Lineage for Family c.56.2.1: Purine and uridine phosphorylases

  1. Root: SCOPe 2.05
  2. 1815291Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1860688Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
    core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
  4. 1860705Superfamily c.56.2: Purine and uridine phosphorylases [53167] (2 families) (S)
    complex architecture; contains mixed beta-sheet of 8 strands, order 23415867, strands 3, 6 & 7 are antiparallel to the rest; and barrel, closed; n=5, S=8
  5. 1860706Family c.56.2.1: Purine and uridine phosphorylases [53168] (7 proteins)

Proteins:

  1. 18607075'-deoxy-5'-methylthioadenosine phosphorylase [53174] (3 species)
    1. 1860708Species Human (Homo sapiens) [TaxId:9606] [53175] (8 PDB entries)
      Uniprot Q13126
    2. 1860723Species Sulfolobus solfataricus [TaxId:2287] [69536] (9 PDB entries)
    3. 1860760Species Sulfolobus tokodaii [TaxId:111955] [117657] (1 PDB entry)
      Uniprot Q975C3
  2. 18607645'-Methylthioadenosine/S-Adenosylhomocysteine nucleosidase [82448] (3 species)
    1. 1860765Species Escherichia coli [TaxId:562] [82449] (8 PDB entries)
    2. 1860781Species Neisseria meningitidis [TaxId:491] [188964] (1 PDB entry)
    3. 1860784Species Staphylococcus aureus [TaxId:1280] [188463] (1 PDB entry)
  3. 1860786AMP nucleosidase [110645] (2 species)
    contains extra N-terminal oligomerisation (sub)domain (8-153)
    1. 1860787Species Bacteroides thetaiotaomicron [TaxId:818] [117658] (1 PDB entry)
      Uniprot Q7MVU1
    2. 1860791Species Escherichia coli [TaxId:562] [110646] (4 PDB entries)
      Uniprot P15272
  4. 1860816Purine nucleoside phosphorylase, PNP [53169] (12 species)
    1. 1860817Species Anthrax bacillus (Bacillus anthracis) [TaxId:1392] [117655] (1 PDB entry)
      Uniprot Q81T09
    2. 1860824Species Bacillus cereus [TaxId:1396] [195935] (5 PDB entries)
    3. 1860830Species Bacillus cereus [TaxId:269801] [186942] (1 PDB entry)
    4. 1860833Species Cellulomonas sp. [TaxId:40001] [53173] (2 PDB entries)
    5. 1860840Species Cow (Bos taurus) [TaxId:9913] [53171] (20 PDB entries)
      Uniprot P55859
    6. 1860873Species Escherichia coli [TaxId:562] [53172] (27 PDB entries)
    7. 1860994Species Human (Homo sapiens) [TaxId:9606] [53170] (29 PDB entries)
      Uniprot P00491
    8. 1861033Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [226822] (1 PDB entry)
    9. 1861040Species Mycobacterium tuberculosis [TaxId:1773] [64098] (3 PDB entries)
    10. 1861050Species Thermotoga maritima [TaxId:2336] [117654] (1 PDB entry)
      Uniprot Q9X1T2
    11. 1861054Species Thermus thermophilus [TaxId:274] [89721] (4 PDB entries)
    12. 1861079Species Vibrio cholerae [TaxId:666] [102499] (2 PDB entries)
  5. 1861092Putative uridine phosphorylase [102500] (1 species)
  6. 1861107Uridine phosphorylase [53176] (5 species)
    1. 1861108Species Escherichia coli [TaxId:562] [53177] (15 PDB entries)
    2. 1861209Species Salmonella typhimurium [TaxId:90371] [117656] (24 PDB entries)
      Uniprot P0A1F6
    3. 1861337Species Vibrio cholerae [TaxId:243277] [224899] (8 PDB entries)
    4. 1861386Species Yersinia pestis [TaxId:632] [238361] (1 PDB entry)
    5. 1861393Species Yersinia pseudotuberculosis [TaxId:633] [229814] (2 PDB entries)
  7. 1861402automated matches [190142] (18 species)
    not a true protein
    1. 1861403Species Aeropyrum pernix [TaxId:272557] [188092] (1 PDB entry)
    2. 1861405Species Bacillus subtilis [TaxId:1423] [193503] (14 PDB entries)
    3. 1861430Species Cow (Bos taurus) [TaxId:9913] [187265] (1 PDB entry)
    4. 1861432Species Escherichia coli [TaxId:562] [186867] (5 PDB entries)
    5. 1861452Species Human (Homo sapiens) [TaxId:9606] [256021] (5 PDB entries)
    6. 1861477Species Klebsiella pneumoniae [TaxId:272620] [193517] (1 PDB entry)
    7. 1861480Species Malaria parasite (Plasmodium knowlesi) [TaxId:5850] [225033] (1 PDB entry)
    8. 1861482Species Mycobacterium tuberculosis [TaxId:1773] [189596] (2 PDB entries)
    9. 1861487Species Plasmodium falciparum [TaxId:36329] [186993] (3 PDB entries)
    10. 1861497Species Plasmodium vivax [TaxId:5855] [188970] (1 PDB entry)
    11. 1861499Species Salmonella enterica [TaxId:904139] [196952] (5 PDB entries)
    12. 1861510Species Salmonella typhimurium [TaxId:99287] [187772] (1 PDB entry)
    13. 1861514Species Sulfolobus solfataricus [TaxId:2287] [187383] (2 PDB entries)
    14. 1861533Species Trichomonas vaginalis [TaxId:5722] [187838] (9 PDB entries)
    15. 1861550Species Vibrio cholerae [TaxId:243277] [189490] (2 PDB entries)
    16. 1861565Species Vibrio cholerae [TaxId:666] [188799] (2 PDB entries)
    17. 1861580Species Yersinia pseudotuberculosis [TaxId:273123] [268417] (1 PDB entry)
    18. 1861583Species Yersinia pseudotuberculosis [TaxId:502800] [189524] (1 PDB entry)

More info for Family c.56.2.1: Purine and uridine phosphorylases

Timeline for Family c.56.2.1: Purine and uridine phosphorylases: