d1jdta_: 1jdt A: [66566]
    complexed with mta, so4
  2. Domain d1jdtb_: 1jdt B: [66567]
    complexed with mta, so4
  3. Domain d1jdtc_: 1jdt C: [66568]
    complexed with mta, so4
3. Domains for 1jdu:
  1. Domain d1jdua_: 1jdu A: [66569]
  2. Domain d1jdub_: 1jdu B: [66570]
  3. Domain d1jduc_: 1jdu C: [66571]
4. Domains for 1jdv:
  1. Domain d1jdva_: 1jdv A: [66572]
    complexed with adn, so4
  2. Domain d1jdvb_: 1jdv B: [66573]
    complexed with adn, so4
  3. Domain d1jdvc_: 1jdv C: [66574]
    complexed with adn, so4
  4. Domain d1jdvd_: 1jdv D: [66575]
    complexed with adn, so4
  5. Domain d1jdve_: 1jdv E: [66576]
    complexed with adn, so4
  6. Domain d1jdvf_: 1jdv F: [66577]
    complexed with adn, so4
5. Domains for 1jdz:
  1. Domain d1jdza_: 1jdz A: [66578]
    complexed with fmb, so4
  2. Domain d1jdzb_: 1jdz B: [66579]
    complexed with fmb, so4
  3. Domain d1jdzc_: 1jdz C: [66580]
    complexed with fmb, so4
6. Domains for 1je0:
  1. Domain d1je0a_: 1je0 A: [66581]
    complexed with po4, trs
  2. Domain d1je0b_: 1je0 B: [66582]
    complexed with po4, trs
  3. Domain d1je0c_: 1je0 C: [66583]
    complexed with po4, trs
7. Domains for 1je1:
  1. Domain d1je1a_: 1je1 A: [66584]
    complexed with gmp, so4
  2. Domain d1je1b_: 1je1 B: [66585]
    complexed with gmp, so4
  3. Domain d1je1c_: 1je1 C: [66586]
    complexed with gmp, so4
  4. Domain d1je1d_: 1je1 D: [66587]
    complexed with gmp, so4
  5. Domain d1je1e_: 1je1 E: [66588]
    complexed with gmp, so4
  6. Domain d1je1f_: 1je1 F: [66589]
    complexed with gmp, so4
8. Domains for 1jp7:
  1. Domain d1jp7a_: 1jp7 A: [67006]
    complexed with so4
  2. Domain d1jp7b_: 1jp7 B: [67007]
    complexed with so4
  3. Domain d1jp7c_: 1jp7 C: [67008]
    complexed with so4
9. Domains for 1jpv:
  1. Domain d1jpva_: 1jpv A: [67056]
    complexed with so4
  2. Domain d1jpvb_: 1jpv B: [67057]
    complexed with so4
  3. Domain d1jpvc_: 1jpv C: [67058]
    complexed with so4
Sulfolobus tokodaii [TaxId:111955] [117657] (1 PDB entry)
Uniprot Q975C3
- Domains for 1v4n:
  1. Domain d1v4na1: 1v4n A:7-271 [113530]
    Other proteins in same PDB: d1v4na2, d1v4nb2
    structural genomics target
  2. Domain d1v4nb1: 1v4n B:4-271 [113531]
    Other proteins in same PDB: d1v4na2, d1v4nb2
    structural genomics target
  3. Domain d1v4nc_: 1v4n C: [113532]
    Other proteins in same PDB: d1v4na2, d1v4nb2
    structural genomics target

More info for Protein 5'-deoxy-5'-methylthioadenosine phosphorylase from c.56.2.1: Purine and uridine phosphorylases

Timeline for Protein 5'-deoxy-5'-methylthioadenosine phosphorylase from c.56.2.1: Purine and uridine phosphorylases:

Protein 5'-deoxy-5'-methylthioadenosine phosphorylase from c.56.2.1: Purine and uridine phosphorylases first appeared (with stable ids) in SCOP 1.55
Protein 5'-deoxy-5'-methylthioadenosine phosphorylase from c.56.2.1: Purine and uridine phosphorylases appears in SCOPe 2.07